supported by JSPS KAKENHI(No.21K06192 to S.Y.and 17H03584,18K19484,and 20H03519 to K.Y.);the Jikei University Research Fund(to K.Y.);the Takeda Science Foundation(to S.Y.);the Uehara Memorial Foundation(to S.Y.and K.Y.).
The dual-specificity tyrosine-regulated kinase (DYRK) family is evolutionarily conserved from invertebrate to mammals. DYRKs regulate cell proliferation, apoptosis, survival, and differentiation by modifying the prote...
the National Institutes of Health(R01DK090038,1R01DK099160);P30 center grant(P30DK90728).
Tubulin posttranslational modifications(PTMs)add*tubulin code*to generate functional diversities of microtubules.Several types of tubulin PTMs accumulate on axonemes and basal bodies of cilia,including acetylation,glu...