This work was supported by the National Natural Science Foundation of China(21304099,51203162,51103159,51373177);the National High Technology Research and Development Program(2014AA020708,2012AA022703,2012AA020804);the Instrument Developing Project of the Chinese Academy of Sciences(YZ201253,YZ201313);the Open Funding Project of the National Key Laboratory of Biochemical Engineering(Y22504A169);the‘Strategic Priority Research Program’of the Chinese Academy of Sciences(XDA09030301-3);Beijing Natural Science Foundation(Z141100000214010).
Long-circulating drug carriers are highly desirable in drug delivery system.However,nonspecific protein adsorption leaves a great challenge in drug delivery of intravenous administration and significantly affects both...