国家自然科学基金(30830111)

作品数:2被引量:10H指数:1
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相关期刊:《Acta Pharmacologica Sinica》更多>>
相关主题:INHIBITSGSK-3ΒGEMCITABINECYCLIN_D1ASPIRIN更多>>
相关领域:生物学医药卫生化学工程农业科学更多>>
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Aspirin inhibits proliferation of gemcitabine-resistant human pancreatic cancer cells and augments gemcitabine-induced cytotoxicity被引量:10
《Acta Pharmacologica Sinica》2010年第1期73-80,共8页Yan-qiu OU Wen bo ZHU Yan LI Peng-xin QIU Yi-jun HUANG Jun XIE Song-min HE Xiao-ke ZHENG Tian-dong LENG Dong XU Guang-mei YAN 
This work was supported by Key program, National Natural Science Foundation of China (No 30830111) and National Natural Science Foundation of China (No 330801408).
Aim: To investigate whether aspirin is able to augment gemcitabine-induced cytotoxicity in human pancreatic cancer cells. Methods: Two gemcitabine-insensitive human pancreatic cancer cell lines, PANC-1 and Capan-1, ...
关键词:ASPIRIN human pancreatic cancer GEMCITABINE apoptosis GSK-3Β cyclin D1 Bcl-2 
Orphan nuclear receptor Nur77 is required for the differentiation of C6 glioma cells induced by cholera toxin
《Acta Pharmacologica Sinica》2009年第11期1543-1549,共7页Dong XU Yi-jun HUANG Yan LI Wei YIN Guang-mei YAN 
Acknowledgements Project was supported by National Natural Science Foundation of China, Key program (No 30830111).
Aim: To investigate a possible regulator gene involved in the cholera toxin-induced differentiation of rat C6 glioma cells. Methods: The global changes in the mRNA expression pattern induced by cholera toxin were an...
关键词:cholera toxin malignant glioma DIFFERENTIATION orphan nuclear receptor nur77 
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