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国家重点基础研究发展计划: 作品数：273390被引量：1705681H指数：254; 导出分析报告; 相关作者：岑可法付小兵姚咏明徐滨士杨义先更多>>; 相关机构：中国科学院清华大学北京大学浙江大学更多>>; 相关期刊：更多>>; 相关主题：数值模拟英文力学性能气候变化影响因素更多>>; 相关领域：天文地球医药卫生理学农业科学更多>>

Inhibitory effect of procyanidin B2 and tannin acid on cholesterol esterase and their synergistic effect with orlistat被引量：2: 《Food Science and Human Wellness》2024年第1期360-369,共10页Xiangxin Li Yijing Pu Haitao Jiang Wenxiao Jiao Wenjun Peng Wenli Tian Weibo Jiang Xiaoming Fang; supported by the National Basic Research Program of China(‘973’program,2013CB127106)。; This study was aimed to analyze the effect of procyanidin B2(PC)and tannin acid(TA)on the activities of cholesterol esterase(CEase)and the inhibitory mechanisms of enzymatic activity.The interaction mechanisms were in...; 关键词：Cholesterol esterase POLYPHENOLS Interaction mechanisms Molecular dynamic simulation Synergistic effect

Activation of endogenous neurogenesis and angiogenesis by basic fibroblast growth factor-chitosan gel in an adult rat model of ischemic stroke被引量：6: 《Neural Regeneration Research》2024年第2期409-415,共7页Hongmei Duan Shulun Li Peng Hao Fei Hao Wen Zhao Yudan Gao Hui Qiao Yiming Gu Yang Lv Xinjie Bao Kin Chiu Kwok-Fai So Zhaoyang Yang Xiaoguang Li; supported by the National Natural Science Foundation of China,Nos.81941011(to XL),31771053(to HD),31730030(to XL),31971279(to ZY),31900749(to PH),31650001(to XL),31320103903(to XL),31670988(to ZY);the Natural Science Foundation of Beijing,Nos.7222004(to HD);a grant from Ministry of Science and Technology of China,Nos.2017YFC1104002(to ZY),2017YFC1104001(to XL);a grant from Beihang University,No.JKF-YG-22-B001(to FH)。; Attempts have been made to use cell transplantation and biomaterials to promote cell proliferation,differentiation,migration,and survival,as well as angiogenesis,in the context of brain injury.However,whether bioactiv...; 关键词：adult endogenous neurogenesis ANGIOGENESIS basic fibroblast growth factor-chitosan gel CHITOSAN functional recovery ischemic stroke neural stem cell newborn neuron

牵牛子化学拆分组分影响上焦水饮内停模型大鼠药效学研究: 《中药药理与临床》2023年第6期70-75,共6页徐静孙延平高宁王宇梁华王秋红匡海学; 国家重点基础研究发展计划(973计划)项目(编号:2013CB531801);国家自然科学基金资助项目(编号:81473563);国家自然科学基金青年科学基金项目(编号:81503271);黑龙江省自然科学基金项目(编号:JJ2022LH1048);黑龙江省中医药经典普及化研究专项课题(编号:ZYW2023-003、ZYW2022-066);黑龙江省博士后科研启动金资助项目(编号:LBH-Q21045)。; 目的:探讨牵牛子水煎液及化学拆分组分对大鼠上焦水饮内停模型药效学研究,寻找牵牛子对上焦水饮内停模型作用的药效物质基础。方法:采用复合造模因素(大鼠腹部皮下注射异丙肾上腺素+气管插管+寒冷刺激)建立上焦水饮内停模型。模型建立...; 关键词：牵牛子树脂苷多糖上焦水饮内停模型异丙肾上腺素

Petrogenesis of granitic pegmatite veins:Perspectives from major element and B isotope in tourmalines,Chakabeishan,Northern Tibetan Plateau: 《Geoscience Frontiers》2023年第5期267-279,共13页Wenli Sun Zhidan Zhao Yaoling Niu Chunjing Wei Guochen Dong Xiaowei Li Wanming Yuan Tao Wang Bingzhang Wang Tong Pan Jie Han Hongliang Cao Yan Tang Dicheng Zhu; supported by the National Natural Science Foundation of China(Grant Nos.92062217,42121002,42073035);Second Tibetan Plateau Scientific Expedition and Research(STEP)program(Grant No.2019QZKK0702);111 Project of the Ministry of Science and Technology of China(Grant No.B18048);the University Innovation Foundation of Gansu Education Department(Grant No.2021A-230).; The petrogenesis of regionally zoned granitic pegmatite veins remains debated.Because of the economic significance,we carried out a study on the Chakabeishan(CKBS)pegmatite-type Li-Be deposit,eastern North Qaidam Tect...; 关键词：PETROGENESIS PEGMATITE TOURMALINE Boron isotope Major element

液体火箭发动机结构动力学设计关键技术综述被引量：7: 《航空学报》2023年第10期32-48,共17页杜大华李斌; 国家重点基础研究发展计划(613321);装备预研共用技术项目(41410040202)。; 随着液体火箭发动机技术的发展,结构动力学问题成为影响发动机寿命及可靠性的关键技术之一。经过多年努力,发动机结构从最初的静强度、安全寿命设计思想逐步发展为以动静强度联合、经济寿命设计为指导的研制理念和方法,并在型号中得到...; 关键词：动力学动强度疲劳寿命液体火箭发动机

