相关期刊:《Chinese Medical Journal》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Genes & Diseases》《World Journal of Clinical Cases》更多>>
BACKGROUND Hypophysitis induced by programmed cell death 1 protein(PD-1)immune checkpoint inhibitors is rare and poorly described.We report three patients with non-small cell lung cancer who developed hypophysitis aft...
Supported by National Key R&D Program of China,No.2019YFC0120602;Clinical Research Plan of SHDC,No.SHDC2020CR3020A;Research Startup Fund of Huashan Hospital,Fudan University,No.2021QD035;Shanghai Municipal Commission of Science and Technology,No.22S31905300;Greater Bay Area Institute of Precision Medicine(Guangzhou),No.KCH2310094。
BACKGROUND Immunoglobin G4(IgG4)-related hypophysitis(IgG4-RH)is a rare form of IgG4-related disease(IgG4-RD),which often manifests as a single organ disease and is easily misdiagnosed as a pituitary tumor clinically ...
This review is supported by NICHD/NIH K08 HD070957.
Immune checkpoint inhibition against advance malignancies was named breakthrough discovery by the science magazine in 2013.In numerous clinical studies,monoclonal antibodies against the immune checkpoints,CTLA4,PD1 an...
Background:Although primary hypophysitis is not uncommon,a granulomatous etiology of hypophysitis is relatively rare.Radiological and diagnostic characteristics of several isolated cases have been described to date.Ho...
A 39-year-old woman consulted in the postpartum period because of agalactia, polyuria, polydipsia, and headache and decreased visual acuity. The initial analysis was compatible with a panhypopituitarism. The magnetic ...
Gynecomastia, characterized by the growth of breast glandular tissue in boys, is occasionally seen inclinics. This growth can manifest at any age, but 40% of cases present in adolescent boys. Even though gynecomastia ...
Granulomatous hypophysitis (GRH) is extremely rare and commonly presents with chronic inflammatory of the enlarged pituitary gland. In our study, 66-year-old and 57-year-old women, both Chinese, were diagnosed with ...