云南高校图书馆联盟文献共享服务平台- CASCADE

CASCADE: 作品数：779被引量：1389H指数：14; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：王万龙刘达新董玉德杨华王红星更多>>; 相关机构：中国科学院浙江理工大学广东工业大学清华大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家高技术研究发展计划更多>>

Three-step synthesis of flavanostilbenes with a 2-cyclohepten-1-one core by Cu-mediated[5+2]cycloaddition/decarboxylation cascade: 《Chinese Chemical Letters》2025年第2期350-355,共6页Gangsheng Li Xiang Yuan Fu Liu Zhihua Liu Xujie Wang Yuanyuan Liu Yanmin Chen Tingting Wang Yanan Yang Peicheng Zhang; financial surpport from the CAMS Innovation Fund for Medical Sciences(CIFMS,No.2021-I2M-1-028);supported by Biomedical High Performance Computing Platform,Chinese Academy of Medical Sciences。; The first synthesis of flavanostilbenes with a 2-cyclohepten-1-one core was carried out by applying an effective strategy in three steps from abundant polymerized flavanol resources.A key regio-and stereoselective Cu-...; 关键词：[5+2]Cycloaddition Biomimetic synthesis Copper Natural products SUBSTRATE

Fe(Ⅲ)-juglone nanoscale coordination polymers for cascade chemodynamic therapy through synergistic ferroptosis and apoptosis strategy: 《Chinese Chemical Letters》2024年第11期413-418,共6页Zhendong Liu Sainan Liu Bin Liu Qi Meng Meng Yuan Chunzheng Yang Yulong Bian Ping'an Ma Jun Lin; financially supported by the National Key Research and Development Program of China(No.2022YFB3503700);the National Natural Science Foundation of China(NSFC,Nos.51929201,52102354,and 52202353);the projects for science and technology development plan of Jilin province(Nos.20220101070JC,20210402046GH,and 20220508089RC)。; Chemodynamic therapy(CDT)relying on the transformation of endogenous hydrogen peroxide(H_(2)O_(2))into cytotoxic hydroxyl radicals(·OH)based on the catalysis of Fenton/Fenton-type reactions exhibits great potentialit...; 关键词：Nanoscale coordination polymers JUGLONE Tumor microenvironment Enhanced chemodynamic therapy Ferroptosis

Continuous-flow synthesis of polysubstituted γ-butyrolactones via enzymatic cascade catalysis被引量：1: 《Chinese Chemical Letters》2024年第4期404-408,共5页Liliang Chu Xiaoyan Zhang Jianing Li Xuelei Deng Miao Wu Ya Cheng Weiping Zhu Xuhong Qian Yunpeng Bai; financially sponsored by the National Key Research and Development Program of China (No.2021YFC2102804);the National Natural Science Foundation of China(No.22078096)。; Polysubstituted chiral γ-butyrolactones are the core structural units of many natural products and high value-added flavors and fragrances used in the food and cosmetic industry. Current enzymatic cascade synthesis o...; 关键词：Enzyme catalysis Cascade catalysis Directed evolution CONTINUOUS-FLOW γ-Butyrolactones

Toehold-mediated strand displacement reaction-propelled cascade DNAzyme amplifier for microRNA let-7a detection被引量：1: 《Chinese Chemical Letters》2023年第6期211-214,共4页Na Wang Yongjian Jiang Kunhan Nie Di Li Hui Liu Jian Wang Chengzhi Huang Chunmei Li; financially supported by the National Natural Science Foundation of China(NSFC,Nos.22074124 and 22134005);the fund of Fundamental Research Funds for the Central Universities(No.XDJK2020TY001);Chongqing Talents Program for Outstanding Scientists(No.cstc2021ycjh-bgzxm0178);the Chongqing Graduate Student Scientific Research Innovation Project(No.CYB21119)。; DNAzyme amplifiers have been extensively explored as a useful sensing platform,but single DNAzyme amplifier is limited in biosensing applications by its low sensitivity.Herein,a cascade DNAzyme amplifier was designed ...; 关键词：DNAzyme amplifier Toehold-mediated strand displacement reaction Signal amplification let-7a Cancer marker

Engineering trienzyme cascade-triggered fluorescent immunosensor platform by sequentially integrating alkaline phosphatase, tyrosinase and horseradish peroxidase: 《Chinese Chemical Letters》2023年第4期444-448,共5页Yujie Sun Lei Wen Huili Ma Wenlin Ma Zhenqian Fu Yinhui Li Chengwu Zhang Lin Li Jinhua Liu; the National Natural Science Foundation of China (Nos. 22174065, 21974119);the Science and Technology Planning Project of Hunan Province (No. 2020RC_(3)046);Hunan Provincial Natural Science Foundation of China (No.2019JJ30020)。; Mulit-enzyme cascades are a major type of chemical transformations and play a crucial role in biological signal transduction and metabolism. Herein, a trienzyme cascade-triggered fluorescent immunosensor platform was ...; 关键词：Enzyme cascade Alkaline phosphatase TYROSINASE Horseradish peroxidase Cardiac troponin I

