Neuropeptide Y (NPY) is a ubiquitous endocrine neuropeptide found in vertebrate and invertebrate. In our present work, two NPY-like exocrine eouopeptides (designated as cono-NPYs) were first identified in the veno...
AIM: To define the ion channel target of SO-3, a new O-super-family conopeptide derived from Conus striatus. METHODS: Pharmacologically isolated whole-cell currents were recorded by patch-clamp technique in cultured h...
Conotoxins are short peptide-toxins with specific targets and large diversity. They are usetul in analgesia, neuroprotection, detection of some kinds of deseases, and receptor and ion channel study. in order to explor...
Project supported by the National 863 Hi-Tech project (Grant No. 819-06-04).
Conotoxins are small peptides in the venoms of Conus genus with various physiological activities targeting ion channels and receptors in the neuromuscular system. Applying a modified 3’-RACE (Rapid Amplification of c...