supported by the grants from the National Key Basic Research Program of China(2007CB512406);the National Natural Science Foundation of China(30571732);National"863"Fund Grant of China(2006AA02A254).
The complement C5 anaphylatoxin receptor is a member of the seven transmembrane-spanning G protein-coupled receptor superfamily that signals through Gcxi and Gtz16. C5aR is mostly expressed on neutrophils, macrophages...