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作品数:127被引量:204H指数:7
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相关领域:医药卫生更多>>
相关作者:李亚平沈祖铭张贤英裴元英周建军更多>>
相关机构:复旦大学中国科学院上海生命科学研究院吉林正业生物制品股份有限公司江苏先声药业有限公司更多>>
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A third dose of inactivated vaccine augments the potency, breadth, and duration of anamnestic responses against SARS-CoV-2被引量:1
《Protein & Cell》2024年第12期930-937,共8页Zijing Jia Kang Wang Minxiang Xie Jiajing Wu Yaling Hu Yunjiao Zhou Ayijiang Yisimayi Wangjun Fu Lei Wang Pan Liu Kaiyue Fan Ruihong Chen Lin Wang Jing Li Yao Wang Xiaoqin Ge Qianqian Zhang Jianbo Wu Nan Wang Wei Wu Yidan Gao Jingyun Miao Yinan Jiang Lili Qin Ling Zhu Weijin Huang Yanjun Zhang Huan Zhang Baisheng Li Qiang Gao Xiaoliang Sunney Xie Youchun Wang Yunlong Cao Qiao Wang Xiangxi Wang 
supported by the Ministry of Science and Technology of China (CPL-1233 and SPRG22-003);CAS (YSBR-010);the National Science Foundation Grants (12034006,32325004 and T2394482);supported by National Science Fund for Distinguished Young Scholar (No. 32325004);the NSFS Innovative Research Group (No. 81921005)
Dear Editor,The ongoing coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has lasted for more than four years,resulting in an unprecedented global public h...
关键词:acute RESPIRATORY 
Analysing the Diagnostic Potency of Oral Glucose Tolerance Test at 20 Weeks of Gestation in High-Risk Pregnancies
《Open Journal of Obstetrics and Gynecology》2024年第12期1873-1895,共23页Madugalle Edirisinghe Mudiyanselage Yasassri Devinda Bandara Madugalle Rathnayake Mudiyanselage Chathura Rathnayake Tharunya Rajayohan Dhanushka Srikantha Kotigala Susil Anura Ruwanpathirana 
Background: Gestational Diabetes Mellitus (GDM) poses significant risks to both mothers and fetuses, with an escalating global prevalence. This study addresses the critical need for timely GDM detection in high-risk p...
关键词:Gestational Diabetes Mellitus (GDM) High-Risk Pregnancies Early Diagnosis of GDM GDM at 20 Weeks Oral Glucose Tolerance Test (OGTT) 
Open label,interventional,single arm multicentric clinical study to analyze the potency of VELNEZ nasal pack,post-nasal surgery
《World Journal of Otorhinolaryngology-Head and Neck Surgery》2024年第3期180-186,共7页Shama Bellad Nagula Parusharam Vineeta Dhyani Pankaj Bablani Siddharth Pandey 
funded by Datt Mediproducts Pvt.Ltd.
Background:Nasal packs are central to nasal surgeries.Primarily,these packs function by controlling bleeding,modulating pain and reducing adhesions post-surgery.However,the major setback of the currently used conventi...
关键词:clinical trial registry fragmentable functional endoscopic sinus surgery visual analog scale 
Intranasal adenovirus-vectored Omicron vaccine induced nasal immunoglobulin A has superior neutralizing potency than serum antibodies
《Signal Transduction and Targeted Therapy》2024年第8期3507-3518,共12页Si Chen Zhengyuan Zhang Qian Wang Qi Yang Li Yin Lishan Ning Zhilong Chen Jielin Tang Weiqi Deng Ping He Hengchun Li Linjing Shi yjun Deng Zijian Liu Hemeng Bu Yaohui Zhu Wenming Liu Linbing Qu Ligiang Feng Xiaoli Xiong Baoqing Sun Nanshan Zhong Feng Li ingchao Li Xinwen Chen Ling Chen 
The study was supported by the National Natural Science Foundation(92269201);Youth Innovation Promotion Association of CAS(2022361);Grants from Guangzhou National Laboratory(GZNL2024A01012,GZNL2023A01009);State Key Laboratory of Respiratory Disease(SKLRD-Z-202106,SKLRD-Z-202328);Science and Technology Projects in Guangzhou(SL2022A04J00604).
The upper respiratory tract is the initial site of SARS-CoV-2 infection.Nasal spike-specific secretory immunoglobulin A(slgA)correlates with protection against Omicron breakthrough infection.We report that intranasal ...
