BACKGROUNDParagonimiasis is a typical food-borne zoonotic disease. Hosts acquire Paragonimusinfection through the ingestion of raw or undercooked crayfish and crab.The clinical manifestations of the disease are varied...
Background Over the past two decades,preventive chemotherapy(PC)with praziquantel(PZQ)is the major strategy for controlling schistosomiasis in Senegal.The objective of this analysis was to update the endemicity of sch...
The authors acknowledge the National Natural Science Foundation of China(No.22278443);CAMS Innovation Fund for Medical Sciences(No.2022-I2M-1-015);the Key R&D Program of Shan Dong Province(No.2019JZZY020909);the Xinjiang Uygur Autonomous Region Innovation Environment Construction Special Fund and Technology Innovation Base Construction Key Laboratory Open Project(No.2022D04016)for the financial support.
Co-crystal formation can improve the physicochemical properties of a compound,thus enhancing its druggability.Therefore,artificial intelligence-based co-crystal virtual screening in the early stage of drug development...
Schistosomiasis(bilharziasis)is a major neglected tropical disease.It is endemic in many tropical and subtropical communities.Schistosomal polyps(S.polyps)are not uncommon presentation of this infection.Although the c...
The objective of this small pilot study was to test the efficacy and potential development for the use of Praziquantel IM Cestodicide in South African goats. Two farms were identified as infected with the Cestode Moni...
Background In certain settings,the prevalence and severity of schistosoma infection do not lessen despite repeated rounds of preventative chemotherapy;these areas are known as hotspots.This study aimed to investigate ...
The aim of the study was to assess the effect of praziquantel (PZQ) treatment on hematuria, proteinuria and the status of eGFR following treatment in school children infected with S. mansoni. A cohort study among 6 - ...
Background:Celosia laxa (Amaranthaceae) is mainly a west African plant species used in Traditional Medicine as an anthelmintic, anticancer, antibacterial and a...
Background:To monitor the prevalenee of schistosomiasis in school-aged children(SAC),the National Bilharzia Control Program(PNLB)was set up by the Senegalese authorities;however,geographically isolated Bedik ethnic gr...
School-aged children(SAC)have a considerable burden of intestinal schistosomiasis in Madagascar yet its burden in pre-school aged children(PSAC)is currently overlooked.To assess the at-risk status of PSAC,we undertook...