SARS-COV

作品数：3416被引量：7943H指数：38
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相关机构：中国科学院中国医学科学院北京协和医学院军事医学科学院武汉大学更多>>
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Landscape of chimeric RNAs in COVID-19 patient blood
《Genes & Diseases》2025年第3期599-610,共12页Samuel Haddox Ping Wu Sandeep Singh Fujun Qin Jack Engel Andrea Kian Syed Ahmad Hui Li Peng Wu 
supported by the National Institutes of Health(USA)(No.R01GM132138 to H.L.).
Despite the availability of efficacious vaccines, COVID-19 persists and our knowledge of how SARS-CoV-2 infection affects host transcriptomics remains incomplete. Transcriptome analysis, which has progressed our under...
关键词：BLOOD Chimeric RNA COVID-19 PTBP1 SARS-CoV-2 
MicroRNA-155 modulation by renin-angiotensin system inhibitors may underlie their enigmatic role in COVID-19
《World Journal of Experimental Medicine》2025年第2期246-252,共7页Konstantinos I Papadopoulos Alexandra Papadopoulou Tar Choon Aw 
Severe acute respiratory coronavirus-2(SARS-CoV-2)infection course differs between the young and healthy and the elderly with co-morbidities.In the latter a potentially lethal coronavirus disease 2019(COVID-19)cytokin...
关键词：Angiotensin converting enzyme inhibitors Angiotensin II type 1 receptor blocker COVID-19 MicroRNA Mineralocorticosteroid receptor antagonists MicroRNA-155 Renin-angiotensin system inhibitors SARS-CoV-2 Sodium-glucose transporter 2 
Effect and Safety of Fuzheng Huazhuo Decoction against Prolonged SARS-CoV-2 Clearance:A Retrospective Cohort Study
《Chinese Journal of Integrative Medicine》2025年第5期387-393,共7页ZHANG Wen WU Hong-ze XU Xiang-ru PU Yu-ting CHEN Cai-yu DENG Rou CAO Min SUN Ding YI Hui ZHOU Shuang FANG Bang-jiang 
Supported by the State Administration of Traditional Chinese Medicine;Traditional Chinese Medicine for the Prevention and Treatment of Novel Coronavirus Pneumonia Emergency and Special Project (No. 2022ZYLCYJ05-4);Shanghai University of Traditional Chinese Medicine,Traditional Chinese Medicine on Prevention and Treatment of Novel Coronavirus Pneumonia Emergency and Special Project (Nos. 2022YJ-03 and 2022YJ-06)。
Objective To evaluate the effect and safety of Chinese medicine(CM)Fuzheng Huazhuo Decoction(FHD)in treating patients with coronavirus disease 2019(COVID-19)who persistently tested positive for severe acute respirator...
关键词：Chinese medicine Fuzheng Huazhuo Decoction coronavirus disease 2019 prolonged viral clearance 
Comparison of the pathogenicity and neutrophil and monocyte response between SARS-CoV-2 prototype and Omicron BA.1 in a lethal mouse model
《Animal Models and Experimental Medicine》2025年第4期707-717,共11页Na Rong Jing Wu Binbin Zhao Wanjun Peng Hekai Yang Gengxin Zhang Dangting Ruan Xiaohui Wei Jiangning Liu 
supported by Beijing Natural Science Foundation(Grant No.Z210014);National Natural Science Foundation of China(Grant No.32070543);National Key Research and Development Project of China(Grant No.2022YFC2303404);CAMS Innovation Fund for Medical Sciences(CIFMS)(Grant No.2022-12M-CoV19-002)
Background:SARS-CoV-2,first identified in late 2019,has given rise to numerous variants of concern(VOCs),posing a significant threat to human health.The emer-gence of Omicron BA.1.1 towards the end of 2021 led to a pa...
关键词：animal model SARS-CoV-2 Omicron BA.1 MONOCYTE NEUTROPHIL 
COVID-19 Vaccine Distribution Patterns for Prioritized Age Group: Analysis of European Nations
《Open Journal of Epidemiology》2025年第1期1-18,共18页Ogbonnaya Ezichi Victor Okpanachi Joy Jibunoh Wuraola Awosan Prosper Tchoumo Anthony Akande Chibuzor Amaechi Jubril Sanusi Funmilayo Ogunsanwo Rofiat Adesina 
The emergence of the SARS-CoV-2 virus resulted in a health and economic crisis worldwide. Although everyone is susceptible to COVID-19, the elderly have compromised immune systems and often suffer from chronic underly...
