supported by the National Key Research and Development Program(2022YFB3805800);National Natural Science Foundation of China(52473307,22208178,62301290);Taishan Scholar Program of Shandong Province in China(tsqn202211116);Shandong Provincial Universities Youth Innovation Technology Plan Team(2023KJ223);Natural Science Foundation of Shandong Province of China(ZR2023YQ037,ZR2020QE074,ZR2023QE043,ZR2022QE174);Shandong Province Science and Technology Small and Medium sized Enterprise Innovation Ability Enhancement Project(2023TSGC0344,2023TSGC1006);Natural Science Foundation of Qingdao(23-2-1-249-zyyd-jch,24-4-4-zrjj-56-jch);Anhui Province Postdoctoral Researcher Research Activity Funding Project(2023B706);Qingdao Key Technology Research and Industrialization Demonstration Projects(23-1-7-zdfn-2-hz);Qingdao Shinan District Science and Technology Plan Project(2022-3-005-DZ);Suqian Key Research and Development Plan(H202310);Jinan City-School Integration Development Strategy Project for the Year 2023 under Grant(JNSX2023088).
Rehabilitation training is believed to be an effectual strategy that canreduce the risk of dysfunction caused by spasticity.However,achieving visualizationrehabilitation training for patients remains clinically challe...
supported by the United States Department of Veterans Affairs Rehabilitation Research and Development Service (RR&D)[Merit Review Award numbers B3123-I/101 RX003123 and B3986-R/I01 RX003986-01A1]。
Traumatic brain inju ry-induced unfavorable outcomes in human patients have independently been associated with dysregulated levels of monoamines,especially epinephrine,although few preclinical studies have examined th...
the National Key R&D Program of China(Grant No.2019YFC1709900);National Natural Science Foundation of China(Grant No.71804022);Natural Science Foundation of Henan province(Grant No.232300420256);Medical technologies R&D Program of Henan province(Grant No.LHGJ20220348).
Background:To investigate the effects of acupuncture on post-stroke limb spasm model rats and the underlying mechanism.Methods:A total of 50 Sprague-Dawley rats were randomly divided into three groups,Control group(10...
supported by the Science and Technology Fund of Chengdu Medical College(CYZ18-29);the Sichuan Science and Technology Program(2022JDRC0127).
Cerebral palsy is a common chronic disabling disease in children with special needs,and rehabilitation for cerebral palsy is characterized by a long period,multiple methods and limited efficacy.Due to the limited moto...
Objective:To analyze the impact of comprehensive rehabilitation therapy of traditional Chinese medicine(TCM)(based on modern rehabilitation training)on the spasticity and motor function in stroke patients with hemiple...
Supported by National Natural Science Foundation of China:81673886;Key R&D plan of the autonomous Region:2021BEB04023;School level project of Ningxia Medical University:XT2020025。
Stroke may cause upper motor neurons lesions, and thus limb spasm may occur. Brain plasticity refers to the brain's ability to change and adapt the environment and experience when the nervous system is damaged. Acupun...
Supported by Youth Project of National Natural Science Foundation of China(81501080);Funding Project for Introducing Overseas Students in Hebei Provincial Department of Human Resources and Social Security(C20190174);Construction of Chengde Biomedical Industry Research Institute(202205B086)。
[Objectives]To investigate the spasticity of rat tail and the expression of dopamine receptor-1(DRD1)mRNA in the spinal cord after spinal cord injury(SCI)induced tail spasticity in rats.[Methods]Adult male Wistar rats...
Supported by the China Postdoctoral Science Foundation:Research on the Mechanism of Baishaoluoshi Decoction in Improving Poststroke Spasticity by KCC2-GABAAR Based on the Theory of“Gan Zhu Jin”(No.2020M682571);Natural Science Foundation of Hunan Province China:Research on the Mechanism of Post-stroke Spasticity by KCC2--GABAAR-Motoneuron Excitability and Chinese Traditional Medicine Intervention Based on the Theory of“Gan Zhu Jin”(No.2019JJ50343);the Scientific Research Project of Education Department of Hunan Province:Research on the Mechanism of Axonal Regeneration and TCM Intervention in Post-Stroke Spasticity Based on the Theory of“Gan Zhu Jin”by Slit-Robo Pathway(No.19C1423)。
OBJECTIVE:To evaluate the efficacy of Baishao Luoshi decoction(白芍络石方,BD)on synaptic plasticity in rats with post stroke spasticity(PSS),and to study the mechanism behind the action.METHODS:The PSS model of rat wa...
supported by the National Natural Science Foundation of China,Nos.82071400,81870979;the Scientific Research Foundation of China Rehabilitation Research Center,No.2020cz-01;the Special Capital Health Research and Development of China,No.2018-1-6011(all to JJL)。
Spinal cord injury is a severe and devastating disease,and spasticity is a common and severe complication that is notoriously refractory to treatment.However,the pathophysiological mechanisms underlying spasticity and...
Supported by BTL Industries Ltd.Prague,Czech Republic。
BACKGROUND Approximately 65%-78%of patients with a spinal cord injury(SCI)develop any symptom of spasticity.The aim of this study was to investigate the tolerability and short-term effects of radial extracorporeal sho...