SUBTYPING

作品数：52被引量：158H指数：7
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相关领域：医药卫生更多>>
相关作者：钟琦刘维薇更多>>
相关机构：上海市第十人民医院更多>>
相关期刊：《Cellular & Molecular Immunology》《Quantitative Biology》《Reproductive and Developmental Medicine》《Virologica Sinica》更多>>
相关基金：国家自然科学基金上海市浦江人才计划项目霍英东教育基金上海市自然科学基金更多>>
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A novel metabolite-interacting protein(MIP)-based molecular subtyping construction and validation of IGFBP3 as a MiP-related oncogene in colorectal cancer
《Genes & Diseases》2025年第2期7-10,共4页Simeng Bao Yongmin Li Yu Liang Jianxun Dai Huolin Huang Bin Ma 
supported by grants from the Cultivation Program of National Science Foundation of Liaoning Cancer Hospital (China) (No.2021-ZLLH-03);Beijing Xisike Clinical Oncology Research Foundation (China) (No.Y-QL202101-0039);Medical and Industrial Cross Joint Fund of Dalian University of Technology-Liaoning Cancer Hospital (China) (No.LD2023027);The National Natural Science Foundation of China (No.82303131);the Liaoning Province Science and Technology Plan Joint Program (Applied Basic Research Project) (China) (No.2023JH2/101700150).
For prognosis and therapeutic response,colorectal cancer(CRC)patients are highly variable across stages,correlated to high inter-tumor heterogeneity at the molecular level.1 Therefore,molecular subtyping needs to be d...
关键词：colorectal cancer IGFBP3 
Heterogeneity of anoikis in triple-negative breast cancer subtyping and therapeutic implications
《Genes & Diseases》2025年第1期114-117,共4页Kun Fang Suxiao Jiang Zhengjie Xu Meng Luo Changsheng Yan 
supported by a Ningxia Reproductive Disease Clinical Medical Research Center Project(2023-LCYX003);Ningxia Hui Autonomous Region Natural Science Foundation Project(2022AAC03748);Ningxia Hui Autonomous Region Natural Science Foundation Project(2021AAC03523);Yinchuan Science and Technology Innovation Project(2023SF25);Basic research project of Yinchuan Maternal and Child Health Hospital(2022NYFYCX05);Basic research project of Yinchuan Maternal and Child Health Hospital(2023NYFYCX01).
Triple-negative breast cancer(TNBC)is an inherently heterogeneous malignancy at the biological and clinical levels,occupying around 15%of diagnosed breast cancer cases and being the most lethal breast cancer subtype t...
关键词：BREAST cancer clinical 
Disentangling the effects of PTSD from Gulf War Illness in male veterans via a systems‑wide analysis of immune cell,cytokine,and symptom measures
《Military Medical Research》2025年第1期1-15,共15页Esha Sultana Nandan Shastry Rishabh Kasarla Jacob Hardy Fanny Collado Kristina Aenlle Maria Abreu Emily Sisson Kimberly Sullivan Nancy Klimas Travis J.A.Craddock 
suppor ted by the US Depar tment of Defense Congressionally Directed Medical Research Program (CDMRP)awards (http://cdmrp.army.mil/) W81XWH-16-1-0632 (Craddock PI),W81XWH-16-1-0552 (Craddock PI),W81XWH-18-1-0549 (Sullivan PI),W81XWH-13-2-0072 (Sullivan PI),and W81XWH-09-2-0071 (Klimas PI);a Veterans Affairs Merit Award (4987.69) to Dr.Nancy Klimas。
Background:One-third of veterans returning from the 1990–1991 Gulf War reported a myriad of symptoms including cognitive dysfunction,skin rashes,musculoskeletal discomfort,and fatigue.This symptom cluster is now refe...
关键词：Gulf War Illness Post-traumatic stress disorder Cytokine signalling Flow cytometry Correlation networks Complete blood count SUBTYPING Trauma Symptom presentation 
Factor analysis and subtyping significance of CTNNB1 gene mutation detection in adamantinomatous craniopharyngioma
《Genes & Diseases》2024年第6期69-72,共4页Huarong Zhang Chaohu Wang Jun Fan Rongrong Guo Qianchao Zhu Jun Pan Junxiang Peng Zhiyong Wu Songtao Qi Yi Liu 
supported by grants from the National Natural Science Foundation of China (No.82103033,82204456,82002646);the President Foundation of Nanfang Hospital,Southern Medical University (No.2022A002,2022B024).
Craniopharyngioma(CP)is a rare,histologically benign tumor located in the sellar region which is defined as a grade I tumor by the World Health Organization(WHO)classification.1 There are mainly two different clinicop...
