Osteosarcomas are malignant neoplasms derived from undifferentiated osteogenic mesenchymal cells. It causes severe and permanent damage to human tissue and has a high mortality rate. The condition has the capacity to ...
supported by the National Natural Science Foundation of China (general program) (grant Nos.52178361,42407214);the National Outstanding Youth Science Fund Project of the National Natural Science Foundation of China (grant No.51722801).
An explanation of the meso-mechanism of sand granular materials for the uniqueness of critical state is presented by means of the discrete element method(DEM)under flexible boundary loading conditions.A series triaxia...
supported by the Training Plan of discipline Leader of Shanghai Pudong new area Health Commission(PWRd2022-04);Clinical Characteristic Discipline Construction program of Shanghai Pudong New Area Health Commission(PwYts2021-17).
Pulmonary arteriovenous fistul a(PAVF)represents an abnormal direct connection between the pulmonary artery and vein,circumventing the alveolar capillary network.A right-to-left shunt in the lungs precluding proper ga...
National Natural Science Foundation of China 82273961(Ming-Wei Wang),82073904(Ming-Wei Wang)and 81872915(Ming-Wei Wang);STI2030-Major Project(China)2021ZD0203400(Qingtong Zhou);Hainan Provincial Major Science and Technology Project(China)ZDKJ2021028(Dehua Yang and Qingtong Zhou).
To the Editor:Glucagon-like peptide-1(GLP-1)receptor(GLP-1R)is a well-established drug target for type 2 diabetes and obesity.It is activated by the endogenous hormone GLP-1(7-36)NH_(2)[GLP-1(7-36)hereafter]to maintai...
Supported by the 2021 Key Topic of the Qinghai Provincial Health System-Guiding Plan Topic,No.2021-WJZDX-43.
BACKGROUND At present,immune checkpoint inhibitors(ICIs)remain the 1st-line therapy me-thod for patients suffering from high microsatellite instability/deficient misma-tch repair metastatic colorectal cancer(mCRC).How...
The revitalization of the historic centre of Slany(Czech Republic)dealt by architects-experts in a historic town focused on their theoretical principles and verified practice.The bridge U Brodu is the first project of...
funded by the National Key Research and Development Program of China(2021YFA1501103);the National Science Fund for Distinguished Young Scholars of China(22225110);the National Science Foundation of China(22075166,22271177);the Young Scholars Program of Shandong University.
As the promising catalysts for the water-gas shift(WGS)reaction,the activity of Au-CeO_(2) composites is susceptible to the aggregation size and electronic state of Au species.Previous reports were extensively focused...
BACKGROUND Resection of hepatic metastasis from neuroendocrine tumors(NETs)improves quality of life and prolongs 5-year survival.Ablation can be utilized with surgery to achieve complete resection.Although several stu...
supported by the National Natural Science Foundation of China(81373584)。
Objective:To explore the mechanism of the Peiyuan Jieyu formula in treating depression by assessing its impact on a lipopolysaccharide-induced(LPS-induced)depression mouse model.Methods:We created a mouse model of dep...
American National Science Foundation and Spanish Ministerio de Economia y Competitividad provided financial support(EEBB-I-14-08326 to RM-P and EF-1241848 to BS);RM-P enjoys a postdoctoral contract(CEECIND/04084/2017)by ICETA-Instituto de Ciencias,Tecnologias e Agroambiente da Universidade do Porto and Fundacao da Ciencia e Tecnologia.Authors declare no conflict of interest.
Male competition conforms to a cost-benefit model,because while aggression may increase reproductive prospects,it can also increase the risk of injury.We hypothesize that an additional cost in aggressive males would b...