the National Natural Science Foundation of China(№ 30570807);the Natural Science Foundation of Zhejiang Province,China(№ Z303761)
Aim: To evaluate the effect of C-C chemokine receptor 3 (CCR3) blockade on pulmonary inflammation and mucus production in allergic mice. Methods: We used the synthetic peptide of the CCR3 NH2-terminal as the immun...
Project supported in part by the National Natural Science Foundation of China(No 30570807);key programs of the Natural Science Foundation of Zhejiang Province,China(№Z303761);key programs of Science and Technology Association of Zhejiang Province(№2003C24002).
Aim: To explore the effect of a rat anti-mouse CC-chemokine receptor-3 (CCR3) monoclonal antibody (CCR3 mAb) on airway eosinophilia and mucus overproduction in asthmatic mice. Methods: An asthma model was sensit...
This work was partially supported by the National Natural Science Foundation of China (No. 30570807).
Background Asthma is a chronic airway disease with inflammation characterized by physiological changes (airway hyper-responsiveness, AHR) and pathological changes (inflammatory cells infiltration and mucus product...