COMPETENT

作品数：75被引量：117H指数：7
导出分析报告
相关领域：医药卫生更多>>
相关作者：李阳李晓理冷雪莲张琪吴孟超更多>>
相关机构：东北师范大学北京科技大学中国传媒大学四川外国语大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划北京市自然科学基金上海市青年科技启明星计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 基金=国家重点基础研究发展计划x
共 条 记 录，以下是1-5
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
A two-step lineage reprogramming strategy to generate functionally competent human hepatocytes from fibroblasts被引量：10
《Cell Research》2019年第9期696-710,共15页Bingqing Xie Da Sun Yuanyuan Du Jun Jia Shicheng Sun Jun Xu Yifang Liu Chengang Xiang Sitong Chen Huangfan Xie Qiming Wang Guangya Li Xuehui LYU Hui Shen Shiyu Li Min Wu Xiaonan Zhang Yue Pu Kuanhui Xiang Weifeng Lai Peng Du Zhenghong Yuan Cheng Li Yan Shi Shichun Lu Hongkui Deng 
We thank Prof. Tungtien Sun for the guidance of the written manuscript. This work was supported by National Key Research and Development Program of China (2017YFA0104003,2017YFA0103000,2018YFA0108102);National Natural Science Foundation of China(31730059,31521004,81670590);SLS-Qidong Innovation Fund(2016000663);National Basic Research Program of China(973 Program 2015CB964703).
Terminally differentiated cells can be generated by lineage reprogramming,which is,however,hindered by incomplete conversion with residual initial cell identity and partial functionality. Here, we demonstrate a new re...
关键词：hepatic progenitor-like cells (hHPLCs) primary human HEPATOCYTES (PHHs) FIBROBLASTS 
Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice被引量：7
《Cell Research》2014年第9期1050-1066,共17页Jizheng Chen Yang Zhao Chao Zhang Hairong Chen Jin Feng Xiumei Chi Yu Pan Jun Du Min Guo Huang Cao Honghe Chen Zilong Wang Rongjuan Pei Qian Wang Lei Pan Junqi Niu Xinwen Chen Hong Tang 
Acknowledgments We are grateful to Drs T Wakita （National Institute of Infec- tious Diseases, Japan） for pJFH-1 clone, F Chisari （The Scripps Research Institute） for Huh7.5.1 cell line, L Su （University of North Carolina） for cDNA clones of human CD81 and Occludin, and C Rice （The Rockefeller University） for NS5A antibody. We thank Drs Y Tian and S Meng for making a series of transgenic mice; C-X Wei for the genotyping of transgenic mice. We thank Drs L Su, Y-X Fu （The University of Chicago）, R Sun （University of California, Los Angeles） and P Hertzog （Monash University, Australia） for their critical reading and comments on the manuscript. This work was supported by grants from the National Basic Research Program of China （2009CB522506 and 2011CB946104 to HT, 2009CBl18903 to XC, and 2010CB530100 to LP）, the National Natural Science Foundation of China （31200135 to XC and 31030031 to HT）, Knowledge Innovation Program Projects of Chinese Academy of Science （2010-Biols-CAS-0201to HT, and KSCXI-YW-10 to XC and HT）.
The majority of hepatitis C virus （HCV） infection develops chronic infection, which causes steatosis, cirrhosis and hepatocellular carcinoma. However, understanding HCV chronicity and pathogenesis is hampered by its...
关键词：HCV animal model humanized mice immune-competent 
Derivation of Germline Competent Rat Embryonic Stem Cells from DA Rats被引量：3
《Journal of Genetics and Genomics》2012年第11期603-606,共4页Tianda Li Xiao-Yang Zhao Fei Teng Xin Li Minggui Jiang Wei Li Xuepeng Wang Jialiang Wang Lei Liu Zhonghua Liu Liu Wang Qi Zhou 
supported by the grants from the China National Basic Research Program(No.2012CB966501) to X.Z;the National High Technology R&D Program of China (No.2011AA020108) to Q.Z.;the "Strategic Priority Research Program" of the Chinese Academy of Sciences(No. XDA01030101)
The laboratory rat was one of the earliest mammalian species for scientific research and used as animal disease models in physiology, toxicology, behavior, immunology, and tumor-biology for over 150 years （Jacob, 199...
Competent predicate abstraction in model checking被引量：4
《Science China(Information Sciences)》2011年第2期258-267,共10页LI Li SONG XiaoYu GU Ming LUO XiangYu 
supported by the National Basic Research Program of China (Grant No. 2004CB719406);the National Natural Science Foundation of China (Grant Nos. 60635020, 90718039, 60763004)
The paper presents a new approach to computing the abstract state and a maximum weight heuristic method for finding the shortest counter-example in verification of imperative programs. The strategy is incorporated in ...
关键词：PROGRAM model checking predicate abstraction weight heuristic 
Histogram-Based Estimation of Distribution Algorithm:A Competent Method for Continuous Optimization被引量：6
《Journal of Computer Science & Technology》2008年第1期35-43,共9页丁楠 周树德 孙增圻 
This work is funded by the National Grand Fundamental Research 973 Program of China(Grant No.G2002cb312205).
Designing efficient estimation of distribution algorithms for optimizing complex continuous problems is still a challenging task. This paper utilizes histogram probabilistic model to describe the distribution of popul...
关键词：evolutionary algorithm estimation of distribution algorithm histogram probabilistic model surrounding effect shrinking strategy 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部