CHELATORS

作品数：16被引量：29H指数：3
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相关领域：医药卫生环境科学与工程更多>>
相关期刊：《Asian Journal of Pharmaceutical Sciences》《Research》《Journal of Pancreatology》《Emerging Contaminants》更多>>
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Role of copper chelating agents: between old applications and new perspectives in neuroscience
《Neural Regeneration Research》2025年第3期751-762,共12页Rosalba Leuci Leonardo Brunetti Vincenzo Tufarelli Marco Cerini Marco Paparella Nikola Puvača Luca Piemontese 
The role of copper element has been an increasingly relevant topic in recent years in the fields of human and animal health, for both the study of new drugs and innovative food and feed supplements. This metal plays a...
关键词：agriculture Alzheimer's disease CHELATORS COPPER feed supplements MULTI-TARGET 
Synergistic interactions of assorted ameliorating agents to enhance the potential of heavy metal phytoremediation
《Stress Biology》2024年第1期600-622,共23页S.Sanjana K.Jazeel E.Janeeshma Sarath G.Nair A.M.Shackira 
provided by UGC-CSIR in the form of a Junior Research Fellowship(211610064222).
Pollution by toxic heavy metals creates a significant impact on the biotic community of the ecosystem.Nowadays,a solution to this problem is an eco-friendly approach like phytoremediation,in which plants are used to a...
关键词：CHELATORS Heavy metal Metabolomics PHYTOREMEDIATION 
Recent advances in copper homeostasis-involved tumor theranostics
《Asian Journal of Pharmaceutical Sciences》2024年第5期54-87,共34页Xinghua Ren Xinyi Luo Fuchang Wang Long Wan Xiaofan Wang Jinya Xiong Mengwei Ye Shiqiao Rui Zhu Liu Siling Wang Qinfu Zhao 
Grant from Liaoning Provincal National Nature Science Foundation of China(No.2023-MS-202)is greatly acknowledged.
As the third essential trace element in the human body,copper plays a crucial role in various physiological processes,which lays the foundation for its broad applications in cancer treatments.The overview of copper,in...
关键词：Copper homeostasis Tumor theranostics Cu-based nanoparticles Cuproptosis CHELATORS 
Characteristics of patients with Wilson disease in the United States: An insurance claims database study
《World Journal of Hepatology》2024年第5期791-799,共9页Thomas Daniel-Robin Pradeep Kumar Bernard Benichou Jean-Philippe Combal 
BACKGROUND Wilson disease(WD)is a progressive,potentially fatal degenerative disease affecting the liver and central nervous system.Given its low prevalence,collecting data on large cohorts of patients with WD is chal...
关键词：Wilson disease MORTALITY TREATMENT Copper chelators Zinc acetate United States 
Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer’s Disease被引量：1
《Research》2024年第1期687-706,共20页Qianqian Huang Chaoqing Jiang Xue Xia Yufan Wang Chenxing Yan Xiaorong Wang Ting Lei Xiaotong Yang Wenqin Yang Guo Cheng Huile Gao 
the Research and Development Program of Science and Technology Department of Sichuan Province(2022JDJQ0050);111 Project(B18035);the Fundamental of Research Funds for the Central Universities.
Inflammatory responses,manifested in excessive oxidative stress and microglia overactivation,together with metal ion-triggered amyloid-beta(Aβ)deposition,are critical hallmarks of Alzheimer’s disease(AD).The intrica...
关键词：oxidative aggregation CHELATING 
Chelators to assist the high dispersion of Ni_(2)P particles over mesoporous silica nanospheres for hydrogenating reaction
《Petroleum Science》2023年第3期1895-1902,共8页Di Hu En-Hua Wang Ao-Cheng Wang Ai-Jun Duan 
supported by the National Natural Science Foundation of China(No.21878330);Key Research and Development Program of Ministry of Science and Technology of China(No.2019YFC1907602);Scientific Research and Technology Development Program of China National Petroleum Corporation(2020B-2116).
