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国家自然科学基金(31021062): 作品数：13被引量：38H指数：3; 导出分析报告; 相关作者：孙飞陆久维翟宇佳陈邵宏庞效云更多>>; 相关机构：中国科学院南京大学更多>>; 相关期刊：《生命科学》《生物物理学报》《Molecular Plant》《Cell Research》更多>>; 相关主题：CRYSTAL_STRUCTURESTRUCTUREREVEALSHUMANMCU更多>>; 相关领域：生物学理学医药卫生电气工程更多>>

Crystal Structure Analysis of Extrinsic PsbP Protein of Photosystem II Reveals a Manganese- Induced Conformational Change: 《Molecular Plant》2015年第4期664-666,共3页Peng Cao Yuan Xie Mei Li Xiaowei Pan Hongmei Zhang Xuelin Zhao Xiaodong Su Tao Cheng Wenrui Chang; This research was financially supported by grants from the National Natural Science Foundation of China （Grant No. 31100534, 31021062 and 31170703）, the Ministry of Science and Technology （973 Programs, Grant No. 2011CBA00902）, and the Strategic Priority Research program of the Chinese Academy of Sciences （XDB08020302）.ACKNOWLEDGMENTS We thank Alberta Pinnola for technical assistance on the maize cultivation and PSII-BBY extraction, We thank Zhenfeng Liu, Minrui Fan, and Jiping Zhang for helpful discussion. We are grateful to Yi Han and Shengquan Liu at the Institute of Biophysics, CAS. the staff of beamline BL17U at the Shanghai Synchrotron Radiation Facility. and the staff of beamlines BL1A, BL17A, and NW12A at the Photon Factory, KEK （Tsukuba, Japan） for technical support, No conflict of interest declared.; The Mn cluster （Mn4CaO5） on the thylakoid luminal side of photosystem II （PSII） catalyzes the photosynthetic oxygen-evolving reaction, an essential process for life on Earth. In higher plants and green algae, the ...

Structural implications of Dpy30 oligomerization for MLL/SET1 COMPASS H3K4 trimethylation被引量：1: 《Protein & Cell》2015年第2期147-151,共5页Hongmei Zhang Mei Li Yu Gao Chenjun Jia Xiaowei Pan Peng Cao Xuelin zhao Jiping Zhang Wenrui Chang; We thank the staff of beamline 17U at the Shanghai Synchrotron Radiation Facility for technical support during data collection and Y. Y. Chen for help with the ITC assay. This work was supported by the National Natural Science Foundation of China （Grant Nos. 30900230 and 31021062） and the National Basic Research Pro- gram （973 Program）（No. 2011CBA00902）. Hongmei Zhang, Mei Li, Yu Gao, Chenjun Jia, Xiaowei Pan, Peng Cao, Xuelin Zhao, Jiping Zhang, and Wenrui Chang declare that they have no conflict of interest. This article does not contain any studies with human or animal subjects performed by the any of the authors.; Dear Editor, The methylation modifications of histone 3 lysine 4 （H3K4） have essential effects on biological processes including gene expression and transcription, cell cycle progression, and DNA repair. From yeast ...

Structural biology study of human TNF receptor associated factor 4 TRAF domain被引量：2: 《Protein & Cell》2013年第9期687-694,共8页Fengfeng Niu Heng Ru Wei Ding Songying Ouyang Zhi-Jie Liu; the Ministry of Health of China(grant 2013ZX10004-602);the National Basic Research Program(973 Program)(Nos.2013CB911103,2009DFB30310,2009CB918803 and 2011CB911103);the National Natural Science Foundation of China(Grant Nos.31270795,31200559,31070660 and 31021062).; TRAF4 is a unique member of TRAF family,which is es-sential for innate immune response,nervous system and other systems.In addition to being an adaptor protein,TRAF4 was identifi ed as a regulator protein in recent st...; 关键词：TRAF4 TRAF domain crystal structure ad-ditional loop phosphorylation site

Structure of the catalytic domain of a state transition kinase homolog from Micromonas algae: 《Protein & Cell》2013年第8期607-619,共13页Jiangtao Guo Xuepeng Wei Mei Li Xiaowei Pan Wenrui Chang Zhenfeng Liu; We thank the staffs at Shanghai Synchrotron Radiation Facility(SSRF)as well as Yi Han and Shengquan Liu at the X-ray core facility at the Institute of Biophysics(IBP),Chinese Academy of Sciences(CAS)for their technical support during crystal screening and data collection.We also thank Hongmei Zhang for the as sistance with molecular biology and biochemistry,Zhensheng Xie and Fuquan Yang at the Proteomic Core Facility Center of IBP,CAS and Jieyuan Liu at the Center of Biomedical Analysis of Tsinghua University for their technical assistance at the Mass Spectrometry analysis.This work was supported by the National Basic Research Program(973 Program)(Nos.2011CBA00902 and 2011CBA00903)awarded to W.R.C.and Z.F.L.,respectively;the National Natural Science Foundation(Grant No.31021062).; Under natural environments,plants and algae have evolved various photosynthetic acclimation mechanisms in response to the constantly changing light conditions.The state transition and long-term response processes in p...; 关键词：Stt7/STN7 kinase state transition PHOSPHORYLATION

