WILD-TYPE

作品数：121被引量：282H指数：8
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相关领域：医药卫生生物学更多>>
相关作者：牟珍珍姚庆宇王丽杰袁茵李静云更多>>
相关机构：北京大学第四军医大学西京医院四川省肿瘤医院中国医学科学院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金天津市自然科学基金更多>>
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Kinetics of blue-green light-induced state transition and fluorescence quenching in the wild-type cyanobacterium Synechocystis PCC 6803 and apc D2 and apc F2 mutants
《Chinese Science Bulletin》2014年第34期4712-4719,共8页Wenfeng Zhao Jie Xie Jingquan Zhao 
supported by the Chinese Academy of Sciences(KJCX2-YW-W25)
State transition and blue-green light-induced fluorescence quenching are two short-term processes in cyanobacteria. The details of their kinetics and the relationship between these processes have not been elucidated.I...
关键词：荧光动力学 状态转换 野生型 光诱导 突变体 PCC 集胞藻 蓝绿色 
MDM2 antagonist Nutlin-3a protects wild-type p53 cancer cells from paclitaxel
《Chinese Science Bulletin》2012年第9期1007-1012,共6页SHEN HongChang DONG Wei GAO DongWei WANG GuangHui MA GuoYuan LIU Qi DU JiaJun 
supported by the National High-Tech Research and Development Program of China (2007AA021802);the Provincial Natural Science Foundation of Shandong (ZR2010HM067 and ZR2011HM077)
The p53 pathway has an important role in cell cycle arrest and apoptosis.Downregulated levels of p53 have been shown to increase resistance to the cytotoxic effects of chemotherapy or radiotherapy.MDM2(murine double m...
关键词：p53蛋白 MDM2 紫杉醇 癌细胞 野生型 拮抗剂 保护 A549细胞 
Metal ion-binding properties of wild-type and mutant D37K of ciliate Euplotes octocarinatus centrin
《Chinese Science Bulletin》2010年第27期3118-3122,共5页LIU Wen DUAN Lian ZHAO YaQin LIANG AiHua YANG BinSheng 
supported by the National Natural Science Foundation of China(20771068,20901048);the Ph.D Programs Foundation of Ministry of Education of the People’s Republic of China(20091401110007);the Natural Science Foundation of Shanxi Province(2007011024)
Ciliate Euplotes octocarinatus centrin (EoCen) is an EF-hand calcium-binding protein closely related to the prototypical calcium sensor protein calmodulin.The first amino acid of the Ca2+-binding loops found in the EF...
关键词：CENTRIN 金属离子 突变型 纤毛虫 结合特性 游仆虫 野生型 钙结合蛋白 
Comparative pluripotency analysis of mouse embryonic stem cells derived from wild-type and infertile hermaphrodite somatic cell nuclear transfer blastocysts
《Chinese Science Bulletin》2008年第23期3648-3655,共8页FAN Yong TONG Man ZHAO ChunLi DING ChenHui HAO Jie LV Zhuo DAI XiangPeng HAI Tang LI XueMei YAO RuQiang YU Yang LI ZanDong WANG Liu ALICE Jouneau ZHOU Qi 
the National Nature Science Foundation of China (Grant Nos. 30525040 and 30670229)
Therapeutic cloning, whereby embryonic stem cells (ESCs) are derived from patient-specific cloned blastocysts via somatic cell nuclear transfer (SCNT), holds great promise for treating many human diseases using regene...
关键词：体细胞核转移 胚胎干细胞 生物疗法 雌雄同体 
Three-dimensional structure of the wild-type RHDV被引量：3
《Chinese Science Bulletin》2001年第12期1005-1009,共5页ZHENG Dong XUE Tao CHEN Donghua ZHENG Ming Z.H.ZHOU XU Wei 
This work was supported by the National Natural Science Foundation of China (Grant Nos. 69501008 and 19634020); Research in Houston has been supported by NIH (AI 46420) and the Welch Foundation (AU-1492).
The three-dimensional (3D) structure of the wild-type rabbit hemorrhagic disease virus (RHDV) has been determined to a resolution of 3.2 nm by electron cryo-microscopy and computer image reconstruction techniques. The...
关键词：ELECTRON CRYOMICROSCOPY THREE-DIMENSIONAL reconstruction RHDV calicivirus. 
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