OBJECTIVE:To present our experience with the surgical management of giant pituitary adenomas in a series of 50 cases operated on by an endoscopic endonasal approach.METHODS:A retrospective data analysis of all patient...
Recent in vitro studies highlighted G protein-coupled receptor kinase(GRK)2 andβ-arrestins as important players in driving somatostatin receptor(SSTR)desensitization and trafficking.Our aim was to characterize GRK2 ...
Prolactinomas are solitary benign neoplasms and resistance to dopamine agonists occur in a small percentage of prolactinomas.Multiple pituitary adenomas are reported in less than 1%of pituitary adenomas and rarely res...