云南高校图书馆联盟文献共享服务平台- XENOTRANSPLANTATION

XENOTRANSPLANTATION: 作品数：77被引量：178H指数：7; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：张燕王峰朱丽华孙瑞萍余路阳更多>>; 相关机构：华中科技大学海南省农业科学院四川大学中国科学院上海生命科学研究院更多>>; 相关期刊：《Chinese Journal of Cancer Research》《Progress in Natural Science:Materials International》《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》《Animal Husbandry and Feed Science》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家教育部博士点基金更多>>

Cardiac transplantation:A review of current status and emerging innovations: 《World Journal of Transplantation》2025年第2期49-64,共16页Umashri Sundararaju Srinivas Rachoori Abdulkader Mohammad Hamrish Kumar Rajakumar; Heart transplantation(HTx)is a life-saving procedure for patients with end-stage heart failure and has undergone remarkable advancements since the first succe-ssful transplant in 1967.The introduction of cyclosporine ...; 关键词：Heart transplantation End-stage heart failure Donor selection IMMUNOSUPPRESSION Mechanical circulatory support XENOTRANSPLANTATION Regenerative medicine Surgical techniques Donor management Transplantation outcomes

The initiative for consensus and standards in pig-to-human xenotransplantation in China: 《The Innovation》2024年第6期3-4,共2页Dong Niu Yulong Yin; supported by The Key Project of Zhejiang Provincial Natural Science Foundation of China(LZ22C010003);the Scientific and Technological Innovation Leading Talents Project of Zhejiang Provincial“High-level Talents Special Support Plan”(2021R52043).; The global organ shortage is critically severe,withmany patients at risk of lifethreatening conditions due to the scarcity of suitable donor organs.Gene-edited porcine organs for human transplantation have emerged as ...; 关键词：ORGANS establishing XEN

Pig organs in humans:a forum on xenotransplantation被引量：1: 《National Science Review》2024年第10期396-403,共8页Weijie Zhao Gang Chen Lin Wang David K.C.Cooper Xuan Zhang Yifan Dai Liangxue Lai Dengke Pan; What if one of your organs,say,the kidney,the heart or the liver,deteriorates completely,and you are not lucky enough to have a human organ for transplantation?Do you want to receive an organ from a pig?That is not a ...; 关键词：ORGANS KIDNEY ENOUGH

Elimination of GGTA1,CMAH,β4GalNT2 and CIITA genes in pigs compromises human versus pig xenogeneic immune reactions: 《Animal Models and Experimental Medicine》2024年第4期584-590,共7页Jing Xu Jilong Ren Kai Xu Minghui Fang Meina Ka Fei Xu Xin Wang Jing Wang Zhiqiang Han Guihai Feng Ying Zhang Tang Hai Wei Li Zheng Hu; National Key Research and Development Program,Grant/Award Number:2019YFA0903800,2021YFA0805701,2021YFA0805905 and 2022YFA1103603;CAS Project for Young Scientists in Basic Research,Grant/Award Number:YSBR-012;STI 2030-Major Project,Grant/Award Number:2023ZD0407503;National Natural Science Foundation of China,Grant/Award Number:32071456 and 82241224;Strategic Priority Research Program of the Chinese Academy of Sciences,Grant/Award Number:XDA16030000。; Background:Pig organ xenotransplantation is a potential solution for the severe organ shortage in clinic,while immunogenic genes need to be eliminated to improve the immune compatibility between humans and pigs.Curren...; 关键词：CD4 T cell genetically edited pig immune rejection major histocompatibility complex II XENOTRANSPLANTATION

Current status and challenges of pig-to-human organ xenotransplantation: 《Science China(Life Sciences)》2024年第4期829-831,共3页Minghui Fang Yong-Guang Yang Zheng Hu; Organ shortage is a global issue.Data collected by the Global Observatory on Donation and Transplantation reveals that over 150,000 solid organ transplants are conducted globally each year,a 52%increase from 2010(http...; 关键词：globally GLOBAL SHORTAGE

