云南高校图书馆联盟文献共享服务平台- ANTIVENOM

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In Silico Screening of Potential Inhibitors against dPLA2 from Named Chinese Herbs for Identification of Compounds with Antivenom Effects Due to Deinagkistrodon acutus Snake Bites: 《American Journal of Molecular Biology》2024年第3期107-125,共19页Xingyang Xiao Mengyi Lai Zechang Rao Jianzhong Huang Yiwei Xie Hongbin Zhang; Phospholipase A2 (PLA2) is the key enzyme to the venom from Deinagkistrodon acutus which is one of the highly venomous snakes in China. In addition to being a catalyst for the hydrolysis of phospholipases A2 from snak...; 关键词：Chinese Herbal Medicine Phospholipase A2 Inhibitor Molecular Docking Molecular Mechanism

Severe Allergic Reaction Following Administration of Antivenom Serum for Snakebite: A Case Report from Togo: 《Case Reports in Clinical Medicine》2024年第8期297-303,共7页Awèréou Kotosso Lidaw Deassoua Bawe Akouda Akessiwe Patassi Lampouguini Nebona Cici Amouzou Esso-Essinam Félix Pissang Bawoubadi Abaltou Gnimdou Tchamdja Magnoudewa Poko Hassimou Bramah Majesté Ihou Wateba; Background: Ophidian envenomation is common in Sub-Saharan Africa, and its management is hampered by the lack of access to healthcare services in rural areas, in particular the availability and appropriate use of anti...; 关键词：SNAKEBITE ANTIVENOM Allergic Reaction Sub-Saharan Africa TOGO

Synergistic effect of flavonoids combined with antivenom on neutralisation of Naja naja venom: 《Asian Pacific Journal of Tropical Biomedicine》2021年第7期298-307,共10页Srimathi Raghavan Gurunathan Jayaraman; Objective:To evaluate the neutralizing effects of flavonoids on snake venom toxicity by stand-alone and combinatorial approaches.Methods:Synthetic flavonoids were assessed,either individually or in combination with an...; 关键词：Flavonoid Anti-venom Snake bite Combinatorial SYNERGISTIC Naja naja

Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms被引量：3: 《Acta Pharmaceutica Sinica B》2020年第10期1835-1845,共11页Chunfang Xie Julien Slagboom Laura-Oana Albulescu Govert W.Somsen Freek J.Vonk Nicholas R.Casewell Jeroen Kool; funded by a China Scholarship Council(CSC)fellowship(201706250035);support from a UK Medical Research Council(MRC)Research Grant(MR/S00016X/1);Confidence in Concept Award(Ci C19017,UK);a Sir Henry Dale Fellowship(200517/Z/16/Z,UK)jointly funded by the Wellcome Trust and Royal Society; Repurposing small molecule drugs and drug candidates is considered as a promising approach to revolutionise the treatment of snakebite envenoming.In this study,we investigated the inhibiting effects of the small molec...; 关键词：SNAKEBITE ANTIVENOM Varespladib MARIMASTAT Dimercaprol CHELATORS Nanofractionation

Determination of median effective dose(ED_(50)) of scorpion antivenom against scorpion envenomation using a newly developed formula: 《Animal Models and Experimental Medicine》2018年第3期228-234,共7页Saganuwan Alhaji Saganuwan; Background: About 50 species of scorpions cause fatal scorpionism worldwide.Most of these are members of the Buthidae family, and include, among others,Mesobuthus eupeus, Androctonus crassicauda, Leiurus abdullahbayra...; 关键词：ANTIVENOM ED50 human equivalent dose LD50 SCORPION VENOM

Increased Efficacy of Antivenom Combined with Hyperbaric Oxygen on Deinagkistrodon acutus Envenomation in Adult Rats被引量：9: 《Chinese Medical Journal》2018年第3期323-329,共7页Mo Li Zhi-Hui Xie An-Yong Yu Dong-Po He; This study was supported by grants from the Science and Technology Foundation of Guizhou Province （No. SY [2013]3067） and National Natural Science Foundation of China （No. 81560217）.; Background：Snakebites are a neglected threat to global human health with a high morbidity rate.The present study explored the efficacy of antivenom with hyperbaric oxygen （HBO） intervention on snakebites,which coul...; 关键词：Deinagkistrodon acutus Venom ANTIVENOM Hyperbaric Oxygenation NESTIN SNAKEBITES Subventricular Zone

Allergic reactions to antivenom in a patient bitten twice by the same snake within a month： A rare case report and literature review: 《Chinese Journal of Traumatology》2017年第5期299-302,共4页Fan-Jie Zeng Cong Chen Ming-Hua Liu; Antivenom is the most effective method currently available for the treatment of poisonous snake bite. Allergic reactions to antivenom have been reported in the past. Here we shared a case of allergic re- actions to an...; 关键词：Snake bites Antibodies Anti-snake venom serum Hypersensitivity

Pharmacological Evaluation of Hexane Fraction of Casearia gossypiosperma Briquet： Antivenom Potentiality: 《Journal of Life Sciences》2014年第4期306-315,共10页Juliana de Oliveira Soares-Silva Jhones Luiz de Oliveira José Carlos Cogo Renata Vasques da Silva Tavares Yoko Oshima-Franco; Neuromuscular junction is the main target for snakebites, which venoms act depending on the snake genus for paralyzing the prey （neurotoxicity） or for facilitating the digestion processes of the victim （myotoxicity...; 关键词：Bothrops jararacussu Casearia gossypiosperma Briquet Crotalus durissus terrificus neuromuscular junction pharmacological evaluation.

Antihaemolytic and snake venom neutralizing effect of some Indian medicinal plants: 《Asian Pacific Journal of Tropical Medicine》2011年第9期743-747,共5页Chidambaram Kumarapppan Albert Iaswanth Karpagam Kumarasunderi; Periyar College of Pharmacecutical Sciences Periyar Maniammai University,Thiruchirappalli,Tamilnadu for his constant support and providingg facilities to carry out this work successfully;King Institute of Preventive Medicine,Guindy,Chennai,is also thanked for the Naja nigricollis venom support; Objective:To validate traditional claims of usefulness of the Indian plants in management of poisonous snakebite and evaluate the antivenom properties displayed bv the alcoholic extracts of Andrographis paniculata（A....; 关键词：ANTIVENOM activity Naja nigricollis HEMOLYSIS NEUTRALIZATION INDIAN MEDICINAL plants

The theropeutic effect of JiDesheng antivenom tablets in treatment of tetanus: 《Chinese Journal of Traumatology》2000年第3期191-192,共2页陆文煜李绍洲; 关键词：JiDesheng 破伤风治疗抗动物毒素

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