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作品数:121被引量:282H指数:8
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相关领域:医药卫生生物学更多>>
相关作者:牟珍珍姚庆宇王丽杰袁茵李静云更多>>
相关机构:北京大学第四军医大学西京医院四川省肿瘤医院中国医学科学院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划广东省自然科学基金天津市自然科学基金更多>>
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  • 期刊=World Journal of Gastrointestinal Oncologyx
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Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors
《World Journal of Gastrointestinal Oncology》2025年第3期13-18,共6页Yuan Liu Xiao-Feng Li 
National Natural Science Foundation of China,No.82370569;Basic and Applied Basic Research Foundation of Guangdong Province,No.2022A1515012647;the Key Program for Science and Technology Projects of Social Development in Zhuhai,No.2220004000249(to Li XF).
This editorial discusses Wang et al's article on familial gastrointestinal stromal tumors(GISTs).We read with great interest this article concerning the diagnosis,treatment,and post-treatment management of patients wi...
关键词:Gastrointestinal stromal tumors KIT mutation Platelet-derived growth factor receptor alpha mutation Wild-type gastrointestinal stromal tumor Tyrosine kinase inhibitors Familial gastrointestinal stromal tumor syndromes Molecular characteristics Targeted therapy 
Two different mutational types of familial gastrointestinal stromal tumors:Two case reports被引量:1
《World Journal of Gastrointestinal Oncology》2024年第9期4028-4036,共9页Xiao-Ke Wang Lu-Fan Shen Xin Yang He Su Tao Wu Peng-Xian Tao Hong-Ying Lv Tong-Han Yao Lin Yi Yuan-Hui Gu 
National Natural Science Foundation of China,No.82160842;Clinical Research Project of Research Fund of Gansu Provincial Hospital,No.23GSSYD-17;General Program of the Joint Scientific Research Fund,No.23JRRA1521.
BACKGROUND Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal(GI)tract,and cases of GISTs tend to be of the disseminated type,with a global incidence of 10 to 15 cases...
关键词:Gastrointestinal stromal tumor Familial gastrointestinal stromal tumor Wild-type gastrointestinal stromal tumors PDGFRA IMATINIB Treatment Case report 
Emerging role of liquid biopsy in rat sarcoma virus mutated metastatic colorectal cancer:A case report被引量:1
《World Journal of Gastrointestinal Oncology》2024年第1期234-243,共10页João Gramaça Isabel Gomes Fernandes Carolina Trabulo Joana Gonçalves Rita Gameiro dos Santos Adriano Baptista Idília Pina 
BACKGROUND In patients with metastatic colorectal cancer(mCRC),the treatment options are limited and have been proved to be affected by rat sarcoma virus(RAS)mutational status.In RAS wild-type(wt)patients,the combinat...
关键词:Metastatic colorectal cancer Rat sarcoma virus mutational status Liquid biopsy Rat sarcoma virus wild-type Neo-rat sarcoma virus wild-type Anti-epidermal growth factor receptor therapy Case report 
Maspin subcellular expression in wild-type and mutant TP53 gastric cancers被引量:1
《World Journal of Gastrointestinal Oncology》2020年第7期741-755,共15页Simona Gurzu Ioan Jung Haruhiko Sugimura Raluca Ioana Stefan-van Staden Hidetaka Yamada Hiroko Natsume Yuji Iwashita Rita Szodorai Janos Szederjesi 
the Romanian National Authority for Scientific Research;No.20 PCCF/2018。
BACKGROUND Although the role of p53 in the evolution and prognosis of gastric cancer(GC)has been extensively examined,the exact mechanism of action is incompletely understood.In the last years,p53-target genes were su...
关键词:p53 TP53 gene MASPIN Gastric cancer Carcinoma 
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