国家自然科学基金(s30571672)

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PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress被引量：4
《Science China(Life Sciences)》2008年第7期630-639,共10页AN Run1 ,2,DONG ChenFang 2,LEI YanJun 1,2,HAN Lu 2,LI Ping 2,CHEN JianMing 2,WANG GuiRong 2, SHI Qi 2 ,GAO Chen 2 ,JIANG HuiYing 2 ,ZHOU Wei 2 ,HAN Jun 2 ,CHU YongLie 1 ,DONG XiaoPing 2 1School of Medicine,Xi’an JiaoTong University,Xi’an 710061,China 2State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,YingXin Rd 100,Beijing 100052,China 
the National Science and Technology Task Force Project(Grant No.2006BAD06A13-2);National Basic Research Program(973 Program)of China(Grant No.2007CB310505);National Natural Science Foundation of China(Grant Nos.30571672,30500018 and 30771914)
One of the physiological functions of cellular prion protein(PrP C )is believed to work as a cellular resistance to oxidative stress,in which the octarepeats region within PrP plays an important role.However,the detai...
关键词：PRION protein oxidative stress GLUTATHIONE PEROXIDASE reactive oxygen species cell VIABILITY 
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