国家重点基础研究发展计划(2011CB504403)

作品数：4被引量：11H指数：2
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ROCK Inhibition with Fasudil Promotes Early Functional Recovery of Spinal Cord Injury in Rats by Enhancing Microglia Phagocytosis被引量：8
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2016年第1期31-36,共6页付佩彩 唐荣华 万跃 谢敏杰 王伟 骆翔 喻志源 
supported by grants from Natural Science Foundation of China(No.81471200 and No.81000521);National Basic Research Program of China(No.2011CB504403);the Young Medical Scientists Project of Wuhan(No.2013-12)
Emerging evidence indicates that microglia activation plays an important role in spinal cord injury（SCI） caused by trauma. Studies have found that inhibiting the Rho/Rho-associated protein kinase（ROCK） signaling p...
关键词：Rho/ROCK microglia spinal cord injury phagocytosis 
Cellular Expression Profile of RhoA in Rats with Spinal Cord Injury
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第5期657-662,共6页魏文洁 喻志源 杨怀洁 谢敏杰 王伟 骆翔 
supported by grants from National Natural Science Foundation of China(Nos.81000521 and 81471200);National Basic Research Program of China(No.2011CB504403)
RhoA, a small GTPase, is involved in a wide array of cellular functions in the central nerv- ous system, such as cell motility, cytoskeleton rearrangement, transcriptional regulation, phagocytosis and cell growth. It ...
关键词：RHOA spinal cord injury nerve cells 
Different Responses of Cell Cycle between Rat Vascular Smooth Muscle Cells and Vascular Endothelial Cells to Paclitaxel被引量：3
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2014年第3期370-375,共6页静亮 彭希 谢敏杰 喻志源 王伟 
supported by grants from National Natural Science Foundation of China(No.81030021);National Basic Research Program of China(No.2011CB504403)
Summary： Although previous reports showed dmg-eluting stent （DES） could effectively inhibit neointima formation, in-stent restenosis （ISR） remains an important obstacle. The purpose of this study was to investiga...
关键词：vascular smooth muscle cells vascular endothelial cells PACLITAXEL drug-eluting stent 
Small RNA Interference-mediated Gene Silencing of TREK-1 Potassium Channel in Cultured Astrocytes
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2012年第6期849-855,共7页吴潇 唐荣华 刘阳 宋景娇 喻志源 王伟 谢敏杰 
supported by grants from the National Natural Science Foundation of China (No.30971007);the Natural Science Foundation of Hubei Province for Outstanding Young Scholars (No.2010CDA103);the National Basic Research Program(No.2011CB504403)
This study was aimed to examine the effect of TREK-1 silencing on the function of astrocytes. Three 21-nucleotide small interfering RNA (siRNA) duplexes (siT1, siT2, siT3) targeting TREK-1 were constructed. Cy3-labele...
关键词：TREK-1 ASTROCYTES small interfering RNA ISCHEMIA 
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