This work was funded by the Guangdong Major Project of Basic and Applied Basic Research(No.2020B0301030007);the Natural Science Foundation of Guangdong Province(2022A1515012473,2020A1515010220);the Science and Technology Program of Guangzhou City of China(2023B03J1310.)。
The outbreak of the COVID-19 epidemic in 2020 has caused unprecedented panic among all mankind,pointing the major importance of effective treatment.Since the emergence of the swine acute diarrhea syndrome coronavirus(...
Objective:To compare the effects of coronaviruses,such as Middle East respiratory syndrome coronavirus(MERS-CoV)or coronavirus disease 2019(COVID-19)caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2...
Severe acute respiratory syndrome coronavirus(SARS-CoV),Middle East respiratory syndrome coronavirus(MERS-CoV),and SARS-CoV-2 are three kinds of coronaviruses that are exceptionally pathogenic to humans via zoonotic i...
The State Key Program for Basic Research Grant (2005CB523004) ;The Knowledge InnovationProgram Key Project (KSCX1-YW-R-07).
The nucleocapsid protein(N) is a major structural protein of coronaviruses. The N protein of bat SARS-like coronavirus(SL-CoV) has a high similarity with that of SARS-CoV. In this study,the SL-CoV N protein was expres...