External electrolyte-free electrochemical one-pot cascade synthesis of 4-thiocyanato-1H-pyrazoles: 《Chinese Chemical Letters》2023年第2期206-209,共4页Wei-Bao He Sai-Jie Zhao Jing-Yang Chen Jun Jiang Xiang Chen Xinhua Xu Wei-Min He; financial support from the National Natural Science Foundation of China (No. 21902014);Hunan Provincial Natural Science Foundation of China (No. 2021JJ40429)。; A practical synthetic method for 4-thiocyanato-1H-pyrazoles through the electrochemical cascade reaction of hydrazines, 1,3-diones and NH4SCN under metal-, chemical oxidant-and external electrolyte-free conditions was...; 关键词：Green chemistry ELECTROCHEMISTRY Cascade reaction Multicomponent reaction THIOCYANATO

A microfluidic surface-enhanced Raman scattering(SERS) sensor for microRNA in extracellular vesicles with nucleic acid-tyramine cascade amplification被引量：2: 《Chinese Chemical Letters》2022年第4期2101-2104,共4页Yue Zhao Xiaoxing Fang Min Bai Jin Zhang Huahang Yu Feng Chen Yongxi Zhao; supported by the National Natural Science Foundation of China (Nos. 31671013, 22004096, 21874105and 21705124);the China Postdoctoral Science Foundation (Nos.2019M663658 and 2020T130096ZX);the Natural Science Basic Research Program of Shaanxi (Nos. 2020JQ-020, 2020JQ-021 and2018JC-001);the Fundamental Research Funds for the Central Universities (No. xzy012020034);“Young Talent Support Plan” of Xi’an Jiaotong University。; Exosomal micro RNA(mi RNA) is an ideal candidate of noninvasive biomarker for the early diagnosis of cancer. Sensitive and accurate sensing of abnormal exosomal mi RNA plays essential role for clinical promotion due t...; 关键词：Microfluidic chips Surface-enhanced Raman scattering(SERS) EXOSOME Tyramide signal amplification Nucleic acid amplification

High-performance cascade nanoreactor based on halloysite nanotubes-integrated enzyme-nanozyme microsystem: 《Chinese Chemical Letters》2022年第2期807-811,共5页Yan Liu Rui Lv Shiyong Sun Daoyong Tan Faqin Dong Yevgeny A.Golubev Xiaoqin Nie Olga B.Kotova Jin Liu Ke Wang; supported by the National Natural Science Foundation of China (NSFC,Nos.42061134018,42011530085 and 41877323);the Russian Science Foundation (RSF,No.21-4700019,Russia);the Sichuan Science and Technology Program (No.2019JDJQ0056,China)。; Various enzymatic reactions or enzymatic cascade reactions occur efficiently in biological microsystems due to space constraints or orderly transfer of intermediate products. Inspired by this, the horseradish peroxida...; 关键词：Halloysite nanotubes Fe-aminoclay Nanozyme Cascade nanoreactor Catalysis enhancement

Total syntheses of hyperaspidinols A and B enabled by a bioinspired diastereoselective cascade sequence: 《Chinese Chemical Letters》2022年第2期885-889,共5页Anquan Zheng Tingting Zhou Sasa Wang Wenge Zhang Xiuxiang Lu Huiyu Chen Haibo Tan; supported financially by the National Natural Science Foundation of China (Nos.81773602,21901049 and 21801032);Natural Science Foundation of Guangdong Province (No.2019A1515011694);Guangdong Special Support Program (No.2017TQ04R599);Youth Innovation Promotion Association of CAS (No.2020342);Guangxi Natural Science Foundation (Nos.2018GXNSFBA050015 and AD19245004)。; A bioinspired acid-triggered hemiacetalization/dehydration/[3 + 3]-type cycloaddition cascade process was disclosed, diastereoselectively furnishing furo[2,3-b]chromene skeleton under mild conditions. The viability of...; 关键词：Total synthesis Bioinspried DIASTEREOSELECTIVE Cascade reaction Hyperaspidinol

Molecular recognition triggered aptazyme cascade for ultrasensitive detection of exosomes in clinical serum samples: 《Chinese Chemical Letters》2021年第5期1827-1830,共4页Kemei Jiang Yanan Wu Juan Chen Mingqing Shi Hong-Min Meng Zhaohui Li; This work was supported by National Natural Science Founda-tion of China(Nos.21605038 and 21974125);China Postdoctoral Science Foundation(No.2019T120623).; Exosomes have attracted widespread interest due to their inherent advantages in tumor diagnosis and treatment monitoring.However,it is still a big challenge for highly sensitive and specific detection of exosome in re...; 关键词：Aptazyme EXOSOMES Fluorescence probe Signal amplification Clinical serum samples

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