PHENYTOIN

作品数：25被引量：20H指数：2
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相关领域：医药卫生更多>>
相关作者：竟永华李行郭剑非吴体成杨健全更多>>
相关机构：辛辛那提大学川北医学院巴中市人民医院更多>>
相关期刊：《中国处方药》《中华物理医学与康复杂志》《World Journal of Methodology》《Journal of Traditional Chinese Medicine》更多>>
相关基金：国家自然科学基金更多>>
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Pregnenolone 16α-carbonitrile negatively regulates hippocampal cytochrome P450 enzymes and ameliorates phenytoin-induced hippocampal neurotoxicity
《Journal of Pharmaceutical Analysis》2023年第12期1510-1525,共16页Shuai Zhang Tingting Wang Ye Feng Fei Li Aijuan Qu Xiuchen Guan Hui Wang Dan Xu 
supported in part by grants from the National Natural Science Foundation of China(Grant Nos.:81973405,82122071,and 82030111)to Dan Xu;Hui Wang,the National Key R&D Program of China(Grant No.:2020YFA0803900)to Hui Wang;the Hubei Provincial Natural Science Foundation Outstanding Youth Found,China(Grant No.:2022CFA083).
The central nervous system is susceptible to the modulation of various neurophysiological processes by the cytochrome P450 enzyme(CYP),which plays a crucial role in the metabolism of neurosteroids.The antiepileptic dr...
关键词：Pregnenolone 16a-carbonitrile Pregnane X receptor Hippocampus Glucocorticoid receptor Phenytoin sodium NEUROTOXICITY 
ANTAGONISM OF TOTAL FLAVONES OF GYNOSTEMMA PENTAPHYLLUM (THUNB) MAK TO ANIMAL EXPERIMENTAL ARRHYTHMIA被引量：2
《Journal of Pharmaceutical Analysis》1999年第2期125-128,共4页Li Le,Zhuang Feier,Zhao Gengsheng Department of Pharmacology, Xi′an Medical University, Xi′an 710061 
The action of total flavones of Gynostemma pentaphyllum (Thunb) Mak (TFG) 60 mg/kg i.v. could prevent arrhythmias induced by drugs and myocardial ischemia were investigated. In anesthetized rats and guinea pigs. The r...
关键词：total flavones of Gynostemma pentaphyllum (Thunb) Mak PHENYTOIN ACONITINE barium chloride calcium choride ARRHYTHMIA ischemia myocarial 
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