supported by the National Natural Science Foundation of China (30870827)
A substitution on an amino acid sequence can be defined as "intolerant" (non-neutral) or "tolerant" (neutral) according to whether or not it detectably alters protein phenotypes (e.g.,
supported by the National Natural Science Foundation of China(30870827)
Zinc ion is key physiological importance in mammalian tissues. It is a major structural component of many proteins and acts as co-factors for the activity of many enzymes that
supported by the National Natural Science Foundation of China (30870827)
The methods measuring the ‘‘coupling behavior’’ have potentially important applications with respect to evaluating the long range cross-correlation between two physiological systems.