ENTEROENDOCRINE

作品数:5被引量:12H指数:2
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相关领域:医药卫生生物学更多>>
相关期刊:《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》《Food and Health》《World Journal of Stem Cells》更多>>
相关基金:北京市自然科学基金国家自然科学基金更多>>
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Duodenal mucosal ablation with irreversible electroporation reduces liver lipids in rats with non-alcoholic fatty liver disease
《World Journal of Gastroenterology》2025年第16期89-100,共12页Jia-Wei Yu Qi Zhao Pei-Xi Li Ya-Xuan Zhang Bi-Xuan Gao Lin-Biao Xiang Xiao-Yu Liu Lei Wang Yi-Jie Sun Ze-Zhou Yang Yu-Jia Shi Yun-Fei Chen Meng-Bo Yu Hong-Ke Zhang Lei Zhang Qin-Hong Xu Lu Ren Dan Li Yi Lyu Feng-Gang Ren Qiang Lu 
Supported by the National Key Research and Development Program,No.2023YFF0713700 and No.2023YFF0713705;Common Technology R&D Platform of Shaanxi Province,No.2023GXJS-01-1-2;the Cyrus Tang Foundation Chung Ying Young Scholars Program.
BACKGROUND Duodenal mucosal ablation(DMA)using irreversible electroporation(IRE)with a glucagon-like peptide-1 receptor agonist has been clinically shown to reduce liver lipid deposition in non-alcoholic fatty liver d...
关键词:Duodenal mucosal ablation Irreversible electroporation Non-alcoholic fatty liver disease ENTEROENDOCRINE Duodenal permeability 
Sodium oligomannate activates the enteroendocrine-vagal afferent pathways in APP/PS1 mice
《Acta Pharmacologica Sinica》2024年第9期1821-1831,共11页Hua-shan Gong Jing-pei Pan Fei Guo Mei-mei Wu Li Dong Yang Li Wei-fang Rong 
National Natural Science Foundation of China(32171118,82370565,31671049,31371066);National Key New Drug Creation Program of China(2018ZX09711002-002-012);Shanghai Municipal Science and Technology Major Project(184319071000 and 19140903102);Innovative Research Team of High-level Local Universities in Shanghai(SHSMU-ZDCX20211102).
Enteroendocrine cells(EECs)and vagal afferent neurons constitute functional sensory units of the gut,which have been implicated in bottom-up modulation of brain functions.Sodium oligomannate(GV-971)has been shown to i...
关键词:sodium oligomannate gut-brain axis enteroendocrine cells vagus nerve sweet taste receptor TRPA1 channel 
Dietary Modulation of Glucagon-like Peptide 1 Secretion:insights and innovations
《Food and Health》2024年第2期42-48,共7页Qing-Yu Wang Jian-Ping Cai 
This work was supported in part by grants from National Key Research&Development Program of China(No.2022YFC3602102);Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(No.2021-1-I2M-050);National Natural Science Foundation of China(No.82170856);China Postdoctoral Science Foundation(No.2022M710456).
Glucagon-like peptide-1(GLP-1),a signal peptide hormone produced by enteroendocrine L cells from the distal small intestine and colon,is a crucial regulator of glycemic control,gastric emptying,satiety,and body weight...
关键词:GLP-1 INTESTINE enteroendocrine L-cells NUTRIENT bacteria-derived product 
Pancreatic β cell regeneration induced by clinical and preclinical agents被引量:8
《World Journal of Stem Cells》2021年第1期64-77,共14页Kang-Li Wang Ming Tao Tian-Jiao Wei Rui Wei 
Supported by the National Key Research and Development Program of China,No.2016YFA0100501;the National Natural Science Foundation of China,No.81770768 and No.81970671;and the Natural Science Foundation of Beijing,No.7192225.
Diabetes,one of the most common chronic diseases in the modern world,has pancreaticβcell deficiency as a major part of its pathophysiological mechanism.Pancreatic regeneration is a potential therapeutic strategy for ...
关键词:βcell regeneration βcell dedifferentiation Cell proliferation Pancreatic progenitors α-to-βcell transdifferentiation Enteroendocrine progenitor cells 
Possible role of intestinal stem cells in the pathophysiology of irritable bowel syndrome被引量:4
《World Journal of Gastroenterology》2020年第13期1427-1438,共12页Magdy El-Salhy 
The pathophysiology of irritable bowel syndrome(IBS)is not completely understood.However,several factors are known to play a role in pathophysiology of IBS such as genetics,diet,gut microbiota,gut endocrine cells,stre...
关键词:DIET GUT ENTEROENDOCRINE cells GUT MICROBIOTA Low grade inflammation Stress 
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