This work was supported by National Natural Science Foundation of China (No 30271558); Key projects of National Science and Technology Pillar Program (2012ZX09301001-006 and 2012zx09302003) and the Public Service Platform Project of Shanghai Science and Technology Committee (11DZ2292500).
Aim: Tetrandrine, an alkaloid with a remarkable pharmacological profile, induces oxidative stress and mitochondrial dysfunction in hepatocytes; however, mitochondria are not the direct target of tetrandrine, which pr...
project supported by the National Natural Science Foundation of China (№ 30271558).
Aim: Correlation of cytochrome P450 (CYPs) with preneoplastic changes in the early stage of hepatocarcinogenesis is still unclear. To detect the expression of carcinogen-metabolizing related microsomal P450 enzymes, n...