Β-ADRENOCEPTOR

作品数:22被引量:69H指数:4
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相关领域:医药卫生更多>>
相关作者:王立荣陈育智薛全福林友华赵琪平更多>>
相关机构:中国医学科学院北京协和医学院首都儿科研究所中日友好医院山东医科大学更多>>
相关期刊:《Science China(Life Sciences)》《Chinese Journal of Integrative Medicine》《Acta Pharmacologica Sinica》《Journal of Biomedical Research》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金更多>>
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Tale of two kinases:Protein kinase A and Ca^(2+)/calmodulin-dependent protein kinase Ⅱ in pre-diabetic cardiomyopathy被引量:1
《World Journal of Diabetes》2021年第10期1704-1718,共15页Pamela Gaitán-González Rommel Sánchez-Hernández José-Antonio Arias-Montaño Angélica Rueda 
Supported by SEP-Cinvestav Project,No.FIDSC 2018/2;and SEP-Conacyt Ciencia Básica 2017-2018,No.A1-S-9082(to Rueda A).
Metabolic syndrome is a pre-diabetic state characterized by several biochemical and physiological alterations,including insulin resistance,visceral fat accumulation,and dyslipidemias,which increase the risk for develo...
关键词:Ca^(2+)/calmodulin-dependent protein kinase II Protein kinase A Metabolic syndrome PRE-DIABETES Pre-diabetic cardiomyopathy β-Adrenoceptors 
β_2-adrenoceptor in obstructive airway diseases:Agonism, antagonism or both?被引量:1
《World Journal of Respirology》2015年第3期199-206,共8页Daniel WS Tan Jyi Lin Wong Siew Teck Tie John A Abisheganaden Albert YH Lim WS Fred Wong 
Supported by NMRC/CBRG/0027/2012 from the National Medical Research Council of Singapore(in part);by NUHS Seed Fund R-184-000-238-112
Obstructive airway disease is a complex disease entity including several maladies characterized by bronchoconstriction and abnormal airway inflammation. Reversing bronchoconstriction leads to symptomatic relief and im...
关键词:β-adrenoceptors β2-agonist Β-BLOCKER Inverse agonist Heart failure Β-ARRESTIN 
Parallel effects of β-adrenoceptor blockade on cardiac function and fatty acid oxidation in the diabetic heart: Confronting the maze被引量:8
《World Journal of Cardiology》2011年第9期281-302,共22页Vijay Sharma John H McNeill 
Supported by The Canadian Institutes of Health Research and the Heart and Stroke Foundation of Canada
Diabetic cardiomyopathy is a disease process in which diabetes produces a direct and continuous myocardial insult even in the absence of ischemic, hypertensive or valvular disease. The β-blocking agents bisoprolol, c...
关键词:Diabetes Heart failure Β-BLOCKERS CARDIAC metabolism FATTY acid oxidation 
Distinct actions of intermittent and sustained β-adrenoceptor stimulation on cardiac remodeling被引量:16
《Science China(Life Sciences)》2011年第6期493-501,共9页MA XiaoWei1,3,SONG Yao1,3,CHEN Chao1,3,FU YongNan1,3,SHEN Qiang2,3,LI ZiJian1,3 & ZHANG YouYi1,3 1Institute of Vascular Medicine,Peking University Third Hospital,Beijing 100191,China 2Institute of Cardiovascular Science,Peking University,Beijing 100191,China 3Key Laboratory of Molecular Cardiovascular Sciences,Ministry of Education,Beijing 100191,China 
supported by theNational Basic Research Program of China (Grant No. 2011CB503903);the National Natural Science Foundation of China (Grant Nos.81030001 and 30971161);the International Cooperation and Exchange of the National Natural Science Foundation of China (Grant No.30910103902)
Heart disease is associated with increased sympathetic nerve activity and elevated levels of circulating catecholamines,resulting in chronic stimulation of the β-adrenergic receptors (β-AR) and consequent pathologic...
关键词:Β-ADRENOCEPTOR reactive oxygen species NADPH oxidase cardiac hypertrophy cardiac fibrosis 
HIF-1α links β-adrenoceptor agonists and pancreatic cancer cells under normoxic condition被引量:4
《Acta Pharmacologica Sinica》2010年第1期102-110,共9页Heng-tong HU Qing-yong MA Dong ZHANG Su-gang SHEN Liang HAN Ya-dong MA Ruo-fei LI Ke-ping XIE 
Aim: To examine whether β-adrenoceptor (β-AR) agonists can induce hypoxia-inducible factor (HIF)-1α accumulation which then upregulate the expression of its target genes in pancreatic cancer cells at normoxia,...
