BACKGROUND Congenital heart disease is most commonly seen in neonates and it is a major cause of pediatric illness and childhood morbidity and mortality.AIM To identify and build the best predictive model for predicti...
BACKGROUND The association between congenital heart disease and chronic kidney disease is well known.Various mechanisms of kidney damage associated with congenital heart disease have been established.The etiology of k...
the National Science Fund for Distinguished Young Scholars(81525002,2016-2020).
Objective Many physiological and pathological conditions,including cyanotic congenital heart diseases(CCHD),are accompanied by chronic hypoxia,which might interfere with the transcription process.However,the transcrip...
Background Cyanotic congenital heart disease(CCHD)is one ofthe most common birth anomaly,in which chronic hypoxia is the basic pathophysiological process.Researches in the protective mechanisms of cardiomyocytes to ch...
Background:The levels of ghrelin and tumor necrosis factor alpha (TNF-a) are considered biological markers of congenital heart diseases (CHD).The present meta-analysis was conducted to investigate the clinical signifi...
AIM:To evaluate the impact of long term permanent hypoxemia noticed in patients with non operated congenital cyanogenic cyanotic cardiopathy on liver stiffness.METHODS:We included ten adult patients with non operated ...
This study was supported by grants from the National Natural Science Foundation of China (No. 81100116), the Beijing Natural Science Foundation (No. 7112046), and Capital Citizens' Health Project Cultivation of Beijing Municipal Science and Technology Commissions (No. Z 111100074911001).Acknowledgments: The authors are grateful to Dr. LI Gang and Dr. XU Yu-lin for the animal experiment's assistance, and ZHANG Yanbin and ZHANG Shao-bin for their bioinformatics assistance.
Background Cyanotic congenital heart defects with decreased pulmonary blood flow due to lung ischemia,hypoxia,and others lead to infant morbidity and mortality more than acyanotic heart disease does.Despite the great ...