PRO-INFLAMMATORY

作品数：83被引量：276H指数：9
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CORRECTION:Author Correction:Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
《Cell Research》2024年第11期815-815,共1页
Glyphosate as a direct or indirect activator of pro-inflammatory signaling and cognitive impairment
《Neural Regeneration Research》2024年第10期2212-2218,共7页Yukitoshi Izumi Kazuko A.O'Dell Charles F.Zorumski 
supported by MH101874 (to CFZ);MH122379 (to CFZ);the Taylor Family Institute for Innovative Psychiatric Research and the Bantly Foundation (to CFZ)。
Glyphosate-based herbicides are widely used around the world, making it likely that most humans have significant exposure. Because of habitual exposure, there are concerns about toxicity including neurotoxicity that c...
关键词：cognitive impairment GLYPHOSATE microglia NEUROINFLAMMATION ROUNDUP toll-like receptor 4 zinc chelation 
Lentivirus Transduced T Cell Lines Response to Pro-Inflammatory and Antiviral Cytokines in the Presence of HIV
《Journal of Biosciences and Medicines》2024年第10期222-235,共14页Kevin Ventocilla Daniel Miranda Jr. David Jesse Sanchez 
Various studies have attempted to understand HIV infection under a diverse range of stimulants including cytokine stimulation. Pro-inflammatory cytokines, such as TNF-α, have been shown to reactivate HIV latency by i...
关键词：HIV CYTOKINE INTERFERON Cell TNF 
Overlap in oncogenic and pro-inflammatory pathways associated with areca nut and nicotine exposure
《Cancer Pathogenesis and Therapy》2024年第3期187-194,共8页Krati Garg Anuj Kumar Vidisha Kizhakkethil Pramod Kumar Shalini Singh 
supported by intramural funding from the National Institute of Cancer Prevention and Research,Indian Council of Medical Research(No.NICPR/Anuj/intramural/2021/1).
Background:Betel nut/areca nut/Areca catechu is one of the most commonly used psychoactive substance,and is also a major preventable cause of cancer.Unlike other psychoactive substances,such as nicotine,the mechanisms...
关键词：Cancer Areca nut NICOTINE INTERACTOME Cell signaling 
Targeting pro-inflammatory T cells as a novel therapeutic approach to potentially resolve atherosclerosis in humans
《Cell Research》2024年第6期407-427,共21页Lin Fan Junwei Liu Wei Hu Zexin Chen Jie Lan Tongtong Zhang Yang Zhang Xianpeng Wu Zhiwei Zhong Danyang Zhang Jinlong Zhang Rui Qin Hui Chen Yunfeng Zong Jianmin Zhang Bing Chen Jun Jiang Jifang Cheng Jingyi Zhou Zhiwei Gao Zhenjie Liu Ying Chai Junqiang Fan Pin Wu Yinxuan Chen Yuefeng Zhu Kai Wang Ying Yuan Pintong Huang Ying Zhang Huiqin Feng Kaichen Song Xun Zeng Wei Zhu Xinyang Hu Weiwei Yin Wei Chen Jian’an Wang 
supported by the National Key R&D Program of China(2019YFA0110400 to J.A.W.);the National Natural Science Foundation of China(81870292 and 82030014 to J.A.W.,T2394511,92359303,31971237,31470900,and 31522021 to W.C.,82070253 and 82225004 to X.Y.H.,31600751 to W.W.Y.);the Key R&D Projects of Zhejiang Province(2021C03097 to J.A.W.);financial support provided by Binjiang Institute of Zhejiang University(ZY202205SMKY001 for J.A.W.,ZY202205SMKY001 for X.Y.H.);the Ministry of Science and Technology of China(2017ZX10203205 to W.C.);the National Basic Research Program of China(2015CB910800 to W.C.).
Atherosclerosis(AS),a leading cause of cardio-cerebrovascular disease worldwide,is driven by the accumulation of lipid contents and chronic inflammation.Traditional strategies primarily focus on lipid reduction to con...
关键词：IMMUNITY INFLAMMATORY RESOLVE 
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis被引量：2
《Neural Regeneration Research》2024年第3期671-679,共9页Chunyun Liu Shangde Guo Rong Liu Minfang Guo Qing Wang Zhi Chai Baoguo Xiao Cungen Ma 
supported by a grant from the Department of Science and Technology of Shanxi Province,China,No.20210302123477(to CL);Datong Bureau of Science and Technology of China,No.2020152(to CL);the Opening Foundation of Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine,No.2022-KF-03(to CL).
Multiple sclerosis is characterized by demyelination and neuronal loss caused by inflammatory cell activation and infiltration into the central nervous system.Macrophage polarization plays an important role in the pat...
关键词：ANTI-INFLAMMATORY experimental autoimmune encephalomyelitis FASUDIL macrophage multiple sclerosis PRO-INFLAMMATORY Rho kinase 
Nonlinear proinflammatory effect of short-term PM_(2.5)exposure:A potential role of lipopolysaccharide
《Journal of Environmental Sciences》2024年第2期292-300,共9页Fangxia Shen Mutong Niu Haoxuan Chen Ting Zhang Jing Li Haijie Tong Yan Wu 
supported by the National Natural Science Foundation of China (Nos.42075117 and 41807306)。
The association between PM_(2.5)(particulate matter≤2.5μm)short-term exposure and its health effect is non-linear from the epidemiological studies.And this nonlinearity is suggested to be related with the PM_(2.5)he...
关键词：Fine PM PM_(2.5)pro-inflammatory effects Aerosol health effect ENDOTOXIN Oxidative stress 
The role of microglia in depression
《Microenvironment & Microecology Research》2023年第3期10-15,共6页Lester Raymundo Dominguez Huarcaya María Fernanda Dominguez Ríos 
According to studies,neuroinflammation is increasingly being linked to the development of major depressive disorder(MDD).In response to inflammatory stimuli,brain microglia,which are immune cells,can change into react...
关键词：anti-inflammatory pathway major depressive disorder metabolic pathway MICROGLIA microglial pathways as therapeutic targets NEUROINFLAMMATION pro-inflammatory pathway 
Effect of Astragalus-hawthorn on ovarian reproductive function and inflammatory mechanism of action in rats with polycystic ovary syndrome
《Journal of Hainan Medical University》2023年第17期28-33,共6页TIAN Xiu-xiu LI Mei-lin GONG Yu-hang MA Xi-ya ZHANG Xue-juan 
Key R&D Plan Project for Social Development of Shanxi Provincial Department of Science and Technology(No.201903D321224)。
Objective:To investigate the effects of prophylactic administration of Astragalus-Hawthorn on ovarian reproductive function and inflammatory mechanism in rats with polycystic ovary syndrome(PCOS).Methods:Fifty 21-day-...
关键词：Polycystic ovary syndrome Astragalus-Hawthorn Reproductive function Pro-inflammatory factor Anti-inflammatory factor 
Xuebijing alleviates LPS-induced acute lung injury by downregulating pro-inflammatory cytokine production and inhibiting gasdermin-E-mediated pyroptosis of alveolar epithelial cells被引量：6
《Chinese Journal of Natural Medicines》2023年第8期576-588,共13页ZHANG Cuiping CHEN Xiaoyan WEI Tianchang SONG Juan TANG Xinjun BI Jing CHEN Cuicui ZHOU Jian SU Xiao SONG Yuanlin 
supported by the National Natural Science Foundation of China(Nos.82130001,82200089,8173000,81800077,and 82070045);Shanghai Sailing Program(No.22YF1406100);the National Key R&D Plan(No.2020YFC2003700);the Science and Technology Commission of Shanghai Municipality(Nos.20Z11901000,20DZ2261200,and 20XD1401200);Shanghai Municipal Science and Technology Major Project,Clinical Research Plan of SHDC(No.SHDC2020CR5010-002);Shanghai Municipal Key Clinical Specialty(No.shslczdzk02201).
Acute lung injury/acute respiratory distress syndrome(ALI/ARDS)is characterized by diffuse alveolar injury primarily caused by an excessive inflammatory response.Regrettably,the lack of effective pharmacotherapy curre...
关键词：PYROPTOSIS Gasdermin-E TNF-α XUEBIJING Acute lung injury 
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