Introduction.Respiratory Syncytial Virus (RSV) remains a significant health threat for infants, being the main cause of hospital admissions due to lower respiratory tract infections (LRTI) within this vulnerable popul...
Open Access funding enabled and organized by Projekt DEAL.
Pediatric oncology has always been a dynamic and everevolving field dedicated to understanding and combating cancers in children and adolescents.While survival rates for many pediatric malignancies have improved signi...
support from the Natural Science Foundation of China(No.81470304);the Key Project of Zhejiang Provincial Science and Technology Department(No.2019C03032).
Solid tumors account for more than 60%of all the pediatric malignancies and contribute substantially to the disease burden in China[1].Currently,there are five primary treatment strategies:surgery,radiation therapy,co...
Open Access funding enabled and organized by Projekt DEAL;The research of KM on pediatric cancer predisposition is supported by Deutsche Krebshilfe(70115888);Deutsche Forschungsgemeinschaft(KU3764/3-1);intramurale Forschungsförderung,University of Augsburg,Germany.FMC’s research on rhabdoid tumor disposition is supported by Deutsche Krebshilfe 70113981.
Purpose Cancer predisposition syndromes are genetic disorders that significantly raise the risk of developing malignancies.Although the malignant manifestations of cancer predisposition syndromes are well-studied,reco...
supported by National Key R&D Program of China(2019YFA0801900).
Background Glucose transporter 1 defciency syndrome(Glut1DS)was initially reported by De Vivo and colleagues in 1991.This disease arises from mutations in the SLC2A1 and presents with a broad clinical spectrum.It is a...
supported by grants from the General Administration of Sport of China,the National Natural Science Foundation of China(grant number 82273654 to YS);Natural Science Foundation of Beijing(grant number 7222247 to YS);Beijing Office for Education Sciences Planning(grant number BBAA22027 to YS).
Background We performed an umbrella review to synthesize evidence on the effects of physical activity(PA)interventions on indicators of physical and psychological health among children and adolescents,including body m...
Background The survival of children and adolescents with complex chronic conditions(CCCs)and/or life-limiting or life-threatening conditions(LLCs)is increasing,while estimating their prevalence is complex and limited....
National Natural Science Foundation of China(823B2087);Shanghai Municipal Health Commission(GWVI-11.2-XD16);National Natural Science Foundation of China Joint Fund Project(U23A20170);Shanghai Municipal Health Commission(Child Neurological and Psychological Development Screening and Intervention Project),Shanghai Key Laboratory of Child Brain and Development(24dz2260100).
Background Developmental delay(DD)poses challenges to children's overall development,necessitating early detection and intervention.Existing screening tools in China focus mainly on children with developmental issues ...
supported by The National Nature Science Foundation of China(grant number:82270309).
Background Digital technologies play an important role in improving the quality of healthcare services,however,many healthcare workers and students do not recognize this and have low levels of digital competencies and...
The incidence of chronic immune-mediated diseases is increasing worldwide across all age groups,affecting more than 10%of the general population[1,2].Immune-mediated diseases are also more likely to be associated with...