关键词:β-adrenergic receptor epidermal growth factor receptor hypoxia-inducible factor-1α protein kinase A ERK1/2 Akt hypo-thalamic-pituitary-adrenal axis pancreatic cancer 
Differential Proteomic Analysis of Neonatal Cardiomyocytes in Response to β-Adrenergic Receptor Stimulation
《Chemical Research in Chinese Universities》2006年第3期319-323,共5页LI Zi-jian LIU Ning LIU Zhi-qiang LIU Shu-ying HAN Qi-de ZHANG You-yi 
SupportedbytheNationalKeyBasicResearchProgramofChina(No.G2000056906),theNationalNaturalScienceFoundationofChina(Nos.30400552and20273067)andtheResearchFundfortheDoctoralProgramofHigherEducation(No.20030001014).
β-Adrenoceptors(β-ARs) play a critical role in regulating cardiac functions under both physiological and pathological conditions. To further explore the mechanisms through which β-ARs perform its actions, proteom...
关键词:PROTEOME Two-dimensional electrophoresis(2-DE) MALDI-MS Β-ADRENOCEPTOR CARDIOMYOCYTE 
Effect of Electroacupuncture on Reperfusion Ventricular Arrhythmia in Rat
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第3期269-271,277,共4页曾青 李熳 欧阳兴飚 农艺 刘晓春 施静 关新民 
ProjectsupportedbythegrantofMajorResearchPlanofNationalNatureScienceFoundationofP.R.China(90209009).
Protective effect and mechanism of electroacupuncture (EA) on acute reperfusion ventricular arrhthmia was investigated. Ventricular arrhythmia was induced by occlusion of the proximal left anterior descend (LAD) b...
关键词:acute myocardial ischemia ventricular arrhythmia ELECTROACUPUNCTURE β-adrenoceptors M-cholinergic receptor 
CARDIAC RISK STRATIFICATION IN PATIENTS WITH CONGESTIVE HEART FAILURE:A CATECHOLAMINES-β-ADRENOCEPTOR-cAMP PATHWAY
《Chinese Medical Sciences Journal》2005年第2期93-98,共6页Ying-xinPeng JiangShan Su-junZhang Chun-liRong Jun-pingLi NaWang HaoXue Shi-lingZheng MinWu 
Supported by a research foundation of Hebei Provincial Science and Technology Commitee (399413 ).
Objective To investigate the stratification risk of catecholamines-β-adrenoceptor (β-AR)-cAMP pathway for cardiogenic death events in patients with congestive heart failure (CHF). Methods A total of 83 identified CH...
关键词:heart failure CATECHOLAMINE Β-ADRENOCEPTOR cyclic adenosine monophosphate 
β-Adrenoceptors potentiate α_1-adrenoceptor-mediated inotropic response in rat left atria被引量:2
《Acta Pharmacologica Sinica》2004年第1期29-34,共6页Yong-zhen ZHANG, You-yi ZHANG, Ming-zhe CHEN, Qi-de HANInstitute of Vascular Medicine, Peking University Third Hospital Key Laboratory of Ministry of Education for Molecular Cardiovasology, Beijing 100083, China 
ProjectsupportedbytheNaturalScienceFoundationofChina(30171083)theMajorStateBasicResearchDevelopmentProgramofPeople'sRepublicofChina(G2000056906).
AIM: To investigate whether stimulation of β-adrenoceptor (AR) and its subtypes augment α1-AR-evoked positive inotropic response and inositol phosphate (InsP) accumulation in isolated rat left atria. METHODS: Inotro...
关键词:alpha-1 adrenergic receptors beta adrenergic receptors heart atrium cardiac inotropism inositol phosphates adrenergic receptor antagonists adrenergic agonists 
Effects of thyroxine on cardiac function and lymphocyte β-adrenoceptors in patients with chronic congestive heart failure被引量:13
《Chinese Medical Journal》2003年第11期1697-1700,共4页卢新政 黄峻 张晓文 李新华 王赤京 张佩生 陈永生 
the Zhengzhou Railway Bureau Science Fund, China (99w33).
Objective To explore the effects of thyroid hormone (TH) on cardiac function and peripheral lymphocyte β-adrenoceptors (β-ARs) of patients with chronic congestive heart failure (CHF).Methods Twenty-eight patients wi...
关键词:thyroid hormone ·congestive heart failure cardiac function beta-adrenergic receptor 
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