CORONAVIRUSES

作品数：52被引量：111H指数：6
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Individual virome analysis reveals the general co-infection of mammal-associated viruses with SARS-related coronaviruses in bats
《Virologica Sinica》2024年第4期565-573,共9页Hao-Rui Si Ke Wu Jia Su Tian-Yi Dong Yan Zhu Bei Li Ying Chen Yang Li Zheng-Li Shi Peng Zhou 
supported by the National Key R&D Program of China(2021YFC2300901 to P.Z.);China Natural Science Foundation for outstanding scholars(82325032 to P.Z.);the Self-Supporting Program of Guangzhou Laboratory(SRPG22-001 to P.Z.;GZNL2023A01001 to ZLS).
Bats are the natural reservoir hosts for SARS-related coronavirus(SARSr-CoV)and other highly pathogenic microorganisms.Therefore,it is conceivable that an individual bat may harbor multiple microbes.However,there is l...
关键词：Bat Microbiome SARS-related coronavirus CO-INFECTION Alphacoronavirus 
Pangolin HKU4-related coronaviruses found in greater bamboo bats from southern China
《Virologica Sinica》2023年第6期868-876,共9页Min Guo Kai Zhao Xingwen Peng Xiangyang He Jin Deng Bo Wang Xinglou Yang Libiao Zhang 
the Special Foundation for the National Science and Technology Basic Research Program of China(2021FY100303);the Guangdong Provincial Science and Technology Program(2021B1212050021,2021B1212110003);the GDAS Special Project of Science and Technology Development(2021GDASYL-20210103052);the Young Top-notch Talent Cultivation Program of Hubei Province and the Youth Innovation Promotion Association of the Chinese Academy of Sciences(CAS)(2019328).
Coronavirus(CoV)spillover originating from game animals,particularly pangolins,is currently a significant concern.Meanwhile,vigilance is urgently needed for coronaviruses carried by bats,which are known as natural res...
关键词：CORONAVIRUS Pangolin HKU4r-CoV Bat HKU4r-CoV Tylonycteris robustula Spillover risk 
Identification of a receptor tyrosine kinase inhibitor CP-724714 inhibits SADS-CoV related swine diarrhea coronaviruses infection in vitro
《Virologica Sinica》2023年第5期778-786,共9页Ling Zhou Cheng Li Ruiyu Zhang Qianniu Li Yuan Sun Yaoyu Feng Tian Lan Jingyun Ma 
This work was funded by the Guangdong Major Project of Basic and Applied Basic Research(No.2020B0301030007);the Natural Science Foundation of Guangdong Province(2022A1515012473,2020A1515010220);the Science and Technology Program of Guangzhou City of China(2023B03J1310.)。
The outbreak of the COVID-19 epidemic in 2020 has caused unprecedented panic among all mankind,pointing the major importance of effective treatment.Since the emergence of the swine acute diarrhea syndrome coronavirus(...
关键词：SADS-CoV CORONAVIRUS Antiviral agents HER2 CP-724714 
Porcine Coronaviruses: Overview of the State of the Art被引量：23
《Virologica Sinica》2021年第5期833-851,共19页Hanna Turlewicz-Podbielska Małgorzata Pomorska-Mo´l 
supported by the National Science Centre,Poland,under research project(DEC-2014/13/B/NZ6/02566);statutory funding 506.514.05.00 of the Department of Preclinical Sciences and Infectious Diseases,Faculty of Veterinary Medicine and Animal Science,Poznan University of Life Sciences,Poznan,Poland。
Like RNA viruses in general,coronaviruses(CoV)exhibit high mutation rates which,in combination with their strong tendency to recombine,enable them to overcome the host species barrier and adapt to new hosts.It is curr...
关键词：CORONAVIRUS PIG EMERGING Re-emerging 
A Comprehensive Review of Animal Models for Coronaviruses: SARSCoV-2, SARS-CoV, and MERS-CoV被引量：7
《Virologica Sinica》2020年第3期290-304,共15页Ashutosh Singh Rahul Soloman Singh Phulen Sarma Gitika Batra Rupa Joshi Hardeep Kaur Amit Raj Sharma Ajay Prakash Bikash Medhi 
The recent outbreak of coronavirus disease(COVID-19) caused by the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) has already affected a large population of the world. SARS-CoV-2 belongs to the same...