商陆不同组分对上焦水饮内停大鼠模型药效学研究: 《中药药理与临床》2023年第5期96-100,共5页徐静李晓亮高宁梁华王秋红匡海学; 国家重点基础研究发展计划(973计划)项目(编号:2013CB531801);国家重点研发计划项目(编号:2019YFC1708801);广东省重点领域研发计划(编号:2020B1111120002);国家自然科学基金资助项目(编号:81473563);国家自然科学基金青年科学基金项目(编号:81503271);国家自然科学基金资助项目(编号:82160702);黑龙江省自然科学基金项目(编号:JJ2022LH1048);海南省自然科学基(编号:Hnky2019ZD-24)。; 目的:探讨商陆水煎液及不同组分对大鼠上焦水饮内停模型药效学研究,寻找商陆对上焦水饮内停模型作用的药效物质基础。方法:采用复合造模因素(大鼠腹部皮下注射异丙肾上腺素+气管插管+寒冷刺激)建立上焦水饮内停模型,模型建立后开始给予...; 关键词：商陆多糖上焦水饮内停模型异丙肾上腺素

Pan-genome and transcriptome analyses provide insights into genomic variation and differential gene expression profiles related to disease resistance and fatty acid biosynthesis in eastern black walnut (Juglans nigra)被引量：3: 《Horticulture Research》2023年第3期250-265,共16页Huijuan Zhou Feng Yan Fan Hao Hang Ye Ming Yue Keith Woeste Peng Zhao Shuoxin Zhang; supported by the National Natural Science Foundation of China(32070372,41471038,and 31800372);the Operating Services of Qinling National Forest Ecosystem Research Station financed by Ministry of Science and Technology of China,Natural Science Basis Research Plan in Shaanxi Province of China(2019JQ-641);Shaanxi Academy of Science Research Funding Project(2019 K-06);Science Foundation for Distinguished Young Scholars of Shaanxi Province(2023-JC-JQ-22).; Walnut(Juglans)species are used as nut crops worldwide.Eastern black walnut(EBW,Juglans nigra),a diploid,horticultural important woody species is native to much of eastern North America.Although it is highly valued fo...; 关键词：CROPS BREEDING black

Polyimides as Promising Materials for Lithium-Ion Batteries:A Review被引量：7: 《Nano-Micro Letters》2023年第9期74-102,共29页Mengyun Zhang Li Wang Hong Xu Youzhi Song Xiangming He; the financial support provided by the National Natural Science Foundation of China (nos. U21A20170 [X. He], 22279070 [L. Wang], and 52206263 [Y. Song]);the Ministry of Science and Technology of China (no. 2019YFA0705703 [L. Wang]);the “Explorer 100” cluster system of Tsinghua National Laboratory for Information Science and Technology for their facility support; Lithium-ion batteries(LIBs)have helped revolutionize the modern world and are now advancing the alternative energy field.Several technical challenges are associated with LIBs,such as increasing their energy density,im...; 关键词：Polyimides SEPARATORS Binders Solid-state electrolytes LITHIUM-ION

Implantable and biodegradable closed‐loop devices for autonomous electrotherapy: 《SmartMat》2023年第3期5-8,共4页Xiaoying Zhang Darakhshan Mehvish Hui Yang; Ministry of Science and Technology of China,Grant/Award Number:2018YFA0703200;National Natural Science Foundation of China,Grant/Award Number:51973154;National Innovation Group“Organic Integrated Circuit Core Material Foundation”,Grant/Award Number:52121002;Natural Science Foundation of Tianjin,Grant/Award Number:20JCZDJC00680;Haihe Laboratory of Sustainable Chemical Transformations。; Implantable electronic devices as a valuable biomedical tool are used to treat chronic diseases.However,traditional pacemakers exist a serious risk of complications.A biodegradable,closed‐loop sensor‐actuator system...; 关键词：autonomous electrotherapy biodegradable devices implantable devices

Jahn-Teller Effect Directed Bandgap Tuning of Birnessite for Pseudocapacitive Application: 《Energy & Environmental Materials》2023年第3期222-228,共7页Sheng Zhu Yuechao Wang Jinshu Zhang Jian Sheng Feng Yang Meng Wang Jiangfeng Ni Hong Jiang Yan Li; supported by Ministry of Science and Technology of China(2016YFA0201904);National Natural Science Foundation of China(21631002,52172219,51872192);Projects of International Cooperation and Exchanges NSFC(22120102004);Beijing National Laboratory for Molecular Sciences(BNLMS-CXTD-202001);the Jiangsu Natural Science Foundation(No.BK20180002);Fundamental Research Program of Shanxi Province(202103021223019).; Birnessite M_(x)MnO_(2)(M=Na^(+),K^(+),etc.)has emerged as a promising alternative to the classical MnO_(2)material owing to its improved pseudocapacitive performance for energy storage.Understanding their structure–...; 关键词：BIRNESSITE charge storage Jahn–Teller effect manganese dioxide SUPERCAPACITOR

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