Project supported by the National Basic Research Program of China(No G 1999054000);the National Natural Science Foundation of China(No 30170302);the Basic Research Program of Shanghai(№ 02JC14011).
Aim: Botulinum neurotoxins (BoNT) abort the process of neurotransmitter release at presynaptic motor nerve terminals, causing muscle paralysis, The ability of botulinum toxin to produce its effect is dependent on t...