关键词：CORONAVIRUSES SARS MERS COVID-19 Animal model 
Recent progress in the discovery of inhibitors targeting coronavirus proteases被引量：4
《Virologica Sinica》2016年第1期24-30,共7页Haofeng Wang Song Xue Haitao Yang Cheng Chen 
supported by the Tianjin University Undergraduate Research Foundation;Tianjin University-Hainan University Collaborative Foundation;National Natural Science Foundation of China (No.31300150);Tianjin Marine Science and Technology Program (No.KJXH2014-16)
Coronaviruses(CoVs) can cause highly prevalent diseases in humans and animals. The fatal outbreak of severe acute respiratory syndrome(SARS) and Middle East respiratory syndrome(MERS) highlights the threat posed by th...
关键词：coronaviruses main protease protease inhibitors 
Coexistence of multiple coronaviruses in several bat colonies in an abandoned mineshaft被引量：5
《Virologica Sinica》2016年第1期31-40,共10页Xing-Yi Ge Ning Wang Wei Zhang Ben Hu Bei Li Yun-Zhi Zhang Ji-Hua Zhou Chu-Ming Luo Xing-Lou Yang Li-Jun Wu Bo Wang Yun Zhang Zong-Xiao Li Zheng-Li Shi 
funded by the National Natural Science Foundation of China(81290341);Scientific and Technological Basis Special Project(2013FY113500);China Mega-Project for Infectious Disease(2014ZX 10004001-003)from the Minister of Science and Technology of the People’s Republic of China;USNIAID(R01AI110964)
Since the 2002–2003 severe acute respiratory syndrome(SARS) outbreak prompted a search for the natural reservoir of the SARS coronavirus, numerous alpha- and betacoronaviruses have been discovered in bats around the ...
关键词：coronavirus bat coinfection mineshaft 
Comparison of lentiviruses pseudotyped with S proteins from coronaviruses and cell tropisms of porcine coronaviruses被引量：2
《Virologica Sinica》2016年第1期49-56,共8页Jingjing Wang Feng Deng Gang Ye Wanyu Dong Anjun Zheng Qigai He Guiqing Peng 
supported by the National Natural Science Foundation of China (Grant No.31372440)
The surface glycoproteins of coronaviruses play an important role in receptor binding and cell entry. Different coronaviruses interact with their specific receptors to enter host cells. Lentiviruses pseudotyped with t...
关键词：Coronavirus spike proteins receptor binding cell entry pseudotyped virus 
Longitudinal surveillance of SARS-like coronaviruses in bats by quantitative real-time PCR被引量：3
《Virologica Sinica》2016年第1期78-80,共3页Mei-Niang Wang Wei Zhang Yu-Tao Gao Ben Hu Xing-Yi Ge Xing-Lou Yang Yun-Zhi Zhang Zheng-Li Shi 
funded by the National Natural Science Foundation of China (81290341);China Mega-Project for Infectious Disease (2014ZX10004001-003) from the Minister of Science and Technology of the People’s Republic of China;USNIAID (R01AI110964)
Dear Editor,The 2002–2003 severe acute respiratory syndrome coronavirus（SARS-CoV）（Drosten et al.,2003）caused human pandemics that began in China and spread globally.Subsequently,
关键词：surveillance diverse coronavirus globally transcribed spread transcripts exponential cloned promoter 
Indirect Enzyme-Linked Immunosorbent Assay Based on the Nucleocapsid Protein of SARS-like Coronaviruses被引量：1
《Virologica Sinica》2009年第2期146-151,共6页Jun-fa YUAN Yan LI Hua-jun ZHANG Peng ZHOU Zhen-hua KE Yun-zhi ZHANG Zheng-li SHI 
The State Key Program for Basic Research Grant (2005CB523004) ;The Knowledge InnovationProgram Key Project (KSCX1-YW-R-07).
The nucleocapsid protein(N) is a major structural protein of coronaviruses. The N protein of bat SARS-like coronavirus(SL-CoV) has a high similarity with that of SARS-CoV. In this study,the SL-CoV N protein was expres...
关键词：SARS-like CoV Nucleocapsid protein Indirect ELISA 
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