EMBRYOGENESIS

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The regulatory network and critical factors promoting programmed cell death during embryogenesis
《Journal of Integrative Plant Biology》2025年第1期55-70,共16页An Luo Ce Shi Pan Luo Zifu Zhao Meng-Xiang Sun 
financially supported by the National Natural Science Foundation of China(31700281,32000248,32130031);the Postdoctoral Science Foundation of China(BX20200256,2020M682466)。
Programmed cell death(PCD)is essential for animal and plant development.However,the knowledge of the mechanism regulating PCD in plants remains limited,largely due to technical limitations.Previously,we determined tha...
关键词：programmed cell death PROTEASE reactive oxygen species SUSPENSOR TRANSCRIPTOME 
Effects of gravity,microgravity or microgravity simulation on early mouse embryogenesis:A review of the first two space embryo studies
《Mechanobiology in Medicine》2024年第4期7-14,共8页Douglas M.Ruden Daniel A.Rappolee 
supported by an NIH ECHO grant to DMR,UG3 OD023285.
Many simulated micro-gravity(micro-G)experiments on earth suggest that micro-G conditions are not compatible with early mammalian embryo development.Recently,the first two“space embryo”studies have been published sh...
关键词：MICROGRAVITY CLINOSTAT International space station(ISS) EMBRYOGENESIS 
Dynamic RNA methylation modifications and their regulatory role in mammalian development and diseases
《Science China(Life Sciences)》2024年第10期2084-2104,共21页Wenlan Yang Yongliang Zhao Yungui Yang 
supported by the National Natural Science Foundation of China(32121001,32201213)。
Among over 170 different types of chemical modifications on RNA nucleobases identified so far,RNA methylation is the major type of epitranscriptomic modifications existing on almost all types of RNAs,and has been demo...
关键词：RNA methylation(m^(6)A m5C and m7G) detection techniques RNA metabolism GAMETOGENESIS EMBRYOGENESIS immune system development TUMORIGENESIS 
CShaperApp:Segmenting and analyzing cellular morphologies of the developing Caenorhabditis elegans embryo
《Quantitative Biology》2024年第3期329-334,共6页Jianfeng Cao Lihan Hu Guoye Guan Zelin Li Zhongying Zhao Chao Tang Hong Yan 
National Natural Science Foundation of China,Grant/Award Numbers:12090053,32088101;Hong Kong Innovation and Technology Fund,Grant/Award Numbers:GHP/176/21SZ,InnoHK Project CIMDA;Hong Kong Research Grants Council,Grant/Award Numbers:11204821,HKBU12101323,HKBU12101520,HKBU12101522,N_HKBU201/18。
Caenorhabditis elegans has been widely used as a model organism in developmental biology due to its invariant development.In this study,we developed a desktop software CShaperApp to segment fluorescence-labeled images...
关键词：C.elegans embryogenesis cellular morphology cellular segmentation deep learning desktop software 
Paired box proteins as diagnostic biomarkers for endocervical adenocarcinoma
《World Journal of Clinical Cases》2024年第26期5854-5858,共5页Jia-Hui Zhou Xiang-Ning Zhang 
In this editorial,we commented on the article by Akers et al published in the recent issue of the World Journal of Clinical Cases.We focused specifically on the role of the transcription factor paired box protein 8(PA...
关键词：Cervical adenocarcinoma Diagnostic biomarker Paired box protein 8 EMBRYOGENESIS Transcription factor 
Achieving single-cell-resolution lineage tracing in zebrafish by continuous barcoding mutations during embryogenesis
《Journal of Genetics and Genomics》2024年第9期947-956,共10页Zhan Liu Hui Zeng Huimin Xiang Shanjun Deng Xionglei He 
supported by the National Key R&D Program of China(2021YFA1302500 and 2021YFA1302501);the National Natural Science Foundation of China(32293190,32293191,31970570,and 32200492).
Unraveling the lineage relationships of all descendants from a zygote is fundamental to advancing our understanding of developmental and stem cell biology.However,existing cell barcoding technologies in zebrafish lack...
关键词：Lineage tracing Cellular barcoding Zebrafishcell phylogeny Fin regeneration Germcell lineage 
The Role of N^(6)-methyladenosine Modification in Gametogenesis and Embryogenesis:Impact on Fertility
《Genomics, Proteomics & Bioinformatics》2024年第4期31-46,共16页Yujie Wang Chen Yang Hanxiao Sun Hui Jiang Pin Zhang Yue Huang Zhenran Liu Yaru Yu Zuying Xu Huifen Xiang Chengqi Yi 
supported by the National Natural Science Foundation of China(Grant No.82071614 to Huifen Xiang and Grant No.82101783 to Zuying Xu);the National Key R&D Program of China(Grant No.2021YFC2700600);the Anhui Medical University School Fund(Grant No.2020xkj182)。
The most common epigenetic modification of messenger RNAs(mRNAs)is N^(6)-methyladenosine(m^(6)A),which is mainly located near the 30 untranslated region of mRNAs,near the stop codons,and within internal exons.The biol...
关键词：SPERMATOGENESIS OOGENESIS EPIGENETICS N^(6)-methyladenosine Reproduction 
Prenatal cadmium exposure impairs neural tube closure via inducing excessive apoptosis in neuroepithelium
《Journal of Environmental Sciences》2024年第4期572-584,共13页Shiyong Zhu Xuenan Li Xueyan Dai Jinlong Li 
supported by the National Natural Science Foundation of China(No.32172932);the Key Program of Natural Science Foundation of Heilongjiang Province of China(No.ZD2021C003);the China Agriculture Research System of MOF and MARA(No.CARS-35);the Distinguished Professor of Longjiang Scholars Support Project(No.T201908);the Heilongjiang Touyan Innovation Team Program。
Birth defects have become a public health concern.The hazardous environmental factors exposure to embryos could increase the risk of birth defects.Cadmium,a toxic environmental factor,can cross the placental barrier d...
关键词：Cadmium Neural tube closure Excessive apoptosis p53 EMBRYOGENESIS 
Alternative splicing of POUM2 regulates embryonic cuticular formation and tanning in Bombyx mori
《Insect Science》2023年第5期1267-1281,共15页Chunmei Tong Kang Zhang Zixia Rong Wanyu Mo Yuling Peng Sichun Zheng Qi-Li Feng Huimin Deng 
supported by grants from the National Natural Science Foundation of China(No.31872969,No.31930102).
Insect cuticle is an apical extracellular matrix produced by the epidermis,tracheal,hind-and foregut epithelia during embryogenesis and renewed during molting and metamorphosis.However,the underlying regulatory mechan...
关键词：alternative splicing cuticular formation EMBRYOGENESIS POUM2 TANNING 
A pattern recognition receptor C-type lectin TcCTL14 contributes to immune response and development in the red flour beetle, Tribolium castaneum
《Insect Science》2023年第5期1363-1377,共15页Yonglei Zhang Huayi Ai Yihan Wang Ping Zhang Liheng Du Jiatao Wang Suisui Wang Han Gao Bin Li 
supported by grants from the National Natural Science Foundation of China to Bin Li(Grant number:31872970 and 32170521).
Evidence is accumulating that pattern recognition receptor(PRR)C-type lectins(CTL)play essential roles in recognition of pathogens.TcCTL14(accession no.TC00871)contains the most domains among all CTL of Tribolium cast...
关键词：C-type lectins EMBRYOGENESIS FECUNDITY immune response metamorpho-sis Tribolium castaneum 
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