supported by the National Natural Science Foundation of China (90713033, 30901307, and 30772497);the National Basic Research Program of China (2007CB815800)
Toll-like receptors (TLRs) and NK cell receptors are the most important receptor superfamilies in innate immunity. TLRs act as the sensor of external pathogens, while NK cells detect alterations in endogenous protein ...
This work was supported by grants from the National Basic Research Program (2007CB815800 and 2011CB946101), the State High-Tech Development Project (2008AA092603), International S&T Cooperation Program from the Ministry of Science and Technology of China (2007DFA30840), the Ministry of Education (0107), and the National Natural Science Foundation of China (30901305, 30730089), and the Fundamental Research Funds for the Central Universities (1 l lgzdl6). Anlong Xu is recipient of "Outstanding Young Scientist Award" from the National Natural Science Foundation of China.
The MyD88-independent pathway, one of the two crucial TLR signaling routes, is thought to be a vertebrate innovation. However, a novel Toll/interleukin-1 receptor (TIR) adaptor, designated bbtTICAM, which was identi...
supported by the National Basic Research Program of China(Grant No. 2007CB815800);the National High Technology Research and Development Program of China(Grant No. 2006330004104456);the National Natural Science Foundation of China(Grant Nos. 30300264,30270693 and 30570967)
Smad family proteins are identified as intracellular signal mediators of the TGF-β superfamily.In this study,we identified two novel members of the Smad family,termed as AmphiSmad1/5/8 and AmphiSmad4,from Chinese amp...
Supported by the National Natural Science Foundation of China (Grant Nos. 30270693 and 30570967);the Ministry of Science and Technology of China (Grant No. 2007CB815800)
Myocyte enhancer factor 2 proteins are members of MADS family of transcription factors, which can control the expression of muscle-specific genes in vertebrates. However, not all Mef2 genes are es-sential for muscle d...