关键词：CLASSIFICATION DIAGNOSIS inoma 
Comprehensive multi-omics profiling identifies novel molecular subtypes of pancreatic ductal adenocarcinoma
《Genes & Diseases》2024年第6期315-330,共16页Xing Wang Jinshou Yang Bo Ren Gang Yang Xiaohong Liu Ruiling Xiao Jie Ren Feihan Zhou Lei You Yupei Zhao 
supported by the National Natural Science Foundation of China (No.81972321,82273455to L.Y.);CAMS Innovation Fund for Medical Sciences (CIFMS) (No.2021-I2M-1-002 to Y.Z.);the National High Level Hospital Clinical Research Funding (China) (No.2022-PUMCH-D-001);the National Multidisciplinary Cooperative Diagnosissand Treatment Capacity Building Project for Major Diseases (China).
Pancreatic cancer,a highly fatal malignancy,is predicted to rank as the second leading cause of cancer-related death in the next decade.This highlights the urgent need for new insights into personalized diagnosis and ...
关键词：Molecular characterization Molecular subtyping Multi-omics Pancreatic cancer Precision medicine 
Evolving molecular subtyping of breast cancer advances precision treatment
《Cancer Biology & Medicine》2024年第9期731-739,共9页Rui Shan Lei-Jie Dai Zhi-Ming Shao Yi-Zhou Jiang 
Breast cancer is the second most prevalent cancer globally.In 2022,approximately 2.3 million newly diagnosed cases of female breast cancer occurred worldwide,and more than 665 thousand people lost their lives to this ...
关键词：BREAST cancer BREAST 
Hierarchical learning of gastric cancer molecular subtypes by integrating multi-modal DNA-level omics data and clinical stratification
《Quantitative Biology》2024年第2期182-196,共15页Binyu Yang Siying Liu Jiemin Xie Xi Tang Pan Guan Yifan Zhu Xuemei Liu Yunhui Xiong Zuli Yang Weiyao Li Yonghua Wang Wen Chen Qingjiao Li Li C.Xia 
Guangdong Basic and Applied Basic Research Foundation,Grant/Award Number:2022A1515-011426;National Natural Science Foundation of China,Grant/Award Numbers:61873027,32000466;Shenzhen Science and Technology Program,Grant/Award Number:RCBS20200714114909234。
Molecular subtyping of gastric cancer(GC)aims to comprehend its genetic landscape.However,the efficacy of current subtyping methods is hampered by their mixed use of molecular features,a lack of strategy optimization,...
关键词：DNA alterations gastric cancer hierarchical classification molecular subtyping multi-omics 
Metabolic dysfunction-associated steatotic liver disease heterogeneity: Need of subtyping被引量：1
《World Journal of Gastrointestinal Pathophysiology》2024年第2期1-14,共14页Shahid Habib 
Metabolic dysfunction-associated steatotic liver disease(MASLD)is a widespread global disease with significant health burden.Unhealthy lifestyle,obesity,diabetes mellitus(DM),insulin resistance,and genetics have been ...
关键词：Metabolic dysfunctions-associated steatotic liver disease Visceral obesity GENETICS Diabetes Insulin resistance 
An overview of multiomics:a powerful tool applied in cancer molecular subtyping for cancer therapy被引量：1
《Malignancy Spectrum》2024年第1期15-29,共15页Yazhu Zou Zitong Zhao Yongmei Song 
National Natural Science Foundation of China(82173332).
During the process of carcinogenesis and tumor progression,various molecular alternations occur in different omics levels.In recent years,multiomics approaches including genomics,epigenetics,transcriptomics,proteomics...
关键词：multiomics cancer molecular subtyping cancer therapy single-cell omics spatial omics 
Machine-learning-based head impact subtyping based on the spectral densities of the measurable head kinematics被引量：1
《Journal of Sport and Health Science》2023年第5期619-629,F0003,共12页Xianghao Zhan Yiheng Li Yuzhe Liu Nicholas J.Cecchi Samuel J.Raymond Zhou Zhou Hossein Vahid Alizadeh Jesse Ruan Saeed Barbat Stephen Tiernan Olivier Gevaert Michael M.Zeineh Gerald A.Grant David B.Camarillo 
supported by the Pac-12 Conference’s Student-Athlete Health and Well-Being Initiative,the National Institutes of Health (R24NS098518);Stanford Department of Bioengineering。
Background:Traumatic brain injury can be caused by head impacts,but many brain injury risk estimation models are not equally accurate across the variety of impacts that patients may undergo,and the characteristics of ...
关键词：Classification Contact sports Head impacts Impact kinematics Traumatic brain injuryTagedAPTARAEnd 
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