Α-CRYSTALLIN

作品数:5被引量:7H指数:1
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相关领域:医药卫生生物学更多>>
相关作者:王晓芹吴楠刘强王一余涛更多>>
相关机构:第三军医大学第三军医大学西南医院复旦大学更多>>
相关期刊:《重庆医学》《Tsinghua Science and Technology》《Insect Science》《Advances in Biological Chemistry》更多>>
相关基金:国家自然科学基金军队“十一五”科技攻关课题国家重点基础研究发展计划更多>>
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视网膜α-crystallins在增生性视网膜疾病中的研究进展
《中国临床医学》2020年第5期866-870,共5页徐雅慧 袁源智 
国家自然科学基金(81970817,81873680).
α-crystallins是小分子热休克蛋白家族(small-molecule heat shock protein,sHSP)的重要成员,包括αA-crystallin和αB-crystallin,在各类组织细胞中具有细胞保护和分子伴侣功能。近年来,多项研究发现,视网膜组织α-crystallins可利用...
关键词:α-crystallins 糖尿病视网膜病 黄斑变性 玻璃体视网膜病变 血管生成 上皮间质化转变 
Structure and interactions in α-crystallin probed through thiol group reactivity
《Advances in Biological Chemistry》2013年第5期427-439,共13页Sudipa Saha Kali Pada Das 
a-Crystallin is the major structural protein of eye lens of vertebrates. In human lens, the ratio of aA-crystallin to aB-crystallin was found to be 3:1. aA-Crystallin contains two cysteine residues at positions 131 an...
关键词:THIOL REACTIVITY Α-CRYSTALLIN DTNB Kinetics Molecular CHAPERONE Folding UNFOLDING of Α-CRYSTALLIN 
Characterization of three transcripts encoding small heat shock proteins expressed in the codling moth, Cydia pomonella (Lepidoptera: Tortricidae)被引量:6
《Insect Science》2011年第5期473-483,共11页Stephen F. Garczynski Thomas R. Unruh Christelle Guedot Lisa G. Neven 
Codling moth is a major pest of apples and pears worldwide. Increasing knowledge of how this insect responds to environmental stress will improve field and postharvest control measures used against it. The small heat ...
关键词:α-crystallin domain heat shock response qPCR 
Heat Treatment of Small Heat Shock Proteins α-Crystallin and Hsp16.3: Structural Changes vs. Chaperone-like Activity
《Tsinghua Science and Technology》2001年第5期406-409,共4页毛启龙 柯丹霞 昌增益 
Supported by the National Natural Science Foundation of China ( No.3 970 0 0 2 5 ) and the National Science Foundation for Outstanding Young Scientists in China ( No.3 972 5 0 0 8)
Both α crystallin from bovine eye lens and Hsp16.3 from Mycobacterium tuberculosis are members of the small heat shock protein family. They were preincubated at 100 ℃ for 15 min and then cooled on ice immedi...
关键词:chaperone   activity heat treatment small heat shock protein 
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