Supported by National Sci-tech Support Plant during Twelfth Five-Year Plan(2015BAD1101);Earmarked Fund for China Agriculture Research System(CAR-38)~~
Macrolide antibiotics have been widely used in clinic due to their good antibacterial effects and high safety, but the drug-resistant bacteria appear constantly. To solve the problem of drug resistance in pathogens, s...
msrA encodes an efflux protein in Staphylococcus spp.that confers inducible resistance to macrolides,such as erythromycin(ERY),but not telithromycin(TEL).Thus,msrA+S.aureus remain susceptible to TEL.Production of msrA...
Background The emergence of bacterial resistance to commonly used antibiotics, such as macrolides, is complicating the management of respiratory tract infections (RTIs). Telithromycin, a ketolide antimicrobial struc...