SIGNALTRANSDUCTION

作品数：7被引量：49H指数：4
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相关领域：生物学医药卫生更多>>
相关期刊：《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Signal Transduction and Targeted Therapy》《Molecular Plant》更多>>
相关基金：国家自然科学基金北京市自然科学基金更多>>
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Jinghua Weikang capsule protects against Helicobacter pylori-induced inflammatory responses via the nuclear factor-kappa B signaling pathway被引量：4
《Journal of Traditional Chinese Medicine》2018年第3期366-372,共7页Shi Zongming Ye Hui Yu Jing Cheng Hong Li Jiang Zhang Xuezhi 
Supported by Grants from the National Natural Science Foundation of China Project:Research on the Anti-inflammatory Effects and Mechanism of Jinghua Weikang Capsule and Its Ingredients Against H.pylori Infected Gastritis through TLR4-NFKB-cytokine Pathway in Mice(No.81473474);Natural Science Foundation of Beijing Project:the Effectand Mechanism of Jinghua Weikang Capsule Inhibiting the Adhesion Effect of H.pylori(No.7172220)
OBJECTIVE: To investigate the inhibitory effect of Jinghua Weikang capsule(JWC) on gastric inflammation induced by Helicobacter pylori(H. pylori)via the nuclear factor-kappa B(NF-κB) signaling pathway in Kunming mice...
关键词：HELICOBACTER PYLORI NF-KAPPA B SIGNALTRANSDUCTION Jinghua Weikang CAPSULE 
Let’s talk about Secs: Sec61, Sec62 and Sec63 in signaltransduction, oncology and personalized medicine被引量：14
《Signal Transduction and Targeted Therapy》2017年第1期229-238,共10页Maximilian Linxweiler Bernhard Schick Richard Zimmermann 
The heterotrimeric Sec61 complex and the dimeric Sec62/Sec63 complex are located in the membrane of the human endoplasmic reticulum(ER)and play a central role in translocation of nascent and newly synthesized precurso...
关键词：TRANSPORT SIGNAL CANCER 
Roles of Arabidopsis Patatin-Related Phospholipases A in Root Development Are Related to Auxin Responses and Phosphate Deficiency被引量：7
《Molecular Plant》2010年第3期524-538,共15页Steffen Rietz Georgi Dermendjiev Esther Oppermann Fikadu Getah Tafesse Yunus Effendi Andre Holk Jane E. Parker Markus Teige Gunther F.E. Scherer 
Phospholipase A enzymes cleave phospho- and galactolipids to generate free fatty acids and lysolipids that function in animal and plant hormone signaling. Here, we describe three Arabidopsis patatin-related phospholip...
关键词：Abiotic/environmental stress hormonal regulation protein phosphorylation/dephosphorylation SIGNALTRANSDUCTION gene regulation Arabidopsis. 
Ethylene Controls Autophosphorylation of the Histidine Kinase Domain in Ethylene Receptor ETR1被引量：8
《Molecular Plant》2008年第2期380-387,共8页Jan Voet-van-Vormizeele Georg Groth 
Perception of the phytohormone ethylene is accomplished by a small family of integral membrane receptors. In Arabidopsis, five ethylene receptor proteins are known, including ethylene resistant I （ETR1）. The hydroph...
关键词：ethylene pathway phytohormone receptor membrane protein two-component system SIGNALTRANSDUCTION Arabidopsis thaliana 
Fibrinogen interaction of CHO cells expressing chimeric αⅡb/αvβ3 integrin
《Acta Pharmacologica Sinica》2008年第2期204-210,共7页Juan-juan CHEN Xiao-yu SU Xiao-dong XI Li-ping LIN Jian DING He LU 
Aim： The molecular mechanisms of the affinity regulation of αvβ3 integrin are important in tumor development, wound repairing, and angiogenesis. It has been established that the cytoplasmic domains of αvβ3 integr...
关键词：INTEGRIN cell adhesion FIBRINOGEN SIGNALTRANSDUCTION 
Effect of BN52021 on NFκ-Bp65 expression in pancreatic tissues of rats with severe acute pancreatitis被引量：13
《World Journal of Gastroenterology》2007年第6期882-888,共7页Shi-Hai Xia Dian-Chun Fang Chun-Xiu Hu Hui-Ying Bi Yin-Zhi Yang Yao Di 
the National Natural Science Foundation of China, No. 30300465
AIM： To investigate dynamic changes and significance of expression of NF-κBp65 in pancreatic tissues of rats with severe acute pancreatitis （SAP）, as well as BN52021 effects. METHODS： Wistar male rats were random...
关键词：BN52021 PANCREATITIS NF-ΚB SIGNALTRANSDUCTION 
Activation and involvement of JNK1/2 in hydrogen peroxideinduced neurotoxicity in cultured rat cortical neurons被引量：3
《Acta Pharmacologica Sinica》2004年第5期630-636,共7页WeiWANG CanGAO Xiao-yuHOU YongLIU Yan-yanZONG Guang-yiZHANG 
The present study was supported by grants from the Educa-tion Departmental Natural Science Research Funds of JiangsuProvince of China (No 99KJB180002; 99KJD180004) and theNational Natural Science Foundation of China (No 39770177).2
AIM: To investigate the role of c-Jun N-terminal protein kinase 1 and 2 (JNK1/2) and the main signal pathway forits activation in hydrogen peroxide (H2O2) induced apoptotic-like cortical cell death. METHODS: Using th...
关键词：c-Jun N-terminal protein kinase calcium N-methylaspartate receptors hydrogen peroxide SIGNALTRANSDUCTION apoptosis cerebral cortex 
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