PRO-INFLAMMATORY

作品数：84被引量：278H指数：9
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Xuebijing alleviates LPS-induced acute lung injury by downregulating pro-inflammatory cytokine production and inhibiting gasdermin-E-mediated pyroptosis of alveolar epithelial cells被引量：6
《Chinese Journal of Natural Medicines》2023年第8期576-588,共13页ZHANG Cuiping CHEN Xiaoyan WEI Tianchang SONG Juan TANG Xinjun BI Jing CHEN Cuicui ZHOU Jian SU Xiao SONG Yuanlin 
supported by the National Natural Science Foundation of China(Nos.82130001,82200089,8173000,81800077,and 82070045);Shanghai Sailing Program(No.22YF1406100);the National Key R&D Plan(No.2020YFC2003700);the Science and Technology Commission of Shanghai Municipality(Nos.20Z11901000,20DZ2261200,and 20XD1401200);Shanghai Municipal Science and Technology Major Project,Clinical Research Plan of SHDC(No.SHDC2020CR5010-002);Shanghai Municipal Key Clinical Specialty(No.shslczdzk02201).
Acute lung injury/acute respiratory distress syndrome(ALI/ARDS)is characterized by diffuse alveolar injury primarily caused by an excessive inflammatory response.Regrettably,the lack of effective pharmacotherapy curre...
关键词：PYROPTOSIS Gasdermin-E TNF-α XUEBIJING Acute lung injury 
In vivo and in vitro anti-sepsis effects of physcion 8-O-β- glu- copyranoside extracted from Rumexjaponicus被引量：2
《Chinese Journal of Natural Medicines》2017年第7期534-539,共6页FU Wei-Jun TANG Jian-Jun WANG Hui WEI Hong-Yun CAI Shu-Min ZENG Zhen-Hua CHEN Hui CHEN Zhong-Qing 
The present study was designed to investigate the anti-sepsis effects of physcion 8-O-β-glucopyranoside (POG) isolated from Rumex japonicas and explore its possible pharmacological mechanisms. POG was extracted from ...
关键词：Anti-sepsis TLR-4 TLR-2 PRO-INFLAMMATORY cytokines LPS 
A polysaccharide purified from Radix Adenophorae promotes cell activation and pro-inflammatory cytokine production in murine RAW264.7 macrophages被引量：7
《Chinese Journal of Natural Medicines》2016年第5期370-376,共7页LI Jing-Wen LIU Yang LI Bao-Hui WANG Yue-Yang WANG Hui ZHOU Chang-Lin 
supported by the National Science and Technology Major Project Foundation of China(No.2012ZX09102301-003);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)
Radix Adenophorae, a traditional Chinese medicine, has been reported to have a variety of biological functions. In the present study, a polysaccharide component, Radix Adenophorae Polysaccharide （RAPS）, was purified...
关键词：POLYSACCHARIDE RAPS PURIFICATION Macrophage activation Pro-inflammation 
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