supported by grants from the National Natural Science Foundation of China for Dai (Grant No. 81472188) and Zheng (Grant No. 81702247);the Youth Development Project of TMMU for Zheng (Grant No. 2016XPY17)
Objective: Cancer vaccines that rely on tumor antigen-specific CD8^+ T cell responses, are promising anti-cancer adjuvant immunotherapies. This study investigated whether genetically attenuated Plasmodium sporozoite(G...
Investigation of the intimate relationship between the human malaria parasite Plasmodium falciparum and its Anopheles vector requires the reliable production and isolation of successive sexual stages of the parasite f...
Ionizing radiation has been successfully used to attenuate parasites for malaria vaccine development. To get a deeper insight in the immune response post injection of irradiated pre-erythrocytic stage of malaria paras...
supported by Natural Science Foundation of Jilin Province for Outstanding Young scientists Award,China(2002).
The CP15/60 gene encoding the CP15/60 surface protein of sporozoites in Cryptosporidiumparvum was obtained by PCR so as to research the nucleic vaccine against C.parvum. Theeukaryotic expressing vector pcDNA3-15/60 wa...
Objective To detect malaria DNA in mosquitoes.Methods A nested polymerase chain reaction (nested PCR) procedure which amplifies a 121 bp DNA of a SSUrRNA gene specific to Plasmodium vivax was used.Results In labora...
The effects of nitroquine on the sporogony of Plasmodium yoelii werestudied with electron microscope.The drug was given by feeding female mosqui-toes directly in the form of mixture with sucrose solution.Scanning elec...