云南高校图书馆联盟文献共享服务平台- PDGFRA

PDGFRA: 作品数：88被引量：193H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：钱静王新法张瑞何俊平王刚更多>>; 相关机构：华中科技大学中国医学科学院北京协和医学院复旦大学北京协和医院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金河南省基础与前沿技术研究计划项目天津市自然科学基金北京市科技计划项目更多>>

西藏地区PDGFRA和RB1共突变胃间质瘤1例临床病理学分析: 《西藏医药》2025年第2期193-193,共1页德吉卓嘎普布穷达嘎玛曲珍穆晶; 西藏自治区自然科学基金组团式援藏医学项目[XZ2023ZR-ZY32(Z)]。; 1病例资料患者男性,32岁,藏族人,发现腹腔巨大包块1月余入院。腹部CT显示胃大弯侧腔内外混合生长哑铃状肿物(图1)。病理检查:带部分胃的双结节肿物,小结节位于胃壁粘膜下,突向胃腔,大小5cm×4cm×4cm,切面灰白实性,质韧;大结节与小结节...; 关键词：共突变 PDGFRA 胃间质瘤临床病理学

Pdgfrα+stromal cells,a key regulator for tissue homeostasis and dysfunction in distinct organs: 《Genes & Diseases》2025年第2期181-201,共21页Xia Kang Kun Zhao Zhu Huang So-ichiro Fukada Xiao-wei Qi Hongming Miao; supported by grants from the National Natural Science Foundation of China (No.82173134 to H.M.);the Sichuan Science and Technology Program (China) (No.2023ZYD0061 to X.K.);the funding of Jinfeng Laboratory (Chongqing,China);China Postdoctoral Science Foundation (No.2020M673648 to X.K.);Chongqing Postdoctoral Science Special Foundation (China) (to X.K.);Chongqing Science and Technology Bureau (China) (No.CSTB2022TIADKPX0168 to X.Q.).; Pdgfra+stromal cells are a group of cells specifically expressing Pdgfra,which may be mentioned with distinct names in different tissues.Importantly,the findings from numerous studies suggest that these cells share ex...; 关键词：Fatty infiltration FIBROSIS Pdgfra^(+)stromal cell Tissue degeneration Tissue regeneration

伴恶性肿瘤的小胃肠间质瘤临床病理学特征: 《临床与实验病理学杂志》2025年第3期385-389,共5页曹然刘菊梅梁丽李鑫李东巴晓军张继新; 目的探讨伴恶性肿瘤的小胃肠间质瘤(small gastrointestinal stromal tumors,sGIST)的临床病理学特征。方法收集92例sGIST临床资料,采用免疫组化检测CD117、DOG1、CD34、Ki67、SMA和S-100的表达,应用一代测序法检测C-KIT、PAGFRA的突变...; 关键词：胃肠道间质瘤恶性肿瘤基因突变 C-KIT PDGFRA

Exploration of the immunologic characteristics of KIT/PDGFRA wild-type gastrointestinal stromal tumor and potential application of neoantigen vaccination: 《Chinese Medical Journal》2024年第21期2627-2629,共3页Yishan Li Qin Wang Lin Li Shaohua Yuan Hui Chen Rutian Li Fangcen Liu; supported by the Natural Science Foundation of China(Nos.82203178,82272852,and 82103687);Jiangsu Provincial Key Research and Development Program(No.BE2020619);Natural Science Foundation of Jiangsu Province(No.BK20220191);Nanjing Medical Science and Technology Development Foundation(No.YKK22086).; To the Editor:Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal tract.GISTs mostly occur in the stomach or small intestine among patients around 40-60 years of age,an...; 关键词：gastrointestinal STOMACH INTESTINE

