PROLIPOSOMES

作品数：3被引量：35H指数：2
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相关领域：医药卫生化学工程更多>>
相关作者：张彦卓任君刚李津明更多>>
相关机构：哈尔滨商业大学北京正大绿洲医药科技有限公司沈阳药科大学更多>>
相关期刊：《Acta Pharmacologica Sinica》《Journal of Chinese Pharmaceutical Sciences》《Acta Pharmaceutica Sinica B》更多>>
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Insoluble drug delivery strategies: review of recent advances and business prospects被引量：30
《Acta Pharmaceutica Sinica B》2015年第5期442-453,共12页Sandeep Kalepu Vijaykumar Nekkanti 
The emerging trends in the combinatorial chemistry and drug design have led to the development of drug candidates with greater lipophilicity, high molecular weight and poor water solubility. Majority of the failures i...
关键词：BIOAVAILABILITY COCRYSTALS SOLUBILITY Inclusion complexation Nanoparticles Self-emulsifying formulations PROLIPOSOMES 
Proliposomes for oral delivery of dehydrosilymarin： preparation and evaluation in vitro and in vivo被引量：5
《Acta Pharmacologica Sinica》2011年第7期973-980,共8页Chang CHU Shan-shan TONG Ying XU Li WANG Min FU Yan-ru GE Jiang-nan YU Xi-ming XU 
Aim： To formulate proliposomes with a polyphase dispersed system composed of soybean phospholipids, cholesterol, isopropyl myristate and sodium cholate to improve the oral bioavailability of dehydrosilymarin, an oxid...
关键词：SILYMARIN dehydrosilymarin PROLIPOSOMES oral bioavailability PHARMACOKINETICS 
Preparation of stealthy etoposide proliposomes and the pharmacokinetics in rabbits
《Journal of Chinese Pharmaceutical Sciences》2008年第4期303-308,共6页李津明 张彦卓 任君刚 曲韵志 
Research Projects of Heilongjiang Science and Technology Department (Grant No.GC05C31601).
The objectives of the present study were to prepare stealthy etoposide proliposomes and study the pharmacokinetics in rabbits. Blank stealthy liposomes were prepared by film dispersion method. Stealthy etoposide lipos...
关键词：Etoposide  Stealthy proliposomes High performance liquid chromatography PHARMACOKINETICS 
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