国家重点基础研究发展计划(2012CB910204)

作品数：3被引量：3H指数：1
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相关作者：胡颖嵩冯峰刘迎芳更多>>
相关机构：中国科学院大学中国科学院更多>>
相关期刊：《Cellular & Molecular Immunology》《生物化学与生物物理进展》《Acta Biochimica et Biophysica Sinica》更多>>
相关主题：NDK鲍曼不动杆菌核苷二磷酸激酶晶体结构英文更多>>
相关领域：生物学轻工技术与工程农业科学更多>>
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鲍曼不动杆菌核苷二磷酸激酶的结构和功能研究（英文）被引量：2
《生物化学与生物物理进展》2015年第3期260-267,共8页胡颖嵩 冯峰 刘迎芳 
supported by grants from National Basic Research Program of China(2011CB910304,2012CB910204)~~
近年来,鲍曼不动杆菌(Acinetobacter baumannii)在医院里越来越受到人们的关注,尤其是在重症监护病房(ICUs).它以强大的多重耐药性(multiresistance)而闻名.核苷二磷酸激酶(nucleoside diphosphate kinase,NDK)是一种进化上非常保守的酶...
关键词：鲍曼不动杆菌 核苷二磷酸激酶(NDK) 晶体结构 
Structural dissection of Hippo signaling
《Acta Biochimica et Biophysica Sinica》2015年第1期29-38,共10页Zhubing Shi Shi Jiao Zhaocai Zhou 
This work was supported by the grants from the 973 program of the Ministry of Science and Technology of China （No. 2012CB910204）, the National Natural Science Foundation of China （Nos. 31270808, 31300734, 31470736, and 31470868）, the Science and Technology Commission of Shanghai Municipality （Nos. 11JC14140000 and 13ZR1446400）, and the ＇Cross and Cooperation in Science and Tech- nology Innovation Team＇ Project of the Chinese Academy of Sciences.
The Hippo pathway controls cell number and organ size by restricting cell proliferation and promot- ing apoptosis, and thus is a key regulator in development and homeostasis. Dysfunction of the Hippo pathway correlate...
关键词：Hippo pathway three-dimensional structure protein-protein/DNA interaction regulatory mechanism 
Germinal center kinases in immune regulation被引量：1
《Cellular & Molecular Immunology》2012年第6期439-445,共7页Hailei Yin Zhubing Shi ShiJiao Cuicui Chen Wenjia Wang Mark I Greene Zhaocai Zhou 
This work was supported by the 973 Program of the Ministry of Science and Technology of China （2010CB529700 and 2012CB910204）, the National Natural Science Foundation of China （NSFC10979005 and NSFC30970566） and the Science and Technology Commission of Shanghai Municipality （11JC14140000）. Dr ZZ is a scholar of the Hundred Talents Program of the Chinese Academy of Sciences. Dr Greene is supported by grants from the NIH, NCI, the Abramson Family Research Institute and the BCRF.
Germinal center kinases （GCKs） participate in a variety of signaling pathways needed to regulate cellular functions including apoptosis, cell proliferation, polarity and migration. Recent studies have shown that GCK...
关键词：germinal center kinases immune regulation signal transduction 
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