DEIODINASE

作品数：8被引量：23H指数：2
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相关领域：医药卫生农业科学更多>>
相关作者：那平王学思更多>>
相关机构：重庆医科大学天津大学更多>>
相关期刊：《Chinese Medical Sciences Journal》《Chinese Medical Journal》《Chemical Research in Chinese Universities》《Journal of Oceanology and Limnology》更多>>
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Developmental thyroid hormone action on pro-opiomelanocortin-expressing cells programs hypothalamic BMPR1A depletion and brown fat activation
《Journal of Molecular Cell Biology》2022年第9期54-67,共14页Zhaofei Wu M.Elena Martinez Victoria DeMambro Marie Francois Arturo Hernandez 
We are grateful for the technical support of the Molecular Phenotyping,Histopathology and Histomorphometry,Confocal Microscopy,and Physiology Core facilities at MaineHealth Institute for Research.These core facilities are supported by grants P30GM106391,U54GM115516,and P20GM121301 from the National Institute of General Medical Sciences;This work was supported by grant DK095908(to A.H.)from the National Institute of Diabetes,Digestive and Kidney Diseases,National Institutes of Health,USA.
Thyroid hormone excess secondary to global type 3 deiodinase(DIO3)deficiency leads to increased locomotor activity and reduced adiposity,but also to concurrent alterations in parameters of the leptin-melanocortin syst...
关键词：thyroid hormone type 3 deiodinase(DIO3) bone morphogenetic receptor 1a(BMPR1A) pro-opiomelanocortin(POMC) HYPERPHAGIA brown adipose tissue CORTICOSTERONE 
Biological Functions of Selenoprotein Iodothyronine Deiodinase and its Expression in Osteoarthritis被引量：2
《Chinese Medical Sciences Journal》2022年第2期142-150,共9页Xiaomei Ren Li Zhang Bao Xin Qiling Liu Wenwen Qian Rongqiang Zhang 
supported by Science and Technology Programme of Shaanxi Province(2020SF-076);Science Research Project of Education Department of Shaanxi Province(19JS015);Healthcare Research Fund from Health Commission of Shaanxi Province(2018A019).
Objective Iodothyronine deiodinases(DIOs)are important selenoproteins that play a key role in the bone and joint diseases.Osteoarthritis(OA)is the most prevalent joint disease especially in elders.This bioinformatic a...
关键词：SELENOPROTEIN iodothyronine deiodinase OSTEOARTHRITIS 
The transcription of iodothyronine deiodinase genes is regulated by thyroid hormone receptor in the Pacific oyster Crassostrea gigas被引量：1
《Journal of Oceanology and Limnology》2019年第4期1317-1323,共7页HUANG Wen XU Fei LI Li QUE Huayong ZHANG Guofan 
Supported by the National Natural Science Foundation of China(No.31372515);the Guangxi Natural Science Foundation(Nos.2016GXNSFBA380028,2017GXNSFAA198196);the China Agriculture Research System(No.CARS-49)
Thyroid hormones (THs) are indispensable for each phyla in Chordata, while their functions in the non-chordate invertebrates are indistinct. Studies on the TH system in non-chordate invertebrates are important for und...
关键词：iodothyronine DEIODINASE MOLLUSK THYROID hormone (TH) TH responsive elements 
Iodothyronine deiodinase gene analysis of the Pacific oyster Crassostrea gigas reveals possible conservation of thyroid hormone feedback regulation mechanism in mollusks被引量：1
《Chinese Journal of Oceanology and Limnology》2015年第4期997-1006,共10页黄雯 许飞 曲涛 李莉 阙华勇 张国范 
Supported by the National Natural Science Foundation of China(Nos.31372515,31402285);the National Basic Research Program of China(973 Program)(No.2010CB126401);the National High Technology Research and Development Program(863 Program)(No.2012AA10A405)
Iodothyronine deiodinase catalyzes the initiation and termination of thyroid hormones(THs) effects, and plays a central role in the regulation of thyroid hormone level in vertebrates. In non-chordate invertebrates, on...
关键词：iodothyronine deiodinase Crassostrea gigas thyroid hormone （TH） CLONE expression analysis 
Selection,Expression and Purification of Human Abzyme Containing Selenium with Type Ⅰ Thyroxine Deiodinase Activity被引量：2
《Chemical Research in Chinese Universities》2011年第4期619-622,共4页LIN Feng LIU Lan-ying NI Jia-zuan 
Supported by the Basic Science Research Fund of Jilin University,China(No.200903259)
Single-chain fragment variable（ScFv） antibodies with the substrate binding sites were obtained by repetitive selections from a semi-synthetic phage display antibody library against two haptens——thyroxine（T4） and...
关键词：Phage antibody library HUMANIZATION SELENIUM Catalytic antibody SELECTION 
Type 1 iodothyronine deiodinase activity and mRNA expression in rat thyroid tissue with different iodine intakes被引量：12
《Chinese Medical Journal》2006年第22期1899-1903,共5页WANG Kun SUN Yi-na LIU Jia-yu YAN Yu-qin CHEN Zu-pei 
This study was supported by grants from the National Nature Science Foundation of China (No.30230330) and Tianjin Technology Development Project (No.05YFGDSF02700).
Background Type 1 deiodinase （D1） plays an important role in the metabolism of thyroid hormone and has close relationship with thyroid function. In this study we explore the effects of iodine intake on D1 activity a...
关键词：Type 1 deiodinase iodine deficiency iodine excess thyroid hormone 
Effect of Selenium Supplementation on Activity and mRNA Expression of Type 1 Deiodinase in Mice With Excessive Iodine Intake被引量：5
《Biomedical and Environmental Sciences》2006年第4期302-308,共7页XUE-FENG YANG XIAO-HUI HOU JIAN XW HUAI-LAN GUO CHEN-JIANG YING XIAO-YI CHEN XIU-FA SUN 
This work was supported by the National Science Foundation of China (NSFC) (No. 30230330).
Objective To investigate the effect of selenium supplementation on the selenium status and selenoenzyme, especially the activity and mRNA expression of type 1 deiodinase （D1） in mice with excessive iodine （EI） int...
关键词：Excessive iodine SELENIUM Glutathione peroxidase Type 1 deiodinase 
Effect of Dietary Selenium on the Activities of Glutathione Peroxidase and Deiodinase in Rat Liver
《Biomedical and Environmental Sciences》1999年第1期79-79,共1页ZhangZaixiang TianYuan 等 
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