关键词:NASAL ANTIBODIES neutral 
Ionic potency regulation of coagulation bath induced by saline solution to control over the pore structure of PBI membrane for highperformance lithium metal batteries
《Journal of Energy Chemistry》2024年第7期288-298,共11页Arshad Hussain Waseem Raza Andleeb Mehmood Sana Jalees Lihong Ao Yonggui Deng Aymeric Ramiere Xingke Cai Dongqing Liu 
supported by the funding from the Natural Science Foundation of China (22105129);the Guangdong Basic and Applied Basic Research Foundation (2022A1515011048,2022A1515010670);the Science and Technology Innovation Commission of Shenzhen (JCYJ20200109105618137,20200812112006001)
In this study,we have explored the use of water as a non-solvent for tuning the microstructure of poly-benzimidazole(PBI)membranes,which are potential separators for lithium metal batteries(LMBs).The traditional metho...
关键词:Lithium metal-based battery Salt-induced POLYBENZIMIDAZOLE Tunablemorphology lonic potency 
Injectable thermo-sensitive hydrogel enhances anti-tumor potency of engineered Lactococcus lactis by activating dendritic cells and effective memory T cells
《Bioactive Materials》2024年第7期331-347,共17页Aoxing Chen Junmeng Zhu Rui Liu Yi Mei Lin Li Yue Fan Yaohua Ke Baorui Liu Qin Liu 
supported by the National Natural Science Foundation of China (82272811 and 81930080);the Fund for Distinguished Young Scholars of Jiangsu Province (BK20230001).
Engineered bacteria have shown great potential in cancer immunotherapy by dynamically releasing therapeutic payloads and inducing sustained antitumor immune response with the crosstalk of immune cells.In previous stud...
关键词:Cancer immunotherapy Engineered bacteria Thermos-sensitive hydrogel Localized drug delivery Artificial lymph node 
Ptip safeguards the epigenetic control of skeletal stem cell quiescence and potency in skeletogenesis被引量:1
《Science Bulletin》2024年第13期2099-2113,共15页Jianfei Liang Jing Wang Bingdong Sui Yibo Tong Jihua Chai Qin Zhou Chenxi Zheng Hao Wang Liang Kong Haojian Zhang Yi Bai 
supported by the National Key Research and Development Program of China(2022YFA0103200);the National Natural Science Foundation of China(82325003,82230007,82200188,82270956 and 82171568);the National Defense Biotechnology Outstanding Young Talents Fund(01-SWKJYCJJ24);Shaanxi Province Innovation Capability Support Program Scientific and Technological Innovation Team(2023-CX-TD-69).
Stem cells remain in a quiescent state for long-term maintenance and preservation of potency;this process requires fine-tuning regulatory mechanisms.In this study,we identified the epigenetic landscape along the devel...
关键词:Skeletal stem cells Bone development Epigenetics Ptip GLYCOLYSIS 
Discovering Tax Potency in Social Media Analytics:Indonesian Case Studies
《Belt and Road Initiative Tax Journal》2024年第1期20-25,共6页Iwan Djuniardi 
Social media influencers are one of the tax targets that have the potential to increase tax revenue significantly.There are many challenges that Indonesia's tax authority must face in collecting taxes from influencers...
关键词:Tax potential Social media Data Crawlers Computer Vision Graph Analytics 
Enhanced potency of an IgM-like nanobody targeting conserved epitope in SARS-CoV-2 spike N-terminal domain
《Signal Transduction and Targeted Therapy》2024年第6期2726-2737,共12页Bo Liu Honghui Liu Pu Han Xiaoyun Wang Chunmei Wang Xinxin Yan Wenwen Lei Ke Xu Jianjie Zhou Jianxun Qi Ruiwen Fan Guizhen Wu Wen-xia Tian George F.Gao Qihui Wang 
supported by the National Key R&D Program of China(2022YFC2303403);the National Science Fund for Distinguished Young Scholars(82225021);supported by the Young Scientists in Basic Research(YSBR-010).
Almost all the neutralizing antibodies targeting the receptor-binding domain(RBD)of spike(S)protein show weakened or lost efficacy against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)emerged or emerging...
关键词:doses prevention CONSERVED 
Harnessing the potency of scorpion venom-derived proteins:applications in cancer therapy
《Bioresources and Bioprocessing》2024年第1期1221-1243,共23页Jihad El-Qassas Mahmoud Abd El-Atti Nagwa El-Badri 
Open access funding provided by The Science,Technology&Innovation Funding Authority(STDF)in cooperation with The Egyptian Knowledge Bank(EKB).
Despite breakthroughs in the development of cancer diagnosis and therapy,most current therapeutic approaches lack precise specificity and sensitivity,resulting in damage to healthy cells.Selective delivery of anti-can...
关键词:SV-derived peptides Anticancer agents Cancer therapy Drug development Drug discovery Peptide therapeutics 
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