NizP supported catalysts exhibit high catalytic activities in hydrogenation reaction,of which the particle sizes of Ni_(2)P active phases are the key influential factor.This research focus on the effect of chelators o...
关键词：Wrinkle silica nanoparticles CHELATORS Ni_(2)P supported catalysts Naphthalene hydrogenation 
Impact of antagonist peptides and chelators on the diagnostic performance of PET/CT using gallium-68-labeled somatostatin receptor antagonists
《Journal of Pancreatology》2023年第1期28-33,共6页Haiqun Xing Wenjia Zhu Yuejuan Cheng Qiao Yang Ru Jia Hong Zhao Chunmei Bai Li Huo Wenming Wu 
National Natural Science Foundation of China(No. 82071967);CAMS initiative for innovative medicine(No. CAMS-2018-I2M-3-001);National Key Research and Development Program of China(No. 2016YFC0901500);Center for Rare Diseases Research, Chinese Academy of Medical Sciences, Beijing, China(No. 2016ZX310174-4)。
Objective: Different SSTR2 antagonists have been developed. This study aims to evaluate the impact of different peptides and chelators on the diagnostic performance of SSTR2 antagonists in well-differentiated NETs.Met...
关键词：-DOTA-LM3 68Ga-NODAGA-JR11 68Ga-NODAGA-LM3 Neuroendocrine tumor Somatostatin receptor antagonist 
Impact of antagonist peptides and chelators on the diagnostic performance of PET/CT using gallium-68 labeled somatostatin receptor antagonists
《Journal of Pancreatology》2022年第3期15-39,共25页Haiqun Xing Wenjia Zhu Yuejuan Cheng Qiao Yang Ru Jia Hong Zhao Chunmei Bai Li Huo Wenming Wu 
This work was sponsored in part by the National Natural Science Foundation of China(No.82071967);CAMS initiative for innovative medicine(No.CAMS-2018-I2M-3-001);National Key Research and Development Program of China(No.2016YFC0901500);Center for Rare Diseases Research,Chinese Academy of Medical Sciences,Beijing,China(No.2016ZX310174-4)。
Objective:Different SSTR2 antagonists have been developed.This study aims to evaluate the impact of different peptides and chelators on the diagnostic performance of SSTR2 antagonists in well-differentiated NETs.Metho...
关键词：Somatostatin receptor antagonist 68Ga-NODAGA-LM3 68Ga-DOTA-LM3 68Ga-NODAGA-JR11 neuroendocrine tumor 
Emerging contaminants: Evaluation of degradable chelators towards enhancing cadmium phytoextraction efficiency of bioenergy crop grown on polluted soil被引量：3
《Emerging Contaminants》2021年第1期139-148,共10页Segun O.Oladele Blessing B.Oladele Rasheedat Ajala Bukola F.Dada 
Exogenous application of chelators towards enhancing heavy metals extraction efficiency of bioenergy crop has received considerable attention in recent time.However,little is known about optimal application rate,compa...
关键词：PHYTOEXTRACTION Antioxidant enzymes Photosynthetic rate Stress tolerance Cadmium speciation 
Neutralising effects of small molecule toxin inhibitors on nanofractionated coagulopathic Crotalinae snake venoms被引量：3
《Acta Pharmaceutica Sinica B》2020年第10期1835-1845,共11页Chunfang Xie Julien Slagboom Laura-Oana Albulescu Govert W.Somsen Freek J.Vonk Nicholas R.Casewell Jeroen Kool 
funded by a China Scholarship Council(CSC)fellowship(201706250035);support from a UK Medical Research Council(MRC)Research Grant(MR/S00016X/1);Confidence in Concept Award(Ci C19017,UK);a Sir Henry Dale Fellowship(200517/Z/16/Z,UK)jointly funded by the Wellcome Trust and Royal Society
Repurposing small molecule drugs and drug candidates is considered as a promising approach to revolutionise the treatment of snakebite envenoming.In this study,we investigated the inhibiting effects of the small molec...
关键词：SNAKEBITE ANTIVENOM Varespladib MARIMASTAT Dimercaprol CHELATORS Nanofractionation 
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