PEPSINOGEN

作品数：40被引量：369H指数：12
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相关领域：医药卫生更多>>
相关作者：刘经纬袁媛刘礼剑李晓红陈铁军更多>>
相关机构：中国医学科学院北京协和医学院北京中医药大学中国医科大学附属第一医院西南医科大学附属中医医院更多>>
相关期刊：《World Journal of Gastrointestinal Endoscopy》《Journal of Oceanology and Limnology》《Journal of Rare Earths》《诊断病理学杂志》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划上海市教育委员会重点学科基金更多>>
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Value of serum pepsinogen ratio screening for early gastric cancer and precancerous lesions in Youcheng area
《World Journal of Gastrointestinal Surgery》2024年第12期3729-3736,共8页Xue Han Wei Yu 
BACKGROUND The 5-year survival rate of patients with advanced gastric cancer remains extremely low(<15%),whereas the 5-year survival rate of patients with early gastric cancer(EGC)is>90%.Consequently,strengthening the...
关键词：PEPSINOGEN Pepsinogen ratio Early gastric cancer Precancerous lesions Screening value 
Postprandial gastrin-17 level is a useful dynamic marker for atrophic gastritis
《World Journal of Gastrointestinal Endoscopy》2024年第11期623-626,共4页Huck-Joo Tan Eunice Zhi-Yi Tan 
Atrophic gastritis and intestinal metaplasia may progress to gastric malignancy.Non-invasive serum biomarkers have been extensively studied and proven to be useful as a screening tool to stratify risk and identify pat...
关键词：Atrophic gastritis PEPSINOGEN GASTRIN-17 Gastric cancer Biomarkers 
贲门胃底腺黏膜型腺癌1例
《诊断病理学杂志》2024年第9期915-917,共3页唐丹 肖华亮 马强 
胃底腺黏膜型腺癌(GA-FGM)是一种新型的胃腺癌,具有向胃底腺及胃小凹上皮分化的特点,比较罕见,目前国内外文献报道病例不超过30例,其中国内报道仅有2例;现报道1例发生于65岁男性患者胃贲门部的病例,通过对组织学形态、免疫表型的阐述及...
关键词：胃底腺黏膜型腺癌 贲门 MUC6 pepsinogen-Ⅰ H+/K+-ATPase 
Clinical value of serum pepsinogen in the diagnosis and treatment of gastric diseases被引量：5
《World Journal of Gastrointestinal Oncology》2023年第7期1174-1181,共8页Yuan Qin Jia-Xin Geng Biao Huang 
Supported by the National Natural Science Foundation of China,No.82172336;“Pioneer”and“Leading Goose”R&D Program of Zhejiang,No.2022C03118 and No.2023C03075;Natural Science Foundation of Zhejiang Province,No.LQ23H050005;Scientific Research Project of Zhejiang Provincial Education Department,No.Y202250731.
Pepsinogen,secreted from the gastric mucosa,is the precursor of pepsin.It is categorized as pepsinogen 1 and pepsinogen 2 based on its immunogenicity.The pepsinogen content that can enter the blood circulation through...
关键词：Pepsinogen 1 Pepsinogen 2 Gastric diseases Serological marker Serological biopsy 
The ontogeny of acidic digestive tract in larval turbot Scophthalmus maximus based on H+/K+-ATPase and pepsinogen
《Journal of Oceanology and Limnology》2023年第3期1100-1108,共9页Yanfeng WANG Shulan LIU Teng GUO Shihong XU Qinghua LIU Zhizhong XIAO Daoyuan MA Jun LI Liang CHI 
Supported by the National Key Research and Development Program(No.2018YFD0901204);the Key Special Project for Introduced Talents Team of Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou)(No.GML2019ZD0402);the Major Agricultural Application Technology Innovation Project of Shandong Province(No.SD2019YY011);the Qingdao National Laboratory for Marine Science and Technology(No.2018SDKJ0502-2);the China Agriculture Research System(No.CARS-47),the Major Science and Technology for Scientific and Technological Innovation Projects(Shandong)(No.2019JZZY020710);the STS Project(Nos.KFZD-SW-106,ZSSD-019,2017T3017,2019T3022)。
Acidic digestion is an important digestive process of marine fish.In fish stomach,two enzymes are involved in the secretion of hydrochloric acid(HCl)and proteomic digestion:H^(+)/K^(+)-ATPase and pepsinogen.However,th...
关键词：TURBOT Scophthalmus maximus acidic digestion H+/K+-ATPase PEPSINOGEN 
Family-based Helicobacter pylori infection status and transmission pattern in central China,and its clinical implications for related disease prevention被引量：21
《World Journal of Gastroenterology》2022年第28期3706-3719,共14页Xue-Chun Yu Qiao-Qiao Shao Jing Ma Miao Yu Chen Zhang Lei Lei Yang Zhou Wen-Chao Chen Wei Zhang Xin-Hui Fang Yuan-Zeng Zhu Gang Wu Xue-Mei Wang Shuang-Yin Han Pei-Chun Sun Song-Ze Ding 
National Natural Science Foundation of China,No.U1604174;Henan Provincial Government-Health and Family Planning Commission,No.20170123 and No.SBGJ202002004;Henan Provincial Government-Health and Family Planning Commission Research Innovative Talents Project,No.51282
BACKGROUND Helicobacter pylori(H.pylori)has characteristics of family cluster infection;however,its family-based infection status,related factors,and transmission pattern in central China,a high-risk area for H.pylori...
关键词：Helicobacter pylori Atrophic gastritis Family clustering infection Gastric cancer GASTRIN PEPSINOGEN 
Role of magnifying narrow-band imaging endoscopy for diagnosis of Helicobacter pylori infection and gastric precancerous conditions:Few issues
《World Journal of Gastroenterology》2022年第15期1601-1603,共3页Saroj Kanta Sahu Ayaskanta Singh 
Standard endoscopy with biopsy and narrow-band imaging with guided biopsy are techniques for the detection of Helicobacter pylori(H.pylori)-related gastritis and precancerous lesions.In this study,the authors compared...
关键词：Standard endoscopy Magnified narrow band imaging Helicobacter pylori Atrophic gastritis Intestinal metaplasia PEPSINOGEN 
Inverse correlation between gastroesophageal reflux disease and atrophic gastritis assessed by endoscopy and serology被引量：6
《World Journal of Gastroenterology》2022年第8期853-867,共15页Yoo Min Han Su Jin Chung Seokha Yoo Jong In Yang Ji Min Choi Jooyoung Lee Joo Sung Kim 
BACKGROUND Helicobacter pylori(H.pylori)infection is known to prevent the occurrence of gastroesophageal reflux disease(GERD)by inducing gastric mucosal atrophy.However,little is known about the relationship between a...
关键词：Gastroesophageal reflux disease Reflux esophagitis Helicobacter pylori Atrophic gastritis PEPSINOGEN 
Serum gastrin-17 concentration for prediction of upper gastrointestinal tract bleeding risk among peptic ulcer patients被引量：11
《World Journal of Clinical Cases》2021年第35期10948-10955,共8页Jun-Xian Wang Yu-Ping Cao Peng Su Wei He Xiao-Ping Li Ya-Meng Zhu 
the Second People's Hospital of Anhui Province,Institutional Review Board(Approval No.2015-036).
BACKGROUND Serum gastrin-17(G-17),pepsinogen I(PGI),and pepsinogen II(PGII)concentrations regulate gastric acid secretion,and hypersecretion of gastric acid increases the risks of peptic ulcer and upper gastrointestin...
关键词：Peptic ulcer Upper gastrointestinal bleeding GASTRIN PEPSINOGEN Receiver operating characteristic curve 
Association of serum pepsinogen with degree of gastric mucosal atrophy in an asymptomatic population被引量：4
《World Journal of Clinical Cases》2021年第31期9431-9439,共9页Hao-Lei Cai Yu-Ling Tong 
Supported by National Natural Science Foundation of China,No.71804161,No.72074188。
BACKGROUND Atrophic gastritis is a precancerous lesion of the stomach.It has been reported that pepsinogen(PG)can reflect the morphology and function of the gastric mucosa,and it is therefore used as a marker for the ...
关键词：PEPSINOGEN Helicobacter pylori Operative Link for Gastritis Assessment Atrophic gastritis Gastric mucosal atrophy BIOMARKER 
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