线粒体钙离子转运的研究进展被引量：16: 《生物物理学报》2013年第3期167-180,共14页陆久维翟宇佳孙飞; 国家"973"计划项目(2011CB910301);国家自然科学基金创新群体项目(31021062)~~; 线粒体内的钙离子浓度对于线粒体的ATP合成、线粒体通透性转变孔道的开放及细胞质内钙信号的调节具有重要影响。线粒体的钙离子转运调节平衡是线粒体除合成ATP和诱导细胞凋亡以外的又一重要功能。线粒体中存在钙吸收和钙释放两种重要的...; 关键词：线粒体钙离子吸收钙离子释放 MCU NCLX

Dynactin辅助dynein进行细胞内物质运输的研究进展被引量：1: 《生物物理学报》2012年第10期785-793,共9页王圣柳孙飞; "973"计划项目(2011CB910301);国家自然科学基金创新群体项目(31021062)~~; 胞质动力蛋白(cytoplasmic dynein)是沿微管向负极运动的马达蛋白,参与细胞内多种物质的运输,运输的货物(cargo)小至信使RNA和蛋白质,大至细胞器和囊泡。动力蛋白只有与动力激活蛋白(dynactin)结合在一起时才有活性。动力激活蛋白是一...; 关键词：动力蛋白动力激活蛋白微管负向运动持续性行走

Structural insights into the assembly of human translesion polymerase complexes被引量：1: 《Protein & Cell》2012年第11期864-874,共11页Wei Xie Xuan Yang Min Xu Tao Jiang; supported financially by the National Basic Research Program(973 Program)(No.2011CB910302);the National Natural Science Foundation of China(Grant Nos.31025009,31021062 and 31200558).; In addition to DNA repair pathways,cells utilize translesion DNA synthesis(TLS)to bypass DNA lesions during replication.During TLS,Y-family DNA polymerase(Polη,Polκ,Polιand Rev1)inserts specific nucleotide opposite...; 关键词：translesion DNA synthesis Rev1 Polκ Polζ complex structure

Crystal structure of ISG54 reveals a novel RNA binding structure and potential functional mechanisms被引量：8: 《Cell Research》2012年第9期1328-1338,共11页Zhenlin Yang Huanhuan Liang Qian Zhou Ying Li Haiwei Chen Wen Ye Danying Chen Joy Fleming Hongbing Shu Yingfang Liu; We thank our colleagues Drs Hongfei Wang and Lijie Wu for crystal data collection. We thank Yuanyuan Chert and Xiaoxia Yu in core facility center （Institute of Biophysics, CAS） for technical assistance with the ITC, SPR and ultra-centrifugation experiments. We thank colleagues at the Photon factory, KEK （Japan） and SSRF （China） for assistance in the use of the synchrotron resource. We also thank Drs Xiufan Liu and Shunlin Hu （Yangzhou University） for providing the cDNA of ZJ1-NDV. This work was supported by grants to YL from the Ministry of Science and Technology （863 Project 2006AAO2A314; 973 Programs 2007CB914303, 2011CB910304 and 2012CB9 10204） and the National Natural Science Foundation of China （30925011, 31030024 and 31021062）.; Interferon-stimulated gene 56 （ISG56） family members play important roles in blocking viral replication and regulating cellular functions, however, their underlying molecular mechanisms are largely unclear. Here, we...; 关键词：structure biology ISG54

Crystal structure of the ubiquitin-like domain of human TBK1被引量：6: 《Protein & Cell》2012年第5期383-391,共9页Jian Li Jun Li Andrea Miyahira Jian Sun Yingfang Liu Genhong Cheng Huanhuan Liang; supported by grants from the State Key Development Program for Basic Research of the Ministry of Science and Technology of China(973 Program)(Grant Nos.2011CB910304 and 2012CB910204)to YL;the National Natural Science Foundation of China(Grant Nos.30925011,31030024 and 31021062).; TANK-binding kinase 1(TBK1)is an important enzyme in the regulation of cellular antiviral effects.TBK1 regulates the activity of the interferon regulatory factors IRF3 and IRF7,thereby playing a key role in type I int...; 关键词：TBK1 ubiquitin-like domain crystal struc-ture hydrophobic patch

线粒体运动及其相关的细胞骨架和蛋白被引量：2: 《生物物理学报》2011年第12期1019-1029,共11页陈邵宏庞效云孙飞; "973"计划项目(2011CB910301);国家自然科学基金创新群体项目(31021062);中国科学院知识创新工程重要方向项目(KSCX2-EW-J-3); 线粒体是真核细胞中十分重要的细胞器,它密切影响着细胞能量的供应、钙离子浓度的稳态以及细胞凋亡等过程。因此,线粒体恰当的分布关乎细胞的功能和生存,这就涉及到线粒体的运动和固定。在极化细胞(如神经细胞和出芽的芽殖酵母)中,线粒...; 关键词：线粒体运动神经细胞芽殖酵母细胞骨架马达蛋白衔接蛋白

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