关键词：SARS-CoV-2 COVID-19 Vaccines Prioritized Age Group European Nations 
神经炎症:以少突胶质细胞为中心的视角
《神经损伤与功能重建》2025年第3期F0003-F0003,共1页Lindsay K Festa Kelly L Jordan-Sciutto Judith B Grinspan 王晶(编译) 
慢性神经炎症由中枢神经系统(CNS)内的星形胶质细胞和小胶质细胞驱动,并伴随外周免疫系统的浸润,是多种神经系统疾病的重要病理机制。数十年来,研究几乎完全聚焦于神经炎症如何影响神经元功能;然而,越来越多的证据表明,少突胶质细胞谱...
关键词：SARS-CoV2 人类免疫缺陷病毒 多发性硬化 少突胶质细胞 围产期脑白质损伤 创伤性脑损伤 
孕期感染SARS-CoV-2与接种COVID-19疫苗对子代早期发育的影响:一项苏格兰基于人群的回顾性队列研究
《中华围产医学杂志》2025年第3期210-210,共1页张馨月 
孕产妇是新型冠状病毒(SARS-CoV-2)重症感染的高风险人群。但孕期SARS-CoV-2暴露对子代发育的潜在影响尚不明晰。而关于孕期接种COVID-19疫苗,尽管没有证据表明其对子代发育是不安全的,但还需对儿童远期发育结局进行随访研究。明确孕期...
关键词：子代早期发育 孕期感染SARS-CoV-2 
Rabies virus-based oral and inactivated vaccines protect minks against SARS-CoV-2 infection and transmission
《Journal of Integrative Agriculture》2025年第3期1198-1211,共14页Hong Huo Shuang Xiao Jinming Wang Xijun Wang Jinying Ge Gongxun Zhong Zhiyuan Wen Chong Wang Jinliang Wang Han Wang Xijun He Lei Shuai Zhigao Bu 
supported by the National Key Research and Development Program of China(2021YFC2301700);the Natural Science Foundation of Heilongjiang Province,China(YQ2022C040)。
Minks are highly susceptible to SARS-CoV-2,and have transmitted SARS-CoV-2 to humans.Oral immunization is one of the most promising strategies to prevent SARS-CoV-2 infection and transmission in minks.Here,we generate...
关键词：SARS-CoV-2 rabies virus oral vaccine inactivated vaccine MINK 
SARS-CoV-2 proteins show great binding affinity to resin composite monomers and polymerized chains
《World Journal of Experimental Medicine》2025年第1期96-103,共8页Pedro Henrique Sette-de-Souza Moan Jéfter Fernandes Costa Boniek Castillo Dutra Borges 
BACKGROUND Due to saliva and salivary glands are reservoir to severe acute respiratory syndrome-coronavirus 2(SARS-CoV-2),aerosols and saliva droplets are primary sources of cross-infection and are responsible for the...
关键词：Composite resins COVID-19 SARS-CoV-2 Dental restorations Molecular docking simulation DENTISTRY 
Enabling the immune escaped etesevimab fully-armed against SARS-CoV-2 Omicron subvariants including KP.2
《hLife》2025年第3期132-145,共14页Chao Su Juanhua He Yufeng Xie Yu Hu Xin Li Shitong Qiao Peipei Liu Min Huang Rong Zhang Liang Wang Zhen Chang Wenqiao Sun Ke Xu Jing Zhang Longxing Cao Pengcheng Han Xin Zhao Jianxun Qi Qihui Wang Mengsu Yang George Fu Gao 
supported by the National Natural Science Foundation of China(82225021);the National Key R&D Program of China(2022YFC2303403,2021YFA1300803,2021YFA1301404).
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is continuously evolving since 2019.Some monoclonal antibodies(mAbs)have been developed and widely used,such as etesevimab(CB6)developed by Eli-Lilly/Junshi.H...
关键词：etesevimab(CB6) severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) receptor-binding domain(RBD) broad-spectrum and affinity-mature antibody design(BAADesign) antibody 
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