Introduction: Tuberculosis (TB) remains a significant public health challenge, particularly in high-endemicity settings where latent TB infections (LTBI) contribute to ongoing transmission. Early identification and ma...
Background: Latent tuberculosis can progress to active TB. To diagnose LTBI the TST is used, which shows cross reactivity with NTM and BCG, giving way to overdiagnosis of LTBI. The sophisticated QFT is also used to di...
Background: Circulating antibodies against specific M. tuberculosis (M. tb) antigens offer promising diagnostic biomarkers and an appealing alternative due to their ease of application, cost-effectiveness, and relativ...
Pneumcystis jirovecii is a pathogen that causes Pneumocystis pneumonia (PCP), an infection in (HIV/ADS) and other immunocompromised patients. The rare reports of P. jirovecii pneumonia in sub-Saharan Africa are contro...
This case report presents a 63-year-old male patient with a history of TB 20 years prior, who developed chronic cor pulmonale, right heart failure, and eventually died. The report emphasizes the serious long-term effe...
Background: The aim of this study was to evaluate the usefulness of two interferon-gamma release assays (IGRAs) (QuantiFERON-TB Plus (QFT-plus) and T-SPOT.TB assay) for patients suspected of having tuberculosis (TB) i...
Objective: In the context of increasing cases despite vaccination campaigns, a survey was conducted in the Bangui population from January 17 to 26, 2022, to evaluate the strains of Severe Acute Respiratory Infection C...
Objective: The COVID-19 pandemic has highlighted the need to strengthen diagnosis and genomic surveillance capacities. In 2021, Central African managed five waves of COVID-19 by integrating genomic surveillance into t...
This research focuses on the effects of migration on the TB infection rate and its prevention in Saudi Arabia, which has a large number of expatriates from TB-affected countries. Despite, based on the current global s...
Background: Tuberculosis (TB) is one of the major killer diseases among infectious diseases. The success of TB control depends on the capability of the health care system to detect and accurately manage TB cases. Tube...