《Journal of Chinese Pharmaceutical Sciences》

作品数：2857被引量：3650H指数：16
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《Journal of Chinese Pharmaceutical Sciences》
主办单位：中国药学会
最新期次：2025年2期更多>>
发文主题：CHINESEPHARMACOKINETICSJOURNALDETERMINATIONHPLC更多>>
发文领域：医药卫生文化科学理学化学工程更多>>
发文作者：屠鹏飞张强崔景荣姜勇李润涛更多>>
发文机构：北京大学北京医科大学沈阳药科大学中国医学科学院北京协和医学院更多>>
发文基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家科技支撑计划更多>>
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Enhancing spleen function for effective hyperuricemia treatment
《Journal of Chinese Pharmaceutical Sciences》2025年第2期99-108,共10页Qian Deng Zining Peng Fanyu Meng Weitian Yan Nian Liu Jiangyun Peng 
National Natural Science Foundations of China(Grant No.81960863);the Education Department of Yunnan Province(Grant No.2023Y0463 and 2024Y380);Yunnan Clinical Research Center for rheumatism in Traditional Chinese Medicine(Grant No.202405AJ310004).
Hyperuricemia(HUA)is a metabolic disorder characterized by elevated levels of uric acid in the blood,resulting from either increased production or decreased excretion of uric acid.This condition has reached epidemic p...
关键词：Strengthening the spleen HYPERURICEMIA DIAGNOSIS TREATMENT 
Synthesis of a novel pharmaceutical excipient: An anion exchange resin
《Journal of Chinese Pharmaceutical Sciences》2025年第2期109-125,共17页Zhannuan Yin Xianghuan Meng Yingshu Feng Ke Li Xinyi Tang Hongfei Liu Haibing He Wei Mi 
2023 Nantong Jianghai Talents Project,the Nantong Social Livelihood Science and Technology Plan for 2023;the 2022 New Drugs and Platform Enhancement Project of the Yangtze Delta Drug Advanced Research Institute.Additionally,support was p rovided by the Zhenjiang Science and Technology Project(Grant No.SH2020048);the China Postdoctoral Science Foundation(Grant No.2020M681532);the Jiangsu Planned Projects for Postdoctoral Research Funds(Grant No.2020Z209);the Natural Science Research Projects of Universities in Jiangsu Province(Grant No.20KJD350001).
The aim of this study was to develop a novel pharmaceutical excipient:an anion exchange resin.Initially,polystyrenedivinylbenzene(PS-DVB)microspheres were synthesized via suspension polymerization.Subsequently,these m...
关键词：Suspension polymerization reaction POLYSTYRENE-DIVINYLBENZENE Quaternarization reaction Anion exchange resin Fluidized bed coating method Pharmacokinetic research 
Effect of inonotus obliquus polysaccharide on chronic nonbacterial prostatitis and its effect on Th17/Treg immune imbalance
《Journal of Chinese Pharmaceutical Sciences》2025年第2期126-134,共9页Xiaoru Zhao Lihua Han Miao Hao Lili Peng Hongxia Yuan Qingshan Li 
Shanxi Province Traditional Chinese Medicine Administration Research Project(Grant No.2022ZYYC094);Science and technology innovation project of universities in Shanxi Province(Grant No.2022L342);Shanxi Leader Team of Medical Science&Technology Innovations(Grant No.2020TD02);Discipline Construction Project of Chinese Medicine Chemistry(Grant No.2024XKJS-25).
The aim of this study is to observe the therapeutic effect of Inonotus Obliquus Polysaccharide(IOP)on chronic nonbacterial prostatitis(CNP)and its effect on the helper T cells(Th17)and regulatory T cells(Treg)immune i...
关键词：Inonotus obliquus polysaccharide Chronic nonbacterial prostatitis TH17 TREG Th17/Treg balance 
Metabolomics analysis of femoral tissue reveals the impact of Anemarrhenae Rhizoma on metabolic pathways in osteoporotic rats
《Journal of Chinese Pharmaceutical Sciences》2025年第2期135-149,共15页Yuxin Wen Qi Jiang Zhuang Huang Pengyu Chen Xing Hong Qiong Wang Tao Huang Lintao Han 
Foundation items:Wuhan Health Research Fund(Grant No.WZ21A06);National Natural Science Foundation of China(Grant No.81903815)。
This study aimed to assess the therapeutic potential of Anemarrhenae Rhizoma(AR)in osteoporotic rats and to elucidate the metabolic pathways involved in AR’s role in alleviating osteoporosis(OP).OP was induced in rat...
关键词：Anemarrhenae Rhizoma OSTEOPOROSIS RATS Metabolomics 
Ferroptosis-related gene biomarkers in psoriasis:diagnostic potential and insights for traditional chinese medicine treatments
《Journal of Chinese Pharmaceutical Sciences》2025年第2期150-162,共13页Xiaoyan Ma Di Wu 
Yunnan Provincial Excellent Clinical Talents Training Project(the First Batch)(Yunnan Financial Society(2024)No.103).
This research aimed to identify and validate ferroptosis-related signature genes associated with psoriasis through a comprehensive bioinformatics approach,while also predicting potential traditional Chinese medicines(...
关键词：PSORIASIS Ferroptosis Fer-DEGs Traditional Chinese medicine prediction 
Deciphering the mechanism of action of Chaihu-Astragalus compound in the management of alcoholic liver fibrosis:A network pharmacology and molecular docking approach
《Journal of Chinese Pharmaceutical Sciences》2025年第2期163-174,共12页Xiaodong Zhu Xueshi Di Jinhui Sun 
National Natural Science Foundation of China(Grant No.81573969).
The present study aimed to analyze the potential mechanism of action of Chaihu-Astragalus in treating alcoholic liver fibrosis using network pharmacology and molecular docking techniques.We initially screened the acti...
关键词：Alcoholic liver fibrosis Chaihu-Astragalus Network pharmacology Molecular docking 
An investigation into the current status of post-marketing signal detection for pharmaceutical products in China:An interview-based study
《Journal of Chinese Pharmaceutical Sciences》2025年第2期175-184,共10页Xuelin Sun Yatong Zhang Dongfang Qian Siyuan Tan Zixuan Zhang Pengfei Jin Xin Hu 
China National Key Research and Development Program(Grant No.2020YFC2009000 and 2020YFC2009001);National High Level Hospital Clinical Research Funding(Grant No.BJ-2023-200);the project funding from the Drug Evaluation Center of the National Medical Products Administration(Grant No.CDRW20214001).
The aim of this study was to provide insights into the current status and primary methodologies employed by marketing authorization holders(MAHs)for signal detection.These insights are intended to offer valuable refer...
关键词：PHARMACOVIGILANCE Signal Marketing authorization holder Adverse drug reactions 
徐正仁团队完成Cyclopiane家族二萜天然产物的化学-酶法合成
《Journal of Chinese Pharmaceutical Sciences》2025年第2期185-187,共3页无 
2024年11月27日,北京大学药学院天然药物及仿生药物全国重点实验室徐正仁团队在学术期刊Angew.Chem.Int.Ed.发表了题为“Chemoenzymatic Synthesis of the Cyclopiane Family of Diterpenoid Natural Products”(Cyclopiane家族二萜天...
关键词：天然产物 二萜 重点实验室 学术期刊 天然药物 of 
汪贻广/陈斌龙团队开发一种溶酶体-线粒体级联靶向纳米策略高效调控肿瘤焦亡
《Journal of Chinese Pharmaceutical Sciences》2025年第2期188-189,共2页无 
2024年12月5日,北京大学药学院天然药物及仿生药物全国重点实验室汪贻广教授团队在国际知名学术期刊Journal of the American Chemical Society上发表了题为“Lysosome-Mitochondria Cascade Targeting Nanoparticle Drives Robust Pyro...
关键词：团队开发 北京大学药学院 重点实验室 溶酶体 学术期刊 焦亡 天然药物 
北京大学李鲜婵团队开发了一种脑组织单囊泡电化学分析方法实现了神经囊泡单胺类神经递质的原位定量监测
《Journal of Chinese Pharmaceutical Sciences》2025年第2期190-192,共3页无 
2024年12月20日,北京大学药学院天然药物及仿生药物全国重点室李鲜婵团队在Journal of the American Chemical Society杂志刊登了题为“Single-Vesicle Electrochemistry in Fresh Brain Slices Enables In-situ Quantification of Vesi...
关键词：电化学分析方法 单胺类神经递质 团队开发 单胺类递质 囊泡 李鲜 
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