The importance of public engagement in clinical xenotransplantation: 《Health Care Science》2024年第2期124-130,共7页Daniel J.Hurst David K.C.Cooper; Over the past several decades,significant scientific progress in xenotransplantation has brought the field to the threshold of clinical trials.In the past 3 years in the United States,experimental pig kidney and heart...; 关键词：clinical trials ETHICS public engagement VIEWPOINTS XENOTRANSPLANTATION

Clinical treatment procedure and experience of six gene-edited pigrhesus monkey heterotopic heart xenotransplantation: 《Chinese Medical Journal》2024年第8期997-999,共3页Bing Zhang Pengfei Ji Langang Peng Mengen Zhai Jiayou Tang Lin Zhao Yan Jin Baoling Xu Xiangni Lyu Linhe Lu Yenong Zhou Zhenxiao Jin Weixun Duan Xiuling Yang Wei Yi Jincheng Liu; Xijing Hospital Clinical New Technology Project(grant Nos.XJSZ03 and XJSM02); Heart transplantation is an effective treatment for endstage heart failure;however,problems such as the severe shortage of donor hearts,rejection,the toxic effects of immunosuppressants,and serious postoperative compl...; 关键词：DONOR treatment SHORTAGE

Multiple gene modifications of pigs for overcoming obstacles of xenotransplantation被引量：1: 《National Science Open》2023年第5期96-112,共17页Han Wu Meng Lian Liangxue Lai; supported by the National Key Research and Development Program of China(2022YFA1105404,2021YFF0702601 and 2021YFA0805300);the Research Unit of Generation of Large Animal Disease Models,Chinese Academy of Medical Sciences(2019I2M-5-025);the Science and Technology Program of Guangzhou(202201010409);the Key Research&Development Program of Hainan Province(ZDYF2021SHFZ052);the Major Science and Technology Project of Hainan Province(ZDKJ2021030);the 2020 Research Program of Sanya Yazhou Bay Science and Technology City(202002011); Xenotransplantation,involving animal organ transplantation into humans to address the human organ shortage,has been studied since the 17th century.Early attempts to obtain organs from animals such as goats,dogs,and no...; 关键词：XENOTRANSPLANTATION PIG immune rejection genetic modification

A bioartificial transgenic porcine whole liver expressing human proteins alleviates acute liver failure in pigs: 《Hepatobiliary & Pancreatic Diseases International》2023年第3期270-281,共12页Wei-Song Xue Hao-Jie Zhang Jing-Jing Ke Yu Fu Qing Peng Li Li Yi Gao Ke-Bo Zhong; supported by grants from the National Key R&D Program of China(2018YFC1106400 and 2018YFA0108200);the National Natural Science Foundation of China(31972926);the Natural Science Foundation of Guangdong Province(2014A030312013 and 2018A030313128);Guangdong Key Research and Development Plan(2019B020234003);Science and Technology Program of Guangzhou(201803010086);Guangdong Basic and Applied Basic Research Foundation(2020A1515111111)。; Background:Preventing heterologous protein influx in patients is important when using xenogeneic bioartificial livers(BALs)to treat liver failure.The development of transgenic porcine livers synthesizing human protein...; 关键词：Acute liver failure Transgenic pig Bioartificial liver XENOTRANSPLANTATION

Pig-to-Human xenotransplantation:Moving toward organ customization被引量：1: 《Precision Clinical Medicine》2023年第2期119-120,共2页Mengyu Gao Jie Zhang Rui Wang Guang Yang Ji Bao; supported by the National Natural Science Foundation of China(Grants No.82070640 and 81770618);the Fulltime Postdoctoral Research and Development Fund of West China Hospital,Sichuan University(Grant No.2023HXBH039).; Dear Editor,Xenotransplantation is a potentially effective way to address the shortage of organ donors.The improvements in gene editing technology have accelerated a number of a breakthrough in genetically modifying p...; 关键词：BREAKTHROUGH kidney HUMAN

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