Two different mutational types of familial gastrointestinal stromal tumors:Two case reports被引量：1: 《World Journal of Gastrointestinal Oncology》2024年第9期4028-4036,共9页Xiao-Ke Wang Lu-Fan Shen Xin Yang He Su Tao Wu Peng-Xian Tao Hong-Ying Lv Tong-Han Yao Lin Yi Yuan-Hui Gu; National Natural Science Foundation of China,No.82160842;Clinical Research Project of Research Fund of Gansu Provincial Hospital,No.23GSSYD-17;General Program of the Joint Scientific Research Fund,No.23JRRA1521.; BACKGROUND Gastrointestinal stromal tumors(GISTs)are the most common mesenchymal tumors of the gastrointestinal(GI)tract,and cases of GISTs tend to be of the disseminated type,with a global incidence of 10 to 15 cases...; 关键词：Gastrointestinal stromal tumor Familial gastrointestinal stromal tumor Wild-type gastrointestinal stromal tumors PDGFRA IMATINIB Treatment Case report

FIP1L1/PDGFRa基因阳性嗜酸性粒细胞增多性心内膜炎一例: 《临床内科杂志》2024年第8期557-558,共2页乌云其达木改白杨周强; 患者,男,21岁,因“二尖瓣机械瓣置换术后1个半月,胸闷、胸痛3日”于2020年11月4日收入我科。患者1个半月前因胸闷、胸痛来我院就诊,门诊以“二尖瓣关闭不全、感染性心内膜炎、心力衰竭”收入我院心脏大血管外科,查WBC计数及嗜酸性粒细...; 关键词：嗜酸细胞增多综合征二尖瓣关闭不全心内膜炎伊马替尼

Effect and safety of ripretinib in the treatment of advanced gastrointestinal stromal tumor:A systematic review and metaanalysis: 《World Journal of Clinical Oncology》2024年第8期1092-1101,共10页Ji Li Hao Zhang Xiao-Dong Chen; BACKGROUND Imatinib(IMA)has received approval as the primary treatment for gastrointestinal stromal tumors(GIST).Nonetheless,approximately half of the patients with advanced GIST show disease advancement following IMA...; 关键词：Gastrointestinal stromal tumor Ripretinib PDGFRA KIT META-ANALYSIS

原发性高嗜酸粒细胞增多症2例报道: 《现代医药卫生》2024年第9期1617-1620,共4页朱远琴吴金燕李招权; 外周血嗜酸粒细胞绝对计数大于0.5×10^(9) L^(-1)称为嗜酸粒细胞增多症,外周血嗜酸粒细胞持续大于或等于1.5×10^(9) L^(-1)称为高嗜酸粒细胞增多症(HE),并常伴有组织器官损伤,依据引起嗜酸粒细胞增多的原因HE可分为继发性、原发性、...; 关键词：原发性高嗜酸粒细胞增多症髓系肿瘤伴嗜酸粒细胞增多 PDGFRA重排慢性嗜酸粒细胞白血病病例报告

Avapritinib治疗血小板源性生长因子受体α外显子18突变的晚期胃肠间质瘤的研究进展: 《临床医学进展》2024年第3期402-408,共7页刘昆李洋; 胃肠间质瘤(GIST)是一类起源于胃肠道间叶组织的肿瘤,可根据编码受体酪氨酸激酶蛋白(KIT)和血小板源性生长因子受体α (PDGFRA)突变进行分子分类。酪氨酸激酶抑制剂(tyrosine kinase inhibitor, TKI)是胃肠间质瘤全身治疗的基础药物,显...; 关键词：Avapritinib 胃肠间质瘤 PDGFRA突变 D842V突变研究进展

PDGFRA基因突变型胃肠间质瘤生物学行为再研究被引量：1: 《中华病理学杂志》2024年第1期46-51,共6页袁伟黄雯任磊梁怀予董思瑶都向阳徐晨方勇沈坤堂侯英勇; 上海市科学技术委员会科研计划项目(19MC1911000);复旦大学附属中山医院临床研究专项基金(2020ZSLC01)。; 目的:探讨血小板源生长因子α受体(PDGFRA)基因突变型胃肠间质瘤(gastrointestinal stromal tumor,GIST)的生物学行为谱系,比较复旦大学附属中山医院良恶性评估方法与改良版美国国立卫生研究院(NIH)危险度分级的临床应用效能。方法:收...; 关键词：胃肠道间质肿瘤受体血小板源生长因子α